Efficacy and safety of a crystalline lactulose preparation (SK-1202) in Japanese patients with chronic constipation: a randomized, double-blind, placebo-controlled, dose-finding study
Kasugai, Kunio, Iwai, Hisakazu, Kuboyama, Noboru, Yoshikawa, Aya, Fukudo, Shin
Published in Journal of gastroenterology (01.06.2019)
Published in Journal of gastroenterology (01.06.2019)
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Cross‐over study in hyperammonemia patients for efficacy, safety, and acceptability of a new lactulose preparation (SK‐1202) compared to approved drug
Yoshiji, Hitoshi, Karino, Yoshiyasu, Suzuki, Yoshiyuki, Suzuki, Fumitaka, Uejima, Masakazu, Aikata, Hiroshi, Chayama, Kazuaki, Iwai, Hisakazu, Suzuki, Eiji, Kumada, Hiromitsu
Published in Hepatology research (01.12.2018)
Published in Hepatology research (01.12.2018)
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Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
Ohkura, Takako, Ohta, Kunihiro, Nagao, Takuya, Kusumoto, Kumiko, Koeda, Akiko, Ueda, Tadayoshi, Jomura, Tomoko, Ikeya, Takeshi, Ozeki, Emiko, Wada, Kazuki, Naitoh, Kazushi, Inoue, Yukiko, Takahashi, Naoki, Iwai, Hisakazu, Arakawa, Hiroshi, Ogihara, Takuo
Published in Drug metabolism and pharmacokinetics (2014)
Published in Drug metabolism and pharmacokinetics (2014)
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Utility of human hepatocyte spheroids for evaluation of hepatotoxicity
Ogihara, Takuo, Iwai, Hisakazu, Inoue, Yukiko, Katagi, Jun, Matsumoto, Norihito, Motoi-Ohtsuji, Makiko, Kakiki, Motoharu, Kaneda, Shinya, Nagao, Takuya, Kusumoto, Kumiko, Ozeki, Emiko, Jomura, Tomoko, Tanaka, Sho, Ueda, Tadayoshi, Ohta, Kunihiro, Ohkura, Takako, Arakawa, Hiroshi, Nagai, Daichi
Published in Fundamental Toxicological Sciences (2015)
Published in Fundamental Toxicological Sciences (2015)
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Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
Takako OHKURA, Kunihiro OHTA, Takuya NAGAO, Kumiko KUSUMOTO, Akiko KOEDA, Tadayoshi UEDA, Tomoko JOMURA, Takeshi IKEYA, Emiko OZEKI, Kazuki WADA, Kazushi NAITOH, Yukiko INOUE, Naoki TAKAHASHI, Hisakazu IWAI, Hiroshi ARAKAWA, Takuo OGIHARA
Published in DRUG METABOLISM AND PHARMACOKINETICS (25.10.2014)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (25.10.2014)
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Evaluation report on the cytotoxicity tests to estimate starting doses for acute oral systemic toxicity tests
Yoji Takahashi, Toshihiko Kasahara, Shinobu Wakuri, Teruaki Kodaira, Hisakazu Iwai, Shigenobu Hagino, Shigeo Kono, Yomiko Iwase
Published in Alternatives to Animal Testing and Experimentation (31.10.2019)
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Published in Alternatives to Animal Testing and Experimentation (31.10.2019)
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2-Bromopropane-Induced Hypoplasia of Bone Marrow in Male Rats
Nakajima, Tamie, Shimodaira, Shigetaka, Ichihara, Gaku, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Ichikawa, Ichihito, Kamijima, Michihiro, Yu, Xiaozhong, Xie, Zhelin, Kondo, Hidetaka, Takeuchi, Yasuhiro
Published in Journal of Occupational Health (01.07.1997)
Published in Journal of Occupational Health (01.07.1997)
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Journal Article
Histopathologic Findings of Bone Marrow Induced by 2-Bromopropane in Male Rats
Nakajima, Tamie, Shimodaira, Shigetaka, Ichihara, Gaku, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Ichikawa, Ichihito, Kamijima, Michihiro, Yu, Xiaozhong, Xie, Zhelin, Kondo, Hidetaka, Takeuchi, Yasuhiro
Published in Journal of Occupational Health (01.04.1997)
Published in Journal of Occupational Health (01.04.1997)
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Evaluation report on the cytotoxicity tests to estimate starting doses for acute oral systemic toxicity tests
Yuji Takahashi, Toshihiko Kasahara, Shinobu Wakuri, Terutomo Kohira, Hisakazu Iwai, Shigenobu Hagino, Shigeo Kawano, Yumiko Iwase
Published in Alternatives to Animal Testing and Experimentation (30.09.2014)
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Published in Alternatives to Animal Testing and Experimentation (30.09.2014)
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P-61 Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
ARAKAWA HIROSHI, Takako Ohkura, Kunihiro Ohta, Takuya Nagao, Kumiko Kusumoto, Akiko Koeda, Tadayoshi Ueda, Tomoko Jomura, Takeshi Ikeya, Emiko Ozeki, Yukiko Inoue, Naoki Takahashi, Hisakazu Iwai, Takuo Ogihara
Published in Alternatives to Animal Testing and Experimentation (31.12.2014)
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Published in Alternatives to Animal Testing and Experimentation (31.12.2014)
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1-Bromopropane, an Alternative to Ozone Layer Depleting Solvents, Is Dose-Dependently Neurotoxic to Rats in Long-Term Inhalation Exposure
Ichihara, Gaku, Kitoh, Junzoh, Yu, Xiaozhong, Asaeda, Nobuyuki, Iwai, Hisakazu, Kumazawa, Toshihiko, Shibata, Eiji, Yamada, Tetsuya, Wang, Hailan, Xie, Zhenlin, Takeuchi, Yasuhiro
Published in Toxicological sciences (01.05.2000)
Published in Toxicological sciences (01.05.2000)
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Reproductive Toxicity of 1-Bromopropane, a Newly Introduced Alternative to Ozone Layer Depleting Solvents, in Male Rats
Ichihara, Gaku, Yu, Xiaozhong, Kitoh, Junzoh, Asaeda, Nobuyuki, Kumazawa, Toshihiko, Iwai, Hisakazu, Shibata, Eiji, Yamada, Tetsuya, Wang, Hailan, Xie, Zhenlin, Maeda, Kei-ichiro, Tsukamura, Hiroko, Takeuchi, Yasuhiro
Published in Toxicological sciences (01.04.2000)
Published in Toxicological sciences (01.04.2000)
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Journal Article
EFFECTS OF ATROPINE SULFATE ON RAT HARDERIAN GLANDS
IWAI, Hisakazu, TAGAWA, Yoshiaki, HAYASAKA, Ikuo, YANAI, Tokuma, MASEGI, Toshiaki
Published in Journal of toxicological sciences (30.05.2000)
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Published in Journal of toxicological sciences (30.05.2000)
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NEW INDOLE DERIVATIVE AND DRUG USE THEREOF
KATAOKA DAISUKE, CHIKAMATSU KAORI, MAKINO MICHIHIRO, KITAMOTO KATSUNORI, IWAI HISAKAZU, GOTO IZUMI, HIRAMATSU NAOKI, TORII MASASHI, HIROOKA HIROKO, YAMASHITA ATSUYUKI, TAJIMA YASUMITSU, SUZUKI KIMIE, KONDO YURIE, NAGAI KAZUSHIGE
Year of Publication 29.09.2011
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Year of Publication 29.09.2011
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