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Published in PloS one (04.02.2014)
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A New Water‐soluble Camptothecin Derivative, DX‐8951f, Exhibits Potent Antitumor Activity against Human Tumors in vitro and in vivo
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Human Telomerase Exists in Two Distinct Active Complexes In Vivo
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Published in Journal of medicinal chemistry (27.11.2019)
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Synthesis and Structure-Activity Relationships of Novel 2', 2'-Difluoro Analogues of Docetaxel
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Published in Chemical & pharmaceutical bulletin (01.11.1997)
Published in Chemical & pharmaceutical bulletin (01.11.1997)
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Potent and Selective PTDSS1 Inhibitors Induce Collateral Lethality in Cancers with PTDSS2 Deletion
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Published in Cancer research (Chicago, Ill.) (02.11.2022)
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RNA interference activity of single-stranded oligonucleotides linked between the passenger strand and the guide strand with an aryl phosphate linker
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Published in Nucleosides, nucleotides & nucleic acids (2021)
Published in Nucleosides, nucleotides & nucleic acids (2021)
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Design of 2'-O-methyl RNA and DNA double-stranded oligonucleotides: naturally-occurring nucleotide components with strong RNA interference gene expression inhibitory activity
Koizumi, Makoto, Hirota, Yasuhide, Nakayama, Makiko, Tamura, Masakazu, Obuchi, Wataru, Kurimoto, Akiko, Tsuchida, Hiroshi, Maeda, Hiroaki
Published in Nucleosides, nucleotides & nucleic acids (20.02.2020)
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Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma
Koul, Dimpy, Wang, Shuzhen, Wu, Shaofang, Saito, Norihiko, Zheng, Siyuan, Gao, Feng, Kaul, Isha, Setoguchi, Masaki, Nakayama, Kiyoshi, Koyama, Kumiko, Shiose, Yoshinobu, Sulman, Erik P, Hirota, Yasuhide, Yung, W K Alfred
Published in Oncotarget (28.03.2017)
Published in Oncotarget (28.03.2017)
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Synthesis and Evaluation of Water-Soluble Non-Prodrug Analogs of Docetaxel Bearing sec-Aminoethyl Group at the C-10 Position
UOTO, Kouichi, TAKENOSHITA, Haruhiro, YOSHINO, Toshiharu, HIROTA, Yasuhide, ANDO, Shuichi, MITSUI, Ikuo, TERASAWA, Hirofumi, SOGA, Tsunehiko
Published in Chemical & pharmaceutical bulletin (01.05.1998)
Published in Chemical & pharmaceutical bulletin (01.05.1998)
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ATPS-46PRECLINICAL THERAPEUTIC EFFICACY OF A NOVEL BLOOD-BRAIN BARRIER-PENETRANT DUAL PI3K/MTOR INHIBITOR WITH PREFERENTIAL RESPONSE IN PI3K/PTEN MUTANT GLIOMA
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Published in Neuro-oncology (Charlottesville, Va.) (01.11.2015)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2015)
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Deoxyribonucleoside-triphosphate imbalance death: Deoxyadenosine-induced dNTP imbalance and DNA double strand breaks in mouse FM3A cells and the mechanism of cell death
Yoshioka, Akiko, Tanaka, Shohei, Hiraoka, Osamu, Koyama, Yuji, Hirota, Yasuhide, Wataya, Yusuke
Published in Biochemical and biophysical research communications (15.07.1987)
Published in Biochemical and biophysical research communications (15.07.1987)
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Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
Kawato, Y, Aonuma, M, Hirota, Y, Kuga, H, Sato, K
Published in Cancer research (Chicago, Ill.) (15.08.1991)
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Published in Cancer research (Chicago, Ill.) (15.08.1991)
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