European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia
Lucas, Jane S, Barbato, Angelo, Collins, Samuel A, Goutaki, Myrofora, Behan, Laura, Caudri, Daan, Dell, Sharon, Eber, Ernst, Escudier, Estelle, Hirst, Robert A, Hogg, Claire, Jorissen, Mark, Latzin, Philipp, Legendre, Marie, Leigh, Margaret W, Midulla, Fabio, Nielsen, Kim G, Omran, Heymut, Papon, Jean-Francois, Pohunek, Petr, Redfern, Beatrice, Rigau, David, Rindlisbacher, Bernhard, Santamaria, Francesca, Shoemark, Amelia, Snijders, Deborah, Tonia, Thomy, Titieni, Andrea, Walker, Woolf T, Werner, Claudius, Bush, Andrew, Kuehni, Claudia E
Published in The European respiratory journal (01.01.2017)
Published in The European respiratory journal (01.01.2017)
Get full text
Journal Article
Axonemal structures reveal mechanoregulatory and disease mechanisms
Walton, Travis, Gui, Miao, Velkova, Simona, Fassad, Mahmoud R., Hirst, Robert A., Haarman, Eric, O’Callaghan, Christopher, Bottier, Mathieu, Burgoyne, Thomas, Mitchison, Hannah M., Brown, Alan
Published in Nature (London) (15.06.2023)
Published in Nature (London) (15.06.2023)
Get full text
Journal Article
International consensus guideline for reporting transmission electron microscopy results in the diagnosis of primary ciliary dyskinesia (BEAT PCD TEM Criteria)
Shoemark, Amelia, Boon, Mieke, Brochhausen, Christoph, Bukowy-Bieryllo, Zuzanna, De Santi, Maria M, Goggin, Patricia, Griffin, Paul, Hegele, Richard G, Hirst, Robert A, Leigh, Margaret W, Lupton, Alison, MacKenney, Karen, Omran, Heymut, Pache, Jean-Claude, Pinto, Andreia, Reinholt, Finn P, Schroeder, Josep, Yiallouros, Panayotis, Escudier, Estelle
Published in The European respiratory journal (01.04.2020)
Published in The European respiratory journal (01.04.2020)
Get full text
Journal Article
Mutations in Outer Dynein Arm Heavy Chain DNAH9 Cause Motile Cilia Defects and Situs Inversus
Fassad, Mahmoud R., Shoemark, Amelia, Legendre, Marie, Hirst, Robert A., Koll, France, le Borgne, Pierrick, Louis, Bruno, Daudvohra, Farheen, Patel, Mitali P., Thomas, Lucie, Dixon, Mellisa, Burgoyne, Thomas, Hayes, Joseph, Nicholson, Andrew G., Cullup, Thomas, Jenkins, Lucy, Carr, Siobhán B., Aurora, Paul, Lemullois, Michel, Aubusson-Fleury, Anne, Papon, Jean-François, O’Callaghan, Christopher, Amselem, Serge, Hogg, Claire, Escudier, Estelle, Tassin, Anne-Marie, Mitchison, Hannah M.
Published in American journal of human genetics (06.12.2018)
Published in American journal of human genetics (06.12.2018)
Get full text
Journal Article
Clinical utility of NGS diagnosis and disease stratification in a multiethnic primary ciliary dyskinesia cohort
Fassad, Mahmoud R., Patel, Mitali P., Shoemark, Amelia, Cullup, Thomas, Hayward, Jane, Dixon, Mellisa, Rogers, Andrew V., Ollosson, Sarah, Jackson, Claire, Goggin, Patricia, Hirst, Robert A., Rutman, Andrew, Thompson, James, Jenkins, Lucy, Aurora, Paul, Moya, Eduardo, Chetcuti, Philip, O'Callaghan, Chris, Morris-Rosendahl, Deborah J, Watson, Christopher M., Wilson, Robert, Carr, Siobhan, Walker, Woolf, Pitno, Andreia, Lopes, Susana, Morsy, Heba, Shoman, Walaa, Pereira, Luisa, Constant, Carolina, Loebinger, Michael R., Chung, Eddie M.K., Kenia, Priti, Rumman, Nisreen, Fasseeh, Nader, Lucas, Jane S., Hogg, Claire, Mitchison, Hannah M.
Published in Journal of medical genetics (01.05.2020)
Published in Journal of medical genetics (01.05.2020)
Get full text
Journal Article
Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma
Thomas, Biju, MD, Rutman, Andrew, CBiol, Hirst, Robert A., PhD, Haldar, Pranab, MD, Wardlaw, Andrew J., PhD, Bankart, John, PhD, Brightling, Christopher E., PhD, O'Callaghan, Christopher, PhD
Published in Journal of allergy and clinical immunology (01.10.2010)
Published in Journal of allergy and clinical immunology (01.10.2010)
Get full text
Journal Article
Culture of primary ciliary dyskinesia epithelial cells at air-liquid interface can alter ciliary phenotype but remains a robust and informative diagnostic aid
Hirst, Robert A, Jackson, Claire L, Coles, Janice L, Williams, Gwyneth, Rutman, Andrew, Goggin, Patricia M, Adam, Elizabeth C, Page, Anthony, Evans, Hazel J, Lackie, Peter M, O'Callaghan, Christopher, Lucas, Jane S
Published in PloS one (25.02.2014)
Published in PloS one (25.02.2014)
Get full text
Journal Article
Respiratory Syncytial Virus Increases the Virulence of Streptococcus pneumoniae by Binding to Penicillin Binding Protein 1a: A New Paradigm in Respiratory Infection
SMITH, Claire M, SANDRINI, Sara, EASTON, Andrew J, ANDREW, Peter W, O'CALLAGHAN, Christopher, DATTA, Sumit, FREESTONE, Primrose, SHAFEEQ, Sulman, RADHAKRISHNAN, Priya, WILLIAMS, Gwyneth, GLENN, Sarah M, KUIPERS, Oscar P, HIRST, Robert A
Published in American journal of respiratory and critical care medicine (15.07.2014)
Published in American journal of respiratory and critical care medicine (15.07.2014)
Get full text
Journal Article
Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1
Lopes, Carla A.M, Prosser, Suzanna L, Romio, Leila, Hirst, Robert A, O'Callaghan, Chris, Woolf, Adrian S, Fry, Andrew M
Published in Journal of cell science (15.02.2011)
Published in Journal of cell science (15.02.2011)
Get full text
Journal Article
Ciliated air-liquid cultures as an aid to diagnostic testing of primary ciliary dyskinesia
Hirst, Robert A, Rutman, Andrew, Williams, Gwyneth, O'Callaghan, Chris
Published in Chest (01.12.2010)
Published in Chest (01.12.2010)
Get more information
Journal Article
Higher throughput drug screening for rare respiratory diseases: readthrough therapy in primary ciliary dyskinesia
Lee, Dani Do Hyang, Cardinale, Daniela, Nigro, Ersilia, Butler, Colin R, Rutman, Andrew, Fassad, Mahmoud R, Hirst, Robert A, Moulding, Dale, Agrotis, Alexander, Forsythe, Elisabeth, Peckham, Daniel, Robson, Evie, Smith, Claire M, Somavarapu, Satyanarayana, Beales, Philip L, Hart, Stephen L, Janes, Sam M, Mitchison, Hannah M, Ketteler, Robin, Hynds, Robert E, O'Callaghan, Christopher
Published in The European respiratory journal (01.10.2021)
Published in The European respiratory journal (01.10.2021)
Get full text
Journal Article
NADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma
Wan, Wing-Yan Heidi, Hollins, Fay, Haste, Louise, Woodman, Lucy, Hirst, Robert A, Bolton, Sarah, Gomez, Edith, Sutcliffe, Amanda, Desai, Dhananjay, Chachi, Latifa, Mistry, Vijay, Szyndralewiez, Cédric, Wardlaw, Andrew, Saunders, Ruth, O'Callaghan, Christopher, Andrew, Peter W, Brightling, Christopher E
Published in Chest (01.06.2016)
Published in Chest (01.06.2016)
Get more information
Journal Article
Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects
Onoufriadis, Alexandros, Shoemark, Amelia, Schmidts, Miriam, Patel, Mitali, Jimenez, Gina, Liu, Hui, Thomas, Biju, Dixon, Mellisa, Hirst, Robert A, Rutman, Andrew, Burgoyne, Thomas, Williams, Christopher, Scully, Juliet, Bolard, Florence, Lafitte, Jean-Jacques, Beales, Philip L, Hogg, Claire, Yang, Pinfen, Chung, Eddie M K, Emes, Richard D, O'Callaghan, Christopher, Bouvagnet, Patrice, Mitchison, Hannah M
Published in Human molecular genetics (01.07.2014)
Published in Human molecular genetics (01.07.2014)
Get full text
Journal Article
Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice
Dessing, Mark C, Hirst, Robert A, de Vos, Alex F, van der Poll, Tom
Published in PloS one (24.11.2009)
Published in PloS one (24.11.2009)
Get full text
Journal Article
Streptococcus pneumoniae Deficient in Pneumolysin or Autolysin Has Reduced Virulence in Meningitis
Hirst, Robert A., Gosai, Bejal, Rutman, Andrew, Guerin, Christopher J., Nicotera, Pierluigi, Andrew, Peter W., O'Callaghan, Christopher
Published in The Journal of infectious diseases (01.03.2008)
Published in The Journal of infectious diseases (01.03.2008)
Get full text
Journal Article
RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells
Lagah, Sunil, Tan, I-Li, Radhakrishnan, Priya, Hirst, Robert A, Ward, Jennifer H, O'Callaghan, Chris, Smith, Stuart J, Stevens, Malcolm F G, Grundy, Richard G, Rahman, Ruman
Published in PloS one (15.01.2014)
Published in PloS one (15.01.2014)
Get full text
Journal Article
Ciliated cultures from patients with primary ciliary dyskinesia do not produce nitric oxide or inducible nitric oxide synthase during early infection
Smith, Claire M, Fadaee-Shohada, Mina J, Sawhney, Rounak, Baker, Norman, Williams, Gwyneth, Hirst, Robert A, Andrew, Peter W, O'Callaghan, Christopher
Published in Chest (01.11.2013)
Published in Chest (01.11.2013)
Get more information
Journal Article