Paclitaxel‐induced microtubule stabilization causes mitotic block and apoptotic‐like cell death in a paclitaxel‐sensitive strain of Saccharomyces cerevisiae
Foland, Travis B., Dentler, William L., Suprenant, Kathy A., Gupta, Mohan L., Himes, Richard H.
Published in Yeast (Chichester, England) (01.09.2005)
Published in Yeast (Chichester, England) (01.09.2005)
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Suppression of Microtubule Dynamic Instability and Treadmilling by Deuterium Oxide
Panda, Dulal, Chakrabarti, Gopal, Hudson, Jon, Pigg, Karli, Miller, Herbert P, Wilson, Leslie, Himes, Richard H
Published in Biochemistry (Easton) (02.05.2000)
Published in Biochemistry (Easton) (02.05.2000)
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Intrinsically Slow Dynamic Instability of HeLa Cell Microtubules in Vitro
Newton, Cori N, DeLuca, Jennifer G, Himes, Richard H, Miller, Herbert P, Jordan, Mary Ann, Wilson, Leslie
Published in The Journal of biological chemistry (08.11.2002)
Published in The Journal of biological chemistry (08.11.2002)
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Stabilization of Tubulin by Deuterium Oxide
Chakrabarti, Gopal, Kim, Shane, Gupta, Mohan L, Barton, Janice S, Himes, Richard H
Published in Biochemistry (Easton) (09.03.1999)
Published in Biochemistry (Easton) (09.03.1999)
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Chemical Modification of Paclitaxel (Taxol) Reduces P-Glycoprotein Interactions and Increases Permeation across the Blood−Brain Barrier in Vitro and in Situ
Rice, Antonie, Liu, Yanbin, Michaelis, Mary Lou, Himes, Richard H, Georg, Gunda I, Audus, Kenneth L
Published in Journal of medicinal chemistry (10.02.2005)
Published in Journal of medicinal chemistry (10.02.2005)
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A label-free mass spectrometry method for the quantification of protein isotypes
Winefield, Robert D., Williams, Todd D., Himes, Richard H.
Published in Analytical biochemistry (15.12.2009)
Published in Analytical biochemistry (15.12.2009)
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Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood–brain barrier permeability
Turunen, Brandon J., Ge, Haibo, Oyetunji, Jariat, Desino, Kelly E., Vasandani, Veena, Güthe, Sarah, Himes, Richard H., Audus, Kenneth L., Seelig, Anna, Georg, Gunda I.
Published in Bioorganic & medicinal chemistry (15.11.2008)
Published in Bioorganic & medicinal chemistry (15.11.2008)
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Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues
Ahn, Yu Mi, Vogeti, Lakshminarayana, Liu, Chun-Jing, Santhapuram, Hari K.R., White, Jonathan M., Vasandani, Veena, Mitscher, Lester A., Lushington, Gerald H., Hanson, Paul R., Powell, Douglas R., Himes, Richard H., Roby, Katherine F., Ye, Qizhuang, Georg, Gunda I.
Published in Bioorganic & medicinal chemistry (15.01.2007)
Published in Bioorganic & medicinal chemistry (15.01.2007)
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Differentiating between Models of Epothilone Binding to Microtubules Using Tubulin Mutagenesis, Cytotoxicity, and Molecular Modeling
Entwistle, Ruth A., Rizk, Rania S., Cheng, Daniel M., Lushington, Gerald H., Himes, Richard H., Gupta Jr, Mohan L.
Published in ChemMedChem (01.09.2012)
Published in ChemMedChem (01.09.2012)
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Total Synthesis and Evaluation of C26-Hydroxyepothilone D Derivatives for Photoaffinity Labeling of β-Tubulin
Reiff, Emily A, Nair, Sajiv K, Henri, John T, Greiner, Jack F, Reddy, Bollu S, Chakrasali, Ramappa, David, Sunil A, Chiu, Ting-Lan, Amin, Elizabeth A, Himes, Richard H, Vander Velde, David G, Georg, Gunda I
Published in Journal of organic chemistry (01.01.2010)
Published in Journal of organic chemistry (01.01.2010)
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(3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a Novel Neuroprotective Agent
Desino, Kelly E, Ansar, Sabah, Georg, Gunda I, Himes, Richard H, Michaelis, Mary Lou, Powell, Douglas R, Reiff, Emily A, Telikepalli, Hanumaiah, Audus, Kenneth L
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Enantiospecific synthesis and cytotoxicity of 7-(4-methoxyphenyl)-6-phenyl-2,3,8,8a-tetrahydroindolizin-5(1 H)-one enantiomers
Kimball, F. Scott, Turunen, Brandon J., Ellis, Keith C., Himes, Richard H., Georg, Gunda I.
Published in Bioorganic & medicinal chemistry (15.04.2008)
Published in Bioorganic & medicinal chemistry (15.04.2008)
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Synthesis, in vitro and in vivo cytotoxicity of 6,7-diaryl-2,3,8,8a-tetrahydroindolizin-5(1H)-ones
Kimball, F. Scott, Tunoori, Ashok Rao, Victory, Samuel F., Dutta, Dinah, White, Jonathan M., Himes, Richard H., Georg, Gunda I.
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
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Synthesis, tubulin assembly, and antiproliferative activity against MCF7 and NCI/ADR-RES cancer cells of 10-O-acetyl-5'-hydroxybutitaxel
HAIBO GE, JIANMEI WANG, KAYSER, Margaret M, HIMES, Richard H, GEORG, Gunda I
Published in Bioorganic & medicinal chemistry (01.12.2008)
Published in Bioorganic & medicinal chemistry (01.12.2008)
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The two α-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro
Bode, Claudia J, Gupta Jr, Mohan L, Suprenant, Kathy A, Himes, Richard H
Published in EMBO reports (01.01.2003)
Published in EMBO reports (01.01.2003)
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