Do STAT3 inhibitors have potential in the future for cancer therapy?
Wong, Andrea L A, Hirpara, Jayshree L, Pervaiz, Shazib, Eu, Jie-Qing, Sethi, Gautam, Goh, Boon-Cher
Published in Expert opinion on investigational drugs (03.08.2017)
Published in Expert opinion on investigational drugs (03.08.2017)
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Journal Article
Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors
Lee, Matilda, Hirpara, Jayshree L., Eu, Jie-Qing, Sethi, Gautam, Wang, Lingzhi, Goh, Boon-Cher, Wong, Andrea L.
Published in Redox biology (01.07.2019)
Published in Redox biology (01.07.2019)
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Journal Article
Cellular senescence: Silent operator and therapeutic target in cancer
Ramu, Deepika, Shan, Teoh Wei, Hirpara, Jayshree L, Pervaiz, Shazib
Published in IUBMB life (01.03.2021)
Published in IUBMB life (01.03.2021)
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Journal Article
Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance
Hirpara, Jayshree, Eu, Jie Qing, Tan, Joanna Kia Min, Wong, Andrea L., Clement, Marie-Veronique, Kong, Li Ren, Ohi, Naoto, Tsunoda, Takeshi, Qu, Jianhua, Goh, Boon Cher, Pervaiz, Shazib
Published in Redox biology (01.07.2019)
Published in Redox biology (01.07.2019)
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Journal Article
Identification of a novel catalytic inhibitor of topoisomerase II alpha that engages distinct mechanisms in p53wt or p53−/− cells to trigger G2/M arrest and senescence
Lee, Soo Fern, Hirpara, Jayshree L., Qu, Jianhua, Yadav, Sanjiv K., Sachaphibulkij, Karishma, Pervaiz, Shazib
Published in Cancer letters (01.02.2022)
Published in Cancer letters (01.02.2022)
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Journal Article
Manganese Superoxide Dismutase Expression Regulates the Switch Between an Epithelial and a Mesenchymal-Like Phenotype in Breast Carcinoma
Loo, Ser Yue, Hirpara, Jayshree L, Pandey, Vijay, Tan, Tuan Zea, Yap, Celestial T, Lobie, Peter E, Thiery, Jean Paul, Goh, Boon Cher, Pervaiz, Shazib, Clément, Marie-Véronique, Kumar, Alan Prem
Published in Antioxidants & redox signaling (20.08.2016)
Published in Antioxidants & redox signaling (20.08.2016)
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Journal Article
A novel MTORC2-AKT-ROS axis triggers mitofission and mitophagy-associated execution of colorectal cancer cells upon drug-induced activation of mutant KRAS
Iskandar, Kartini, Foo, Jonathan, Liew, Angeline Qiu Xia, Zhu, Haiyuxin, Raman, Deepika, Hirpara, Jayshree L., Leong, Yan Yi, Babak, Maria V., Kirsanova, Anna A., Armand, Anne-Sophie, Oury, Franck, Bellot, Gregory, Pervaiz, Shazib
Published in Autophagy (02.06.2024)
Published in Autophagy (02.06.2024)
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Journal Article
Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc
Raman, Deepika, Chong, Stephen J.F., Iskandar, Kartini, Hirpara, Jayshree L., Pervaiz, Shazib
Published in Redox biology (01.07.2020)
Published in Redox biology (01.07.2020)
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Journal Article
Mitochondrial chaperon TNF-receptor- associated protein 1 as a novel apoptotic regulator conferring susceptibility to Pneumocystis jirovecii pneumonia
Amali, Aseervatham Anusha, Paramasivam, Kathirvel, Huang, Chiung Hui, Joshi, Abhinav, Hirpara, Jayshree L, Ravikumar, Sharada, Sam, Qi Hui, Tan, Rachel Ying Min, Tan, Zhaohong, Kumar, Dilip, Neckers, Leonard M, Pervaiz, Shazib, Foo, Roger, Chan, Candice Y Y, Zhu, Jin, Lee, Cheryl, Chai, Louis Yi Ann
Published in Frontiers in immunology (19.08.2024)
Published in Frontiers in immunology (19.08.2024)
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Journal Article
Correction: Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation
Wong, Chew Hooi, Iskandar, Kartini Bte, Yadav, Sanjiv Kumar, Hirpara, Jayshree L, Loh, Thomas, Pervaiz, Shazib
Published in PloS one (08.07.2016)
Published in PloS one (08.07.2016)
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Journal Article
Author Correction: METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
Lee, Bernice Woon Li, Chuah, You Heng, Yoon, Jeehyun, Grinchuk, Oleg V., Liang, Yajing, Hirpara, Jayshree L., Shen, Yating, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M., Yeo, Tseng Tsai, Wong, Andrea Li Ann, Teo, Kejia, Nga, Vincent Diong Weng, Tan, Bryce Wei Quan, Suda, Toshio, Toh, Tan Boon, Pervaiz, Shazib, Lin, Zhewang, Ong, Derrick Sek Tong
Published in Cell death & disease (31.07.2024)
Published in Cell death & disease (31.07.2024)
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Journal Article
METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity
Lee, Bernice Woon Li, Chuah, You Heng, Yoon, Jeehyun, Grinchuk, Oleg V., Liang, Yajing, Hirpara, Jayshree L., Shen, Yating, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M., Yeo, Tseng Tsai, Wong, Andrea Li Ann, Teo, Kejia, Nga, Vincent Diong Weng, Tan, Bryce Wei Quan, Suda, Toshio, Toh, Tan Boon, Pervaiz, Shazib, Lin, Zhewang, Ong, Derrick Sek Tong
Published in Cell death & disease (14.05.2024)
Published in Cell death & disease (14.05.2024)
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Journal Article
The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity
Velaithan, Rathiga, Kang, Jia, Hirpara, Jayshree L., Loh, Thomas, Goh, Boon Cher, Le Bras, Morgane, Brenner, Catherine, Clement, Marie-Veronique, Pervaiz, Shazib
Published in Blood (09.06.2011)
Published in Blood (09.06.2011)
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Journal Article
Superoxide induced inhibition of death receptor signaling is mediated via induced expression of apoptosis inhibitory protein cFLIP
Hirpara, Jayshree L., Subramaniam, Kothandharaman, Bellot, Gregory, Qu, Jianhua, Seah, Serena, Loh, Thomas, Tucker-Kellogg, Lisa, Clement, Marie-Veronique, Pervaiz, Shazib
Published in Redox biology (01.02.2020)
Published in Redox biology (01.02.2020)
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Journal Article
FLIP: A flop for execution signals
Subramaniam, Kothandharaman, Hirpara, Jayshree L, Tucker-Kellogg, Lisa, Tucker-Kellogg, Greg, Pervaiz, Shazib
Published in Cancer letters (28.05.2013)
Published in Cancer letters (28.05.2013)
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