Inflammation drives pathogenesis of early intestinal failure-associated liver disease
Fligor, Scott C., Tsikis, Savas T., Hirsch, Thomas I., Jain, Ashish, Sun, Liang, Rockowitz, Shira, Gura, Kathleen M., Puder, Mark
Published in Scientific reports (20.02.2024)
Published in Scientific reports (20.02.2024)
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Journal Article
Direct thrombin inhibitors as alternatives to heparin to preserve lung growth and function in a murine model of compensatory lung growth
Tsikis, Savas T., Hirsch, Thomas I., Fligor, Scott C., Pan, Amy, Joiner, Malachi M., Devietro, Angela, Mitchell, Paul D., Kishikawa, Hiroko, Gura, Kathleen M., Puder, Mark
Published in Scientific reports (07.12.2022)
Published in Scientific reports (07.12.2022)
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Journal Article
Fat digestion using RELiZORB in children with short bowel syndrome who are dependent on parenteral nutrition: Protocol for a 90-day, phase 3, open labeled study
Tsikis, Savas T, Fligor, Scott C, Mitchell, Paul D, Hirsch, Thomas I, Carbeau, Sarah, First, Eric, Loring, Greta, Rudie, Coral, Freedman, Steven D, Martin, Camilia R, Gura, Kathleen M, Puder, Mark
Published in PloS one (01.03.2023)
Published in PloS one (01.03.2023)
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Journal Article
A medium-chain fatty acid analogue prevents hepatosteatosis and decreases inflammatory lipid metabolites in a murine model of parenteral nutrition-induced hepatosteatosis
Cho, Bennet S, Fligor, Scott C, Fell, Gillian L, Secor, Jordan D, Tsikis, Savas T, Pan, Amy, Yu, Lumeng J, Ko, Victoria H, Dao, Duy T, Anez-Bustillos, Lorenzo, Hirsch, Thomas I, Lund, Jenny, Rustan, Arild C, Fraser, David A, Gura, Kathleen M, Puder, Mark
Published in PloS one (01.12.2023)
Published in PloS one (01.12.2023)
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Journal Article
Current and emerging adjuvant therapies in biliary atresia
Fligor, Scott C, Hirsch, Thomas I, Tsikis, Savas T, Adeola, Andrew, Puder, Mark
Published in Frontiers in pediatrics (14.10.2022)
Published in Frontiers in pediatrics (14.10.2022)
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Journal Article
A pneumonectomy model to study flow-induced pulmonary hypertension and compensatory lung growth
Tsikis, Savas T., Klouda, Timothy, Hirsch, Thomas I., Fligor, Scott C., Liu, Tiffany, Kim, Yunhye, Pan, Amy, Quigley, Mikayla, Mitchell, Paul D., Puder, Mark, Yuan, Ke
Published in Cell reports methods (23.10.2023)
Published in Cell reports methods (23.10.2023)
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Journal Article
Intravenous lipid emulsions designed to meet preterm infant requirements increase plasma and tissue levels of docosahexaenoic acid and arachidonic acid in mice
Fligor, Scott C., Tsikis, Savas T., Hirsch, Thomas I., Quigley, Mikayla, Pan, Amy, Kishikawa, Hiroko, Mitchell, Paul D., Gura, Kathleen M., Puder, Mark
Published in Clinical nutrition (Edinburgh, Scotland) (01.10.2024)
Published in Clinical nutrition (Edinburgh, Scotland) (01.10.2024)
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Pla2g5 contributes to viral-like-induced lung inflammation through macrophage proliferation and LA/Ffar1 lung cell recruitment
Koganesawa, Masaya, Dwyer, Daniel F, Alhallak, Kinan, Nagai, Jun, Zaleski, Kendall, Samuchiwal, Sachin, Hiroaki, Hayashi, Nishida, Airi, Hirsch, Thomas I, Brennan, Patrick J, Puder, Mark, Balestrieri, Barbara
Published in Immunology (01.05.2024)
Published in Immunology (01.05.2024)
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Journal Article
A Medium-Chain Fatty Acid Analogue Prevents Intestinal Failure–Associated Liver Disease in Preterm Yorkshire Piglets
Fligor, Scott C., Tsikis, Savas T., Hirsch, Thomas I., Pan, Amy, Moskowitzova, Kamila, Rincon-Cruz, Lorena, Whitlock, Ashlyn E., Mitchell, Paul D., Nedder, Arthur P., Gura, Kathleen M., Fraser, David A., Puder, Mark
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2023)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2023)
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Journal Article
A Digestive Cartridge Reduces Parenteral Nutrition Dependence and Increases Bowel Growth in a Piglet Short Bowel Model
Tsikis, Savas T, Fligor, Scott C, Hirsch, Thomas I, Mitchell, Paul D, Pan, Amy, Moskowitzova, Kamila, Whitlock, Ashlyn E, Loring, Greta, First, Eric, Nedder, Arthur, Gura, Kathleen M, Puder, Mark
Published in Annals of surgery (01.10.2023)
Published in Annals of surgery (01.10.2023)
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Journal Article
Direct thrombin inhibitors fail to reverse the negative effects of heparin on lung growth and function after murine left pneumonectomy
Tsikis, Savas T, Hirsch, Thomas I, Klouda, Timothy, Fligor, Scott C, Pan, Amy, Joiner, Malachi M, Wang, Sarah Z, Quigley, Mikayla, Devietro, Angela, Mitchell, Paul D, Kishikawa, Hiroko, Yuan, Ke, Puder, Mark
Published in American journal of physiology. Lung cellular and molecular physiology (01.03.2024)
Published in American journal of physiology. Lung cellular and molecular physiology (01.03.2024)
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Journal Article
Absorption of an engineered medium-chain fatty acid analogue in two short bowel syndrome minipig models
Fligor, Scott C, Tsikis, Savas T, Hirsch, Thomas I, Pan, Amy, Mitchell, Paul D, Quigley, Mikayla, Carbeau, Sarah, Nedder, Arthur, Gura, Kathleen M, Puder, Mark
Published in JPEN. Journal of parenteral and enteral nutrition (01.11.2023)
Published in JPEN. Journal of parenteral and enteral nutrition (01.11.2023)
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Journal Article
Administration of 4% tetrasodium EDTA lock solution and central venous catheter complications in high-risk pediatric patients with intestinal failure: A retrospective cohort study
Hirsch, Thomas I, Fligor, Scott C, Tsikis, Savas T, Mitchell, Paul D, DeVietro, Angela, Carbeau, Sarah, Wang, Sarah Z, McClelland, Jennifer, Carey, Alexandra N, Gura, Kathleen M, Puder, Mark
Published in JPEN. Journal of parenteral and enteral nutrition (01.07.2024)
Published in JPEN. Journal of parenteral and enteral nutrition (01.07.2024)
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Journal Article
Ethanol lock therapy increases mechanical catheter complications in a pediatric intestinal failure population: A retrospective cohort study
Fligor, Scott C, Hirsch, Thomas I, Tsikis, Savas T, Joiner, Malachi M, Mitchell, Paul D, Carbeau, Sarah, McClelland, Jennifer, Carey, Alexandra, Gura, Kathleen M, Puder, Mark
Published in JPEN. Journal of parenteral and enteral nutrition (01.07.2023)
Published in JPEN. Journal of parenteral and enteral nutrition (01.07.2023)
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Journal Article
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
Barrachina, Maria N, Pernes, Gerard, Becker, Isabelle C, Allaeys, Isabelle, Hirsch, Thomas I, Groeneveld, Dafna J, Khan, Abdullah O, Freire, Daniela, Guo, Karen, Carminita, Estelle, Morgan, Pooranee K, Collins, Thomas J C, Mellett, Natalie A, Wei, Zimu, Almazni, Ibrahim, Italiano, Joseph E, Luyendyk, James, Meikle, Peter J, Puder, Mark, Morgan, Neil V, Boilard, Eric, Murphy, Andrew J, Machlus, Kellie R
Published in Nature cardiovascular research (01.08.2023)
Published in Nature cardiovascular research (01.08.2023)
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Journal Article
Smooth muscle Cxcl12 activation is associated with vascular remodeling in flow-induced pulmonary hypertension
Klouda, Timothy, Tsikis, Savas T, Hirsch, Thomas I, Kim, Yunhye, Liu, Tiffany, Friehs, Ingeborg, Shyy, John Y-J, Visner, Gary, Raby, Benjamin A, Puder, Mark, Yuan, Ke
Published in bioRxiv (10.09.2024)
Published in bioRxiv (10.09.2024)
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Journal Article
Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
Barrachina, Maria N, Pernes, Gerard, Becker, Isabelle C, Allaeys, Isabelle, Hirsch, Thomas I, Groeneveld, Dafna J, Abdullah Obaid Khan, Freire, Daniela, Guo, Karen, Carminita, Estelle, Morgan, Pooranee K, Collins, Thomas J, Mellett, Natalie, Zimu Wei, Ibrahim Almazni, Italiano, Joseph E, Luyendyk, James, Meikle, Peter J, Puder, Mark, Morgan, Neil V, Boilard, Eric, Murphy, Andrew J, Machlus, Kellie R
Published in bioRxiv (12.02.2023)
Published in bioRxiv (12.02.2023)
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