De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy
Saitsu, Hirotomo, Matsumoto, Naomichi, Kato, Mitsuhiro, Mizuguchi, Takeshi, Hamada, Keisuke, Osaka, Hitoshi, Tohyama, Jun, Uruno, Katsuhisa, Kumada, Satoko, Nishiyama, Kiyomi, Nishimura, Akira, Okada, Ippei, Yoshimura, Yukiko, Hirai, Syu-ichi, Kumada, Tatsuro, Hayasaka, Kiyoshi, Fukuda, Atsuo, Ogata, Kazuhiro
Published in Nature genetics (01.06.2008)
Published in Nature genetics (01.06.2008)
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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development
Tenenbaum, Mathie, Plaisance, Valérie, Boutry, Raphael, Pawlowski, Valérie, Jacovetti, Cécile, Sanchez-Parra, Clara, Ezanno, Hélène, Bourry, Julien, Beeler, Nicole, Pasquetti, Gianni, Gmyr, Valery, Dalle, Stéphane, Kerr-Conte, Julie, Pattou, François, Hirai, Syu-ichi, Regazzi, Romano, Bonnefond, Amélie, Froguel, Philippe, Abderrahmani, Amar
Published in Cellular and molecular life sciences : CMLS (01.01.2021)
Published in Cellular and molecular life sciences : CMLS (01.01.2021)
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Sensory nerve supports epithelial stem cell function in healing of corneal epithelium in mice: the role of trigeminal nerve transient receptor potential vanilloid 4
Okada, Yuka, Sumioka, Takayoshi, Ichikawa, Kana, Sano, Hiromi, Nambu, Atsushi, Kobayashi, Kenta, Uchida, Kunitoshi, Suzuki, Yoshiro, Tominaga, Makoto, Reinach, Peter Sol, Hirai, Syu-ichi, Jester, James V., Miyajima, Masayasu, Shirai, Kumi, Iwanishi, Hiroki, Kao, Winston Whei-Yang, Liu, Chia-Yang, Saika, Shizuya
Published in Laboratory investigation (01.02.2019)
Published in Laboratory investigation (01.02.2019)
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Axon formation in neocortical neurons depends on stage-specific regulation of microtubule stability by the dual leucine zipper kinase-c-Jun N-terminal kinase pathway
Hirai, Syu-ichi, Banba, Yumi, Satake, Tomoko, Ohno, Shigeo
Published in The Journal of neuroscience (27.04.2011)
Published in The Journal of neuroscience (27.04.2011)
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A Role for DLK in Microtubule Reorganization to the Cell Periphery and in the Maintenance of Desmosomal and Tight Junction Integrity
Simard-Bisson, Carolyne, Bidoggia, Julie, Larouche, Danielle, Guérin, Sylvain L., Blouin, Richard, Hirai, Syu-Ichi, Germain, Lucie
Published in Journal of investigative dermatology (01.01.2017)
Published in Journal of investigative dermatology (01.01.2017)
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EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling
Chen, Qingfa, Arai, Daiki, Kawakami, Kazuki, Sawada, Takahiro, Jing, Xuefeng, Miyajima, Masayasu, Hirai, Syu-Ichi, Sakaguchi, Kazushige, Furushima, Kenryo
Published in PloS one (15.05.2015)
Published in PloS one (15.05.2015)
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Maintenance of dendritic spine morphology by partitioning-defective 1b through regulation of microtubule growth
Hayashi, Kenji, Suzuki, Atsushi, Hirai, Syu-ichi, Kurihara, Yasuyuki, Hoogenraad, Casper C, Ohno, Shigeo
Published in The Journal of neuroscience (24.08.2011)
Published in The Journal of neuroscience (24.08.2011)
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Journal Article
The c-Jun N-Terminal Kinase Activator Dual Leucine Zipper Kinase Regulates Axon Growth and Neuronal Migration in the Developing Cerebral Cortex
Hirai, Syu-ichi, Feng Cui, De, Miyata, Takaki, Ogawa, Masaharu, Kiyonari, Hiroshi, Suda, Yoko, Aizawa, Shinichi, Banba, Yumi, Ohno, Shigeo
Published in The Journal of neuroscience (15.11.2006)
Published in The Journal of neuroscience (15.11.2006)
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Journal Article
The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C
Okuda, Heiwa, Saitoh, Kojiro, Hirai, Syu-ichi, Iwai, Kazuhiro, Takaki, Yasuyuki, Baba, Masaya, Minato, Nagahiro, Ohno, Shigeo, Shuin, Taro
Published in The Journal of biological chemistry (23.11.2001)
Published in The Journal of biological chemistry (23.11.2001)
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Association of ASIP/mPAR‐3 with adherens junctions of mouse neuroepithelial cells
Manabe, Naoyuki, Hirai, Syu‐Ichi, Imai, Fumiyasu, Nakanishi, Hiroyuki, Takai, Yoshimi, Ohno, Shigeo
Published in Developmental dynamics (01.09.2002)
Published in Developmental dynamics (01.09.2002)
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Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death
Welsbie, Derek S., Yang, Zhiyong, Ge, Yan, Mitchell, Katherine L., Zhou, Xinrong, Martin, Scott E., Berlinicke, Cynthia A., Hackler, Laszlo, Fuller, John, Fu, Jie, Cao, Li-hui, Han, Bing, Auld, Douglas, Xue, Tian, Hirai, Syu-ichi, Germain, Lucie, Simard-Bisson, Caroline, Blouin, Richard, Nguyen, Judy V., Davis, Chung-ha O., Enke, Raymond A., Boye, Sanford L., Merbs, Shannath L., Marsh-Armstrong, Nicholas, Hauswirth, William W., DiAntonio, Aaron, Nickells, Robert W., Inglese, James, Hanes, Justin, Yau, King-Wai, Quigley, Harry A., Zack, Donald J.
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2013)
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Dominant-Negative Mutations in α-II Spectrin Cause West Syndrome with Severe Cerebral Hypomyelination, Spastic Quadriplegia, and Developmental Delay
Saitsu, Hirotomo, Tohyama, Jun, Kumada, Tatsuro, Egawa, Kiyoshi, Hamada, Keisuke, Okada, Ippei, Mizuguchi, Takeshi, Osaka, Hitoshi, Miyata, Rie, Furukawa, Tomonori, Haginoya, Kazuhiro, Hoshino, Hideki, Goto, Tomohide, Hachiya, Yasuo, Yamagata, Takanori, Saitoh, Shinji, Nagai, Toshiro, Nishiyama, Kiyomi, Nishimura, Akira, Miyake, Noriko, Komada, Masayuki, Hayashi, Kenji, Hirai, Syu-ichi, Ogata, Kazuhiro, Kato, Mitsuhiro, Fukuda, Atsuo, Matsumoto, Naomichi
Published in American journal of human genetics (11.06.2010)
Published in American journal of human genetics (11.06.2010)
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Journal Article
MST/MLK2, a Member of the Mixed Lineage Kinase Family, Directly Phosphorylates and Activates SEK1, an Activator of c-Jun N-terminal Kinase/Stress-activated Protein Kinase
Hirai, Syu-ichi, Katoh, Masaru, Terada, Masaaki, Kyriakis, John M., Zon, Leonard I., Rana, Ajay, Avruch, Joseph, Ohno, Shigeo
Published in The Journal of biological chemistry (13.06.1997)
Published in The Journal of biological chemistry (13.06.1997)
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Journal Article
Inactivation of aPKCλ results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex
Imai, Fumiyasu, Hirai, Syu-ichi, Akimoto, Kazunori, Koyama, Hiromichi, Miyata, Takaki, Ogawa, Masaharu, Noguchi, Shigeru, Sasaoka, Toshikuni, Noda, Tetsuo, Ohno, Shigeo
Published in Development (Cambridge) (01.05.2006)
Published in Development (Cambridge) (01.05.2006)
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Journal Article
Tumor suppressor protein VHL is induced at high cell density and mediates contact inhibition of cell growth
BABA, Masaya, HIRAI, Syu-Ichi, OHNO, Shigeo, KAWAKAMI, Satoshi, KISHIDA, Takeshi, SAKAI, Naoki, KANEKO, Shigeki, YAO, Masahiro, SHUIN, Taro, KUBOTA, Yoshinobu, HOSAKA, Masahiko
Published in Oncogene (17.05.2001)
Published in Oncogene (17.05.2001)
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Journal Article
MAPK Upstream Kinase (MUK)-binding Inhibitory Protein, a Negative Regulator of MUK/Dual Leucine Zipper-bearing Kinase/Leucine Zipper Protein Kinase
Fukuyama, Keiko, Yoshida, Michihiko, Yamashita, Akio, Deyama, Tetsuya, Baba, Masaya, Suzuki, Atsushi, Mohri, Hiroshi, Ikezawa, Zenro, Nakajima, Hiroshi, Hirai, Syu-ichi, Ohno, Shigeo
Published in The Journal of biological chemistry (14.07.2000)
Published in The Journal of biological chemistry (14.07.2000)
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Journal Article
Dynamic changes in protein components of the tight junction during liver regeneration
Takaki, Y, Hirai, S, Manabe, N, Izumi, Y, Hirose, T, Nakaya, M, Suzuki, A, Mizuno, K, Akimoto, K, Tsukita, S, Shuin, T, Ohno, S
Published in Cell and tissue research (01.09.2001)
Published in Cell and tissue research (01.09.2001)
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