Pharmacological Characterization of a New Antimuscarinic Agent, Solifenacin Succinate, in Comparison with Other Antimuscarinic Agents
Ohtake, Akiyoshi, Saitoh, Chikashi, Yuyama, Hironori, Ukai, Masashi, Okutsu, Hiroko, Noguchi, Yukiko, Hatanaka, Toshiki, Suzuki, Masanori, Sato, Shuichi, Sasamata, Masao, Miyata, Keiji
Published in Biological & pharmaceutical bulletin (2007)
Published in Biological & pharmaceutical bulletin (2007)
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Journal Article
Tamsulosin Potently and Selectively Antagonizes Human Recombinant α1A/1D-Adrenoceptors: Slow Dissociation from the α1A-Adrenoceptor May Account for Selectivity for α1A-Adrenoceptor over α1B-Adrenoceptor Subtype
Sato, Shuichi, Hatanaka, Toshiki, Yuyama, Hironori, Ukai, Masashi, Noguchi, Yukiko, Ohtake, Akiyoshi, Taguchi, Katsunari, Sasamata, Masao, Miyata, Keiji
Published in Biological and Pharmaceutical Bulletin (01.01.2012)
Published in Biological and Pharmaceutical Bulletin (01.01.2012)
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Journal Article
Tamsulosin Potently and Selectively Antagonizes Human Recombinant .ALPHA.1A/1D-Adrenoceptors: Slow Dissociation from the .ALPHA.1A-Adrenoceptor May Account for Selectivity for .ALPHA.1A-Adrenoceptor over .ALPHA.1B-Adrenoceptor Subtype
Sato, Shuichi, Hatanaka, Toshiki, Yuyama, Hironori, Ukai, Masashi, Noguchi, Yukiko, Ohtake, Akiyoshi, Taguchi, Katsunari, Sasamata, Masao, Miyata, Keiji
Published in Biological & pharmaceutical bulletin (2012)
Published in Biological & pharmaceutical bulletin (2012)
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Journal Article
Comparison of muscarinic receptor selectivity of solifenacin and oxybutynin in the bladder and submandibular gland of muscarinic receptor knockout mice
Ito, Yoshihiko, Oyunzul, Luvsandorj, Yoshida, Akira, Fujino, Tomomi, Noguchi, Yukiko, Yuyama, Hironori, Ohtake, Akiyoshi, Suzuki, Masanori, Sasamata, Masao, Matsui, Minoru, Yamada, Shizuo
Published in European journal of pharmacology (01.08.2009)
Published in European journal of pharmacology (01.08.2009)
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Journal Article
In vitro and in vivo effects of endothelin-1 and YM598, a selective endothelin ETA receptor antagonist, on the lower urinary tract
Ukai, Masashi, Yuyama, Hironori, Fujimori, Akira, Koakutsu, Akiko, Sanagi, Masanao, Ohtake, Akiyoshi, Sato, Shuichi, Sudoh, Katsumi, Sasamata, Masao, Miyata, Keiji
Published in European journal of pharmacology (12.02.2008)
Published in European journal of pharmacology (12.02.2008)
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Journal Article
Effects of solifenacin succinate (YM905) on detrusor overactivity in conscious cerebral infarcted rats
Suzuki, Masanori, Ohtake, Akiyoshi, Yoshino, Taiji, Yuyama, Hironori, Hayashi, Aska, Ukai, Masashi, Okutsu, Hiroko, Noguchi, Yukiko, Sato, Shuichi, Sasamata, Masao
Published in European journal of pharmacology (04.04.2005)
Published in European journal of pharmacology (04.04.2005)
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Journal Article
In vivo studies on the effects of α1-adrenoceptor antagonists on pupil diameter and urethral tone in rabbits
Michel, Martin C., Okutsu, Hiroko, Noguchi, Yukiko, Suzuki, Masanori, Ohtake, Akiyoshi, Yuyama, Hironori, Yanai-Inamura, Hiroko, Ukai, Masashi, Watanabe, Mai, Someya, Akiyoshi, Sasamata, Masao
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.02.2006)
Published in Naunyn-Schmiedeberg's archives of pharmacology (01.02.2006)
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Journal Article
Pharmacological characterization of YM598, an orally active and highly potent selective endothelin ETA receptor antagonist
YUYAMA, Hironori, SANAGI, Masanao, KOAKUTSU, Akiko, MORI, Mikiko, FUJIMORI, Akira, HARADA, Hironori, SUDOH, Katsumi, MIYATA, Keiji
Published in European journal of pharmacology (30.09.2003)
Published in European journal of pharmacology (30.09.2003)
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Journal Article
The orally active nonpeptide selective endothelin ETA receptor antagonist YM598 prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats
YUYAMA, Hironori, FUJIMORI, Akira, SANAGI, Masanao, KOAKUTSU, Akiko, SUDOH, Katsumi, SASAMATA, Masao, MIYATA, Keiji
Published in European journal of pharmacology (02.08.2004)
Published in European journal of pharmacology (02.08.2004)
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Journal Article
Potentiation of Muscarinic M 3 Receptor Activation through a New Allosteric Site with a Novel Positive Allosteric Modulator ASP8302
Okimoto, Risa, Ino, Katsutoshi, Ishizu, Kenichiro, Takamatsu, Hajime, Sakamoto, Kazuyuki, Yuyama, Hironori, Fuji, Hideyoshi, Someya, Akiyoshi, Ohtake, Akiyoshi, Ishigami, Takao, Masuda, Noriyuki, Takeda, Masahiro, Kajioka, Shunichi, Yoshimura, Naoki
Published in The Journal of pharmacology and experimental therapeutics (01.10.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2021)
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Journal Article
Potentiation of Muscarinic M3 Receptor Activation through a New Allosteric Site with a Novel Positive Allosteric Modulator ASP8302
Okimoto, Risa, Ino, Katsutoshi, Ishizu, Kenichiro, Takamatsu, Hajime, Sakamoto, Kazuyuki, Yuyama, Hironori, Fuji, Hideyoshi, Someya, Akiyoshi, Ohtake, Akiyoshi, Ishigami, Takao, Masuda, Noriyuki, Takeda, Masahiro, Kajioka, Shunichi, Yoshimura, Naoki
Published in The Journal of pharmacology and experimental therapeutics (01.10.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2021)
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Journal Article
P3-140 YM598, a selective ETA receptor antagonist, ameliorates hypoxemia and lung dysfunction in guinea pigs and rats with chronic obstructive pulmonary disease(COPD)
Akira Fujimori, Hironori Yuyama, Akiko Koakutsu, Masanao Sanagi, Masao Sasamata, Masamichi Okada, Keiji Miyata
Published in Journal of Pharmacological Sciences (2007)
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Published in Journal of Pharmacological Sciences (2007)
Journal Article
Effect of single oral administration of YM598, a novel selective endothelin ETA receptor antagonist, on blood pressure in normotensive and hypertensive rats
Yuyama, Hironori, Sonoda, Rie, Shibasaki, Kumiko, Fujimori, Akira, Sudoh, Katsumi, Sasamata, Masao, Miyata, Keiji
Published in Vascular pharmacology (01.02.2004)
Published in Vascular pharmacology (01.02.2004)
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Journal Article
O2F1-3 Characterization of muscarinic receptor(mR)binding after oral administration of anticholinergic agents in muscarinic M2 knockout mice
Oyunzul Luvsandorj, Tomomi Fujino, Masanao Seki, Yukiko Noguchi, Hironori Yuyama, Akiyoshi Ohtake, Masanori Suzuki, Masao Sasamata, Minoru Matsui, Shizuo Yamada
Published in Journal of Pharmacological Sciences (2007)
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Published in Journal of Pharmacological Sciences (2007)
Journal Article
Muscarinic M 3 positive allosteric modulator ASP8302 enhances bladder contraction and improves voiding dysfunction in rats
Okimoto, Risa, Ino, Katsutoshi, Ishizu, Kenichiro, Takamatsu, Hajime, Sakamoto, Kazuyuki, Yuyama, Hironori, Imazumi, Katsunori, Ohtake, Akiyoshi, Masuda, Noriyuki, Takeda, Masahiro
Published in Lower urinary tract symptoms (01.07.2022)
Published in Lower urinary tract symptoms (01.07.2022)
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Journal Article
Muscarinic M3 positive allosteric modulator ASP8302 enhances bladder contraction and improves voiding dysfunction in rats
Okimoto, Risa, Ino, Katsutoshi, Ishizu, Kenichiro, Takamatsu, Hajime, Sakamoto, Kazuyuki, Yuyama, Hironori, Imazumi, Katsunori, Ohtake, Akiyoshi, Masuda, Noriyuki, Takeda, Masahiro
Published in Lower urinary tract symptoms (01.07.2022)
Published in Lower urinary tract symptoms (01.07.2022)
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Journal Article
Effect of tamsulosin on involuntary bladder contractions in conscious rats with bladder outlet obstruction
Akiyoshi Ohtake, Masashi Ukai, Hironori Yuyama, Noriko Fujiyasu, Yukiko Noguchi, Shuichi Sato, Masao Sasamata
Published in Journal of Pharmacological Sciences (2005)
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Published in Journal of Pharmacological Sciences (2005)
Journal Article
Selective ETA receptor antagonist YM598 inhibits ET-1 -induced cell signaling and cell growth in hormone refractory human prostate cancer cell line, PPC-1
Mai Watanabe, Hironori Yuyama, Akira Fujimori, Mikiko Mori, Shuichi Sato, Katsumi Sudoh, Masao Sasamata
Published in Journal of Pharmacological Sciences (2005)
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Published in Journal of Pharmacological Sciences (2005)
Journal Article