Overexpression of GPR40 in Pancreatic β-Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice
NAGASUMI, Kae, ESAKI, Ritsuko, TAKEUCHI, Koji, ODAKA, Hiroyuki, KAISHO, Yoshihiko, IWACHIDOW, Kimihiko, YASUHARA, Yoshitaka, OGI, Kazuhiro, TANAKA, Hideyuki, NAKATA, Mitsugu, YANO, Takashi, SHIMAKAWA, Kozo, TAKETOMI, Shigehisa
Published in Diabetes (New York, N.Y.) (01.05.2009)
Published in Diabetes (New York, N.Y.) (01.05.2009)
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Chronic administration of alogliptin, a novel, potent, and highly selective dipeptidyl peptidase-4 inhibitor, improves glycemic control and beta-cell function in obese diabetic ob/ob mice
Moritoh, Yusuke, Takeuchi, Koji, Asakawa, Tomoko, Kataoka, Osamu, Odaka, Hiroyuki
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Published in European journal of pharmacology (07.07.2008)
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Activation of Human Peroxisome Proliferator-Activated Receptor (PPAR) Subtypes by Pioglitazone
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Published in Biochemical and biophysical research communications (30.11.2000)
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Anti-obesity effects of a mixture of thiamin, arginine, caffeine, and citric acid in non-insulin dependent diabetic KK mice
Muroyama, K. (Takeda Food Products Ltd., Itami, Hyogo (Japan)), Murosaki, S, Yamamoto, Y, Odaka, H, Chung, H.C, Miyoshi, M
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Studies on Non-Thiazolidinedione Antidiabetic Agents. 3. Preparation and Biological Activity of the Metabolites of TAK-559
Imoto, Hiroshi, Matsumoto, Mitsuharu, Odaka, Hiroyuki, Sakamoto, Junichi, Kimura, Hiroyuki, Nonaka, Masami, Kiyota, Yutaka, Momose, Yu
Published in Chemical & pharmaceutical bulletin (2004)
Published in Chemical & pharmaceutical bulletin (2004)
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The dipeptidyl peptidase-4 inhibitor alogliptin in combination with pioglitazone improves glycemic control, lipid profiles, and increases pancreatic insulin content in ob/ob mice
Moritoh, Yusuke, Takeuchi, Koji, Asakawa, Tomoko, Kataoka, Osamu, Odaka, Hiroyuki
Published in European journal of pharmacology (14.01.2009)
Published in European journal of pharmacology (14.01.2009)
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Studies on Non-Thiazolidinedione Antidiabetic Agents. 3. 1, 2) Preparation and Biological Activity of the Metabolites of TAK-559
Hiroshi IMOTO, Mitsuharu MATSUMOTO, Hiroyuki ODAKA, Junichi SAKAMOTO, Hiroyuki KIMURA, Masami NONAKA, Yutaka KIYOTA, Yu MOMOSE
Published in Chemical & Pharmaceutical Bulletin (2004)
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Published in Chemical & Pharmaceutical Bulletin (2004)
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Effects of Dietary Fructose or Glucose on Triglyceride Production and Lipogenic Enzyme Activities in the Liver of Wistar Fatty Rats, an Animal Model of NIDDM
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Published in Endocrine Journal (1997)
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Novel 5-Substituted 2,4-Thiazolidinedione and 2,4-Oxazolidinedione Derivatives as Insulin Sensitizers with Antidiabetic Activities
Momose, Yu, Maekawa, Tsuyoshi, Yamano, Tohru, Kawada, Mitsuru, Odaka, Hiroyuki, Ikeda, Hitoshi, Sohda, Takashi
Published in Journal of medicinal chemistry (28.03.2002)
Published in Journal of medicinal chemistry (28.03.2002)
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Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes
IHARA, Y, TOYOKUNI, S, UCHIDA, K, ODAKA, H, TANAKA, T, IKEDA, H, HIAI, H, SEINO, Y, YAMADA, Y
Published in Diabetes (New York, N.Y.) (01.04.1999)
Published in Diabetes (New York, N.Y.) (01.04.1999)
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A novel dipeptidyl peptidase-4 inhibitor, alogliptin (SYR-322), is effective in diabetic rats with sulfonylurea-induced secondary failure
Asakawa, Tomoko, Moritoh, Yusuke, Kataoka, Osamu, Suzuki, Nobuhiro, Takeuchi, Koji, Odaka, Hiroyuki
Published in Life sciences (1973) (17.07.2009)
Published in Life sciences (1973) (17.07.2009)
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Allylthiamindisulfide and related compounds enhance thermogenesis with increasing noradrenaline and adrenaline secretion in rats
Oi, Y. (Kobe Women's Univ. (Japan)), Shishido, C, Wada, K, Odaka, H, Ikeda, H, Iwai, K
Published in Journal of Nutritional Science and Vitaminology (01.10.1999)
Published in Journal of Nutritional Science and Vitaminology (01.10.1999)
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Antiobesity and antidiabetic actions of a new potent disaccharidase inhibitor in genetically obese-diabetic mice, KKAy
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Published in Journal of Nutritional Science and Vitaminology (1992)
Published in Journal of Nutritional Science and Vitaminology (1992)
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Marked reduction of pancreatic insulin content in male ventromedial hypothalamic-lesioned spontaneously non-insulin-dependent diabetic (Goto-Kakizaki) rats
Keno, Y, Tokunaga, K, Fujioka, S, Kobatake, T, Kotani, K, Yoshida, S, Nishida, M, Shimomura, I, Matsuo, T, Odaka, H
Published in Metabolism, clinical and experimental (01.01.1994)
Published in Metabolism, clinical and experimental (01.01.1994)
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Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin
OGAWA, Y, MASUZAKI, H, ODAKA, H, KASUGA, H, FUJISAWA, Y, INOUE, G, NISHIMURA, H, YOSHIMASA, Y, NAKAO, K, HOSODA, K, AIZAWA-ABE, M, SUGA, J, SUDA, M, EBIHARA, K, IWAI, H, MATSUOKA, N, SATOH, N
Published in Diabetes (New York, N.Y.) (01.09.1999)
Published in Diabetes (New York, N.Y.) (01.09.1999)
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Overexpression of GPR40 in Pancreatic [beta]-Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice
Nagasumi, Kae, Esaki, Ritsuko, Iwachidow, Kimihiko, Yasuhara, Yoshitaka, Ogi, Kazuhiro, Tanaka, Hideyuki, Nakata, Mitsugu, Yano, Takashi, Shimakawa, Kozo, Taketomi, Shigehisa, Takeuchi, Koji, Odaka, Hiroyuki, Kaisho, Yoshihiko
Published in Diabetes (New York, N.Y.) (01.05.2009)
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Published in Diabetes (New York, N.Y.) (01.05.2009)
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