Investigation of Metabolomic Changes in Sunitinib-Resistant Human Renal Carcinoma 786-O Cells by Capillary Electrophoresis-Time of Flight Mass Spectrometry
Hatakeyama, Hiroto, Fujiwara, Takuya, Sato, Hiromi, Terui, Ayu, Hisaka, Akihiro
Published in Biological & pharmaceutical bulletin (2018)
Published in Biological & pharmaceutical bulletin (2018)
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Journal Article
A New Intestinal Model for Analysis of Drug Absorption and Interactions Considering Physiological Translocation of Contents
Asano, Satoshi, Yoshitomo, Aoi, Hozuki, Shizuka, Sato, Hiromi, Kazuki, Yasuhiro, Hisaka, Akihiro
Published in Drug metabolism and disposition (01.07.2021)
Published in Drug metabolism and disposition (01.07.2021)
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Journal Article
Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics
Sato, Masanobu, Toshimoto, Kota, Tomaru, Atsuko, Yoshikado, Takashi, Tanaka, Yuta, Hisaka, Akihiro, Lee, Wooin, Sugiyama, Yuichi
Published in Drug metabolism and disposition (01.05.2018)
Published in Drug metabolism and disposition (01.05.2018)
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Journal Article
Effects of ceramide kinase knockout on lipopolysaccharide-treated sepsis-model mice: Changes in serum cytokine/chemokine levels and increased lethality
Tanaka, Ai, Honda, Takuya, Yasue, Masataka, Yamazaki, Risa, Hatakeyama, Hiroto, Hisaka, Akihiro, Mashimo, Masato, Kohama, Takafumi, Nakamura, Hiroyuki, Murayama, Toshihiko
Published in Journal of pharmacological sciences (01.09.2022)
Published in Journal of pharmacological sciences (01.09.2022)
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Journal Article
Trichostatin A modulates cellular metabolism in renal cell carcinoma to enhance sunitinib sensitivity
Sato, Hiromi, Uzu, Miaki, Kashiba, Tatsuro, Fujiwara, Takuya, Hatakeyama, Hiroto, Ueno, Koichi, Hisaka, Akihiro
Published in European journal of pharmacology (15.03.2019)
Published in European journal of pharmacology (15.03.2019)
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Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data
Yamashita, Fumiyoshi, Sasa, Yukako, Yoshida, Shuya, Hisaka, Akihiro, Asai, Yoshiyuki, Kitano, Hiroaki, Hashida, Mitsuru, Suzuki, Hiroshi
Published in PloS one (24.09.2013)
Published in PloS one (24.09.2013)
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Journal Article
Metabolome Shift in Both Metastatic Breast Cancer Cells and Astrocytes Which May Contribute to the Tumor Microenvironment
Sato, Hiromi, Shimizu, Ayaka, Okawa, Toya, Uzu, Miaki, Goto, Momoko, Hisaka, Akihiro
Published in International journal of molecular sciences (11.07.2021)
Published in International journal of molecular sciences (11.07.2021)
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Journal Article
Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors
Cho, Riki, Sakurai, Yu, Jones, Haleigh Sakura, Akita, Hidetaka, Hisaka, Akihiro, Hatakeyama, Hiroto
Published in Cancers (04.12.2020)
Published in Cancers (04.12.2020)
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Assessment of intestinal availability (FG) of substrate drugs of cytochrome p450s by analyzing changes in pharmacokinetic properties caused by drug-drug interactions
Hisaka, Akihiro, Nakamura, Mikiko, Tsukihashi, Ayako, Koh, Saori, Suzuki, Hiroshi
Published in Drug metabolism and disposition (01.10.2014)
Published in Drug metabolism and disposition (01.10.2014)
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Journal Article
Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption
Yoshitomo, Aoi, Asano, Satoshi, Hozuki, Shizuka, Tamemoto, Yuta, Shibata, Yukihiro, Hashimoto, Natsumi, Takahashi, Keita, Sasaki, Yoko, Ozawa, Naoka, Kageyama, Michiharu, Iijima, Takeshi, Kazuki, Yasuhiro, Sato, Hiromi, Hisaka, Akihiro
Published in Drug metabolism and disposition (01.03.2023)
Published in Drug metabolism and disposition (01.03.2023)
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