Structure-Based Design of Novel HIV Protease Inhibitors: Sulfonamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non-Peptidic Inhibitors
Thaisrivongs, Suvit, Janakiraman, Musiri N, Chong, Kong-Teck, Tomich, Paul K, Dolak, Lester A, Turner, Steve R, Strohbach, Joseph W, Lynn, Janet C, Horng, Miao-Miao, Hinshaw, Roger R, Watenpaugh, Keith D
Published in Journal of medicinal chemistry (07.06.1996)
Published in Journal of medicinal chemistry (07.06.1996)
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Journal Article
Structure-Based Design of HIV Protease Inhibitors: 5,6-Dihydro-4-hydroxy-2-pyrones as Effective, Nonpeptidic Inhibitors
Thaisrivongs, Suvit, Romero, Donna L, Tommasi, Ruben A, Janakiraman, Musiri N, Strohbach, Joseph W, Turner, Steve R, Biles, Carolyn, Morge, Raymond R, Johnson, Paul D, Aristoff, Paul A, Tomich, Paul K, Lynn, Janet C, Horng, Miao-Miao, Chong, Kong-Teck, Hinshaw, Roger R, Howe, W. Jeffrey, Finzel, Barry C, Watenpaugh, Keith D
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
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Journal Article
Cycloalkylpyranones and Cycloalkyldihydropyrones as HIV Protease Inhibitors: Exploring the Impact of Ring Size on Structure−Activity Relationships
Romines, Karen R, Morris, Jeanette K, Howe, W. Jeffrey, Tomich, Paul K, Horng, Miao-Miao, Chong, Kong-Teck, Hinshaw, Roger R, Anderson, David J, Strohbach, Joseph W, Turner, Steve R, Mizsak, Steve A
Published in Journal of medicinal chemistry (27.09.1996)
Published in Journal of medicinal chemistry (27.09.1996)
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Journal Article
Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities
Chong, Kong Teck, Ruwart, Mary J, Hinshaw, Roger R, Wilkinson, Karen F, Rush, Bob D, Yancey, Mark F, Strohbach, Joseph W, Thaisrivongs, Suvit
Published in Journal of medicinal chemistry (20.08.1993)
Published in Journal of medicinal chemistry (20.08.1993)
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Journal Article
Tipranavir (PNU-140690): A Potent, Orally Bioavailable Nonpeptidic HIV Protease Inhibitor of the 5,6-Dihydro-4-hydroxy-2-pyrone Sulfonamide Class
Turner, Steve R, Strohbach, Joseph W, Tommasi, Ruben A, Aristoff, Paul A, Johnson, Paul D, Skulnick, Harvey I, Dolak, Lester A, Seest, Eric P, Tomich, Paul K, Bohanon, Michael J, Horng, Miao-Miao, Lynn, Janet C, Chong, Kong-Teck, Hinshaw, Roger R, Watenpaugh, Keith D, Janakiraman, Musiri N, Thaisrivongs, Suvit
Published in Journal of medicinal chemistry (27.08.1998)
Published in Journal of medicinal chemistry (27.08.1998)
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Journal Article
Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors
Thaisrivongs, Suvit, Tomich, Paul K, Watenpaugh, Keith D, Chong, Kong-Teck, Howe, W. Jeffrey, Yang, Chih-Ping, Strohbach, Joseph W, Turner, Steve R, McGrath, James P
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Journal Article
Structure-Based Design of Nonpeptidic HIV Protease Inhibitors: The Sulfonamide-Substituted Cyclooctylpyranones
Skulnick, Harvey I, Johnson, Paul D, Aristoff, Paul A, Morris, Jeanette K, Lovasz, Kristine D, Howe, W. Jeffrey, Watenpaugh, Keith D, Janakiraman, Musiri N, Anderson, David J, Reischer, Robert J, Schwartz, Theresa M, Banitt, Lee S, Tomich, Paul K, Lynn, Janet C, Horng, Miao-Miao, Chong, Kong-Teck, Hinshaw, Roger R, Dolak, Lester A, Seest, Eric P, Schwende, Francis J, Rush, Bob D, Howard, Gina M, Toth, Lisa N, Wilkinson, Karen R, Kakuk, Thomas J, Johnson, Carol W, Cole, Serena L, Zaya, Renee M, Zipp, Gail L, Possert, Peggy L, Dalga, Robert J, Zhong, Wei-Zhu, Williams, Marta G, Romines, Karen R
Published in Journal of medicinal chemistry (28.03.1997)
Published in Journal of medicinal chemistry (28.03.1997)
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Journal Article
Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors
Thaisrivongs, Suvit, Watenpaugh, Keith D, Howe, W. Jeffrey, Tomich, Paul K, Dolak, Lester A, Chong, Kong-Teck, Tomich, Che-Shen C, Tomasselli, Alfredo G, Turner, Steve R
Published in Journal of medicinal chemistry (01.09.1995)
Published in Journal of medicinal chemistry (01.09.1995)
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Journal Article
Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors
Romines, Karen R, Watenpaugh, Keith D, Tomich, Paul K, Howe, W. Jeffrey, Morris, Jeanette K, Lovasz, Kristine D, Mulichak, Anne M, Finzel, Barry C, Lynn, Janet C
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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Journal Article
Structure-Based Design of Nonpeptidic HIV Protease Inhibitors from a Cyclooctylpyranone Lead Structure
Romines, Karen R, Watenpaugh, Keith D, Howe, W. Jeffrey, Tomich, Paul K, Lovasz, Kristine D, Morris, Jeanette K, Janakiraman, Musiri N, Lynn, Janet C, Horng, Miao-Miao
Published in Journal of medicinal chemistry (01.10.1995)
Published in Journal of medicinal chemistry (01.10.1995)
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Journal Article
Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors
Schwartz, Theresa M., Bundy, Gordon L., Strohbach, Joseph W., Thaisrivongs, Suvit, Johnson, Paul D., Skulnick, Harvey I., Tomich, Paul K., Lynn, Janet C., Chong, Kong Teck, Hinshaw, Roger R., Raub, Thomas J., Padbury, Guy E., Toth, Lisa N.
Published in Bioorganic & medicinal chemistry letters (18.02.1997)
Published in Bioorganic & medicinal chemistry letters (18.02.1997)
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