Therapeutic Application of Extracellular Vesicles-Capsulated Adeno-Associated Virus Vector via nSMase2/Smpd3 , Satellite, and Immune Cells in Duchenne Muscular Dystrophy
Matsuzaka, Yasunari, Hirai, Yukihiko, Hashido, Kazuo, Okada, Takashi
Published in International journal of molecular sciences (28.01.2022)
Published in International journal of molecular sciences (28.01.2022)
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Microstructure and Tensile Properties of Sn-Ag-Cu-In-Sb Solder
Morofushi, Hayato, Shohji, Ikuo, Hirai, Yukihiko, Oomori, Kouki
Published in Materials science forum (05.01.2021)
Published in Materials science forum (05.01.2021)
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High-Level Expression of Alkaline Phosphatase by Adeno-Associated Virus Vector Ameliorates Pathological Bone Structure in a Hypophosphatasia Mouse Model
Nakamura-Takahashi, Aki, Tanase, Toshiki, Matsunaga, Satoru, Shintani, Seikou, Abe, Shinichi, Nitahara-Kasahara, Yuko, Watanabe, Atsushi, Hirai, Yukihiko, Okada, Takashi, Yamaguchi, Akira, Kasahara, Masataka
Published in Calcified tissue international (01.06.2020)
Published in Calcified tissue international (01.06.2020)
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Intrathecal AAV Serotype 9-mediated Delivery of shRNA Against TRPV1 Attenuates Thermal Hyperalgesia in a Mouse Model of Peripheral Nerve Injury
Hirai, Takashi, Enomoto, Mitsuhiro, Kaburagi, Hidetoshi, Sotome, Shinichi, Yoshida-Tanaka, Kie, Ukegawa, Madoka, Kuwahara, Hiroya, Yamamoto, Mariko, Tajiri, Mio, Miyata, Haruka, Hirai, Yukihiko, Tominaga, Makoto, Shinomiya, Kenichi, Mizusawa, Hidehiro, Okawa, Atsushi, Yokota, Takanori
Published in Molecular therapy (01.02.2014)
Published in Molecular therapy (01.02.2014)
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Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector
Hironaka, Kohei, Yamazaki, Yoshiyuki, Hirai, Yukihiko, Yamamoto, Motoko, Miyake, Noriko, Miyake, Koichi, Okada, Takashi, Morita, Akio, Shimada, Takashi
Published in Scientific reports (18.08.2015)
Published in Scientific reports (18.08.2015)
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Hepatocyte Growth Factor Receptor Is a Coreceptor for Adeno-Associated Virus Type 2 Infection
KASHIWAKURA, Yuji, TAMAYOSE, Kenji, IWABUCHI, Kazuhisa, HIRAI, Yukihiko, SHIMADA, Takashi, MATSUMOTO, Kunio, NAKAMURA, Toshikazu, WATANABE, Masami, OSHIMI, Kazuo, DAIDA, Hiroyuki
Published in Journal of Virology (01.01.2005)
Published in Journal of Virology (01.01.2005)
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Highly Efficient Ultracentrifugation-free Chromatographic Purification of Recombinant AAV Serotype 9
Tomono, Taro, Hirai, Yukihiko, Okada, Hironori, Miyagawa, Yoshitaka, Adachi, Kumi, Sakamoto, Shuhei, Kawano, Yasuhiro, Chono, Hideto, Mineno, Junichi, Ishii, Akiko, Shimada, Takashi, Onodera, Masafumi, Tamaoka, Akira, Okada, Takashi
Published in Molecular therapy. Methods & clinical development (01.12.2018)
Published in Molecular therapy. Methods & clinical development (01.12.2018)
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Infectivity Assessment of Recombinant Adeno-Associated Virus and Wild-Type Adeno-Associated Virus Exposed to Various Diluents and Environmental Conditions
Tomono, Taro, Hirai, Yukihiko, Chono, Hideto, Mineno, Junichi, Ishii, Akiko, Onodera, Masafumi, Tamaoka, Akira, Okada, Takashi
Published in Human gene therapy. Part B. Methods (01.08.2019)
Published in Human gene therapy. Part B. Methods (01.08.2019)
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Ultracentrifugation-free chromatography-mediated large-scale purification of recombinant adeno-associated virus serotype 1 (rAAV1)
Tomono, Taro, Hirai, Yukihiko, Okada, Hironori, Adachi, Kumi, Ishii, Akiko, Shimada, Takashi, Onodera, Masafumi, Tamaoka, Akira, Okada, Takashi
Published in Molecular therapy. Methods & clinical development (01.01.2016)
Published in Molecular therapy. Methods & clinical development (01.01.2016)
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AAV1 Mediated Co-expression of Formylglycine-Generating Enzyme and Arylsulfatase A Efficiently Corrects Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy
Kurai, Toshiyuki, Hisayasu, Sanae, Kitagawa, Ryo, Migita, Makoto, Suzuki, Hidenori, Hirai, Yukihiko, Shimada, Takashi
Published in Molecular therapy (01.01.2007)
Published in Molecular therapy (01.01.2007)
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Intraperitoneal AAV9-shRNA inhibits target expression in neonatal skeletal and cardiac muscles
Mayra, Azat, Tomimitsu, Hiroyuki, Kubodera, Takayuki, Kobayashi, Masaki, Piao, Wenying, Sunaga, Fumiko, Hirai, Yukihiko, Shimada, Takashi, Mizusawa, Hidehiro, Yokota, Takanori
Published in Biochemical and biophysical research communications (11.02.2011)
Published in Biochemical and biophysical research communications (11.02.2011)
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Intraperitoneal Administration of AAV9-shRNA Inhibits Target Gene Expression in the Dorsal Root Ganglia of Neonatal Mice
Machida, Akira, Kuwahara, Hiroya, Mayra, Azat, Kubodera, Takayuki, Hirai, Takashi, Sunaga, Fumiko, Tajiri, Mio, Hirai, Yukihiko, Shimada, Takashi, Mizusawa, Hidehiro, Yokota, Takanori
Published in Molecular pain (18.07.2013)
Published in Molecular pain (18.07.2013)
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Treatment of hypophosphatasia by muscle-directed expression of bone-targeted alkaline phosphatase via self-complementary AAV8 vector
Nakamura-Takahashi, Aki, Miyake, Koichi, Watanabe, Atsushi, Hirai, Yukihiko, Iijima, Osamu, Miyake, Noriko, Adachi, Kumi, Nitahara-Kasahara, Yuko, Kinoshita, Hideaki, Noguchi, Taku, Abe, Shinichi, Narisawa, Sonoko, Millán, Jose Luis, Shimada, Takashi, Okada, Takashi
Published in Molecular therapy. Methods & clinical development (01.01.2016)
Published in Molecular therapy. Methods & clinical development (01.01.2016)
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In vivo application of an RNAi strategy for the selective suppression of a mutant allele
Kubodera, Takayuki, Yamada, Hiromi, Anzai, Masayuki, Ohira, Shinga, Yokota, Shigefumi, Hirai, Yukihiko, Mochizuki, Hideki, Shimada, Takashi, Mitani, Tasuku, Mizusawa, Hidehiro, Yokota, Takanori
Published in Human gene therapy (01.01.2011)
Published in Human gene therapy (01.01.2011)
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Long-Term Systemic Therapy of Fabry Disease in a Knockout Mouse by Adeno-Associated Virus-Mediated Muscle-Directed Gene Transfer
Takahashi, Hiroshi, Hirai, Yukihiko, Migita, Makoto, Seino, Yoshihiko, Fukuda, Yuh, Sakuraba, Hitoshi, Kase, Ryoichi, Kobayashi, Toshihide, Hashimoto, Yasuhiro, Shimada, Takashi
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2002)
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