Discovery of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor
Harris, Philip A, Boloor, Amogh, Cheung, Mui, Kumar, Rakesh, Crosby, Renae M, Davis-Ward, Ronda G, Epperly, Andrea H, Hinkle, Kevin W, Hunter, Robert N, Johnson, Jennifer H, Knick, Victoria B, Laudeman, Christopher P, Luttrell, Deirdre K, Mook, Robert A, Nolte, Robert T, Rudolph, Sharon K, Szewczyk, Jerzy R, Truesdale, Anne T, Veal, James M, Wang, Liping, Stafford, Jeffrey A
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors
Waterson, Alex G., Petrov, Kimberly G., Hornberger, Keith R., Hubbard, Robert D., Sammond, Douglas M., Smith, Stephon C., Dickson, Hamilton D., Caferro, Thomas R., Hinkle, Kevin W., Stevens, Kirk L., Dickerson, Scott H., Rusnak, David W., Spehar, Glenn M., Wood, Edgar R., Griffin, Robert J., Uehling, David E.
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide (pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor
Harris, Philip A., Boloor, Amogh, Cheung, Mui, Kumar, Rakesh, Crosby, Renae M., Davis-Ward, Ronda G., Epperly, Andrea H., Hinkle, Kevin W., Hunter, Robert N., Johnson, Jennifer H., Knick, Victoria B., Laudeman, Christopher P., Luttrell, Deirdre K., Mook, Robert A., Nolte, Robert T., Rudolph, Sharon K., Szewczyk, Jerzy R., Truesdale, Anne T., Veal, James M., Wang, Liping, Stafford, Jeffrey A.
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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A convenient scalable one-pot conversion of esters and Weinreb amides to terminal alkynes
Dickson, Hamilton D., Smith, Stephon C., Hinkle, Kevin W.
Published in Tetrahedron letters (01.07.2004)
Published in Tetrahedron letters (01.07.2004)
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The rational design of potential chemotherapeutic agents: Synthesis of bryostatin analogues
Wender, Paul A., Hinkle, Kevin W., Koehler, Michael F. T., Lippa, Blaise
Published in Medicinal research reviews (01.09.1999)
Published in Medicinal research reviews (01.09.1999)
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Conference Proceeding
Synthesis and biological evaluation of fully synthetic bryostatin analogues
Wender, Paul A., De Brabander, Jef, Harran, Patrick G., Hinkle, Kevin W., Lippa, Blaise, Pettit, George R.
Published in Tetrahedron letters (19.11.1998)
Published in Tetrahedron letters (19.11.1998)
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