Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody
Valenzuela Nieto, Guillermo, Jara, Ronald, Watterson, Daniel, Modhiran, Naphak, Amarilla, Alberto A., Himelreichs, Johanna, Khromykh, Alexander A., Salinas-Rebolledo, Constanza, Pinto, Teresa, Cheuquemilla, Yorka, Margolles, Yago, López González del Rey, Natalia, Miranda-Chacon, Zaray, Cuevas, Alexei, Berking, Anne, Deride, Camila, González-Moraga, Sebastián, Mancilla, Héctor, Maturana, Daniel, Langer, Andreas, Toledo, Juan Pablo, Müller, Ananda, Uberti, Benjamín, Krall, Paola, Ehrenfeld, Pamela, Blesa, Javier, Chana-Cuevas, Pedro, Rehren, German, Schwefel, David, Fernandez, Luis Ángel, Rojas-Fernandez, Alejandro
Published in Scientific reports (08.02.2021)
Published in Scientific reports (08.02.2021)
Get full text
Journal Article
A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants
Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D.J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian, Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L., Young, Paul R., Chappell, Keith, Bailey, Dalan, Kjaer, Andreas, Herth, Matthias Manfred, Jurado, Kellie Ann, Schwefel, David, Rojas-Fernandez, Alejandro, Watterson, Daniel
Published in iScience (21.07.2023)
Published in iScience (21.07.2023)
Get full text
Journal Article
Assessing Convalescent Plasma Efficacy in Moderate COVID-19 Hospitalizations: A Bicentric Retrospective Study
Torres, Vivianne, Olivares, Felipe, Fernández, Catherine, Calvo, Mario, Orellana, Claudio, Navarrete, Maritza, Lesina, Blaz, Fuentes, Mónica, Blackburn, Eileen, Velásquez, Gerardo, Vera, Alejandra, Rojas-Fernández, Alejandro, Himelreichs, Johanna
Published in Revista medíca de Chile (01.06.2023)
Published in Revista medíca de Chile (01.06.2023)
Get full text
Journal Article
나노항체 생성을 위한 신속 단일-단계 구배 방법 (RAPID SINGLE-STEP GRADIENT METHOD FOR THE GENERATION OF NANOANTIBODIES)
ROJAS ALEJANDRO, JARA RONALD, SALINAS CONSTANZA, UBERTI BENJAMIN, VALENZUELA GUILLERMO, MULLER ANANDA, PINTO TERESA, LOPEZ NATALIA, CUEVAS ALEXEI, MIRANDA ZARAY, HIMELREICHS JOHANNA, CHEUQUEMILLA YORKA
Year of Publication 12.05.2023
Get full text
Year of Publication 12.05.2023
Patent
Uso de plasma de convalecientes de COVID-19 en pacientes hospitalizados por SARS-CoV-2 de moderada grave-dad en la Región de Los Ríos, Chile
Torres, Vivianne, Olivares, Felipe, Fernández, Catherine, Calvo, Mario, Orellana, Claudio, Navarrete, Maritza, Lesina, Blaz, Fuentes, Mónica, Blackburn, Eileen, Velásquez, Gerardo, Vera, Alejandra, Rojas-Fernández, Alejandro, Himelreichs, Johanna
Published in Revista medíca de Chile (01.06.2023)
Published in Revista medíca de Chile (01.06.2023)
Get full text
Journal Article
RAPID SINGLE-STEP GRADIENT METHOD FOR THE GENERATION OF NANOANTIBODIES
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 07.08.2024
Get full text
Year of Publication 07.08.2024
Patent
SINGLE DOMAIN VHH ANTIBODIES AGAINST SARS-COV-2 VIRUS
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 24.07.2024
Get full text
Year of Publication 24.07.2024
Patent
SINGLE DOMAIN VHH ANTIBODIES AGAINST SARS-COV-2 VIRUS
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 29.02.2024
Get full text
Year of Publication 29.02.2024
Patent
Novel Library Assembly Technique for Developing Nanobodies Targeting IPNv VP2 Protein
Pino-Belmar, Camila, Himelreichs, Johanna, Deride, Camila, Matute, Tamara, Nunez, Isaac, Cazaux, Severine, Federici, Fernan, Moreno, Karen, Genaro Soto Rauch, Munizaga, Jose, Haussmann, Denise, Rojas-Fernandez, Alejandro, Figueroa, Jaime, Valenzuela-Nieto, Guillermo E
Published in bioRxiv (17.11.2024)
Published in bioRxiv (17.11.2024)
Get full text
Paper
ONE-STEP FAST GRADIENT METHOD FOR NANOANTIBODY GENERATION
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 12.10.2023
Get full text
Year of Publication 12.10.2023
Patent
Anticuerpos de dominio simple vhh contra el virus sars-cov-2
Teresa Pinto, Alexei Cuevas, Ananda Muller, Alejandro Rojas, Constanza Salinas, Natalia López, Benjamín Uberti, Ronald Jara, Zaray Miranda, Guillermo Valenzuela, Johanna Himelreichs, Yorka Cheuquemilla
Year of Publication 07.07.2023
Get full text
Year of Publication 07.07.2023
Patent
RAPID SINGLE-STEP GRADIENT METHOD FOR THE GENERATION OF NANOANTIBODIES
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 22.03.2023
Get full text
Year of Publication 22.03.2023
Patent
SINGLE DOMAIN VHH ANTIBODIES AGAINST SARS-COV-2 VIRUS
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 22.03.2023
Get full text
Year of Publication 22.03.2023
Patent
SINGLE DOMAIN VHH ANTIBODIES AGAINST SARS-COV-2 VIRUS
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 23.12.2021
Get full text
Year of Publication 23.12.2021
Patent
ONE-STEP FAST GRADIENT METHOD FOR NANOANTIBODY GENERATION
ROJAS, ALEJANDRO, LOPEZ, NATALIA, HIMELREICHS, JOHANNA, SALINAS, CONSTANZA, CHEUQUEMILLA, YORKA, CUEVAS, ALEXEI, UBERTI, BENJAMIN, VALENZUELA, GUILLERMO, MULLER, ANANDA, PINTO, TERESA, MIRANDA, ZARAY, JARA, RONALD
Year of Publication 18.11.2021
Get full text
Year of Publication 18.11.2021
Patent
SINGLE DOMAIN VHH ANTIBODIES AGAINST SARS-COV-2 VIRUS
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 18.11.2021
Get full text
Year of Publication 18.11.2021
Patent
RAPID SINGLE-STEP GRADIENT METHOD FOR THE GENERATION OF NANOANTIBODIES
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 18.11.2021
Get full text
Year of Publication 18.11.2021
Patent
VHH SINGLE-DOMAIN ANTIBODIES AGAINST SARS-COV-2 VIRUS
LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
Year of Publication 18.11.2021
Get full text
Year of Publication 18.11.2021
Patent
An alpaca-derived nanobody neutralizes the SARS-CoV-2 omicron variant
Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A, Hewins, Peter, Sara Irene Lopes Van Den Broek, Yu Shang Low, Thakur, Nazia, Liang, Benjamin, Guillermo Valenzuela Nieto, Jung, James, Paramitha, Devina, Isaacs, Ariel, De Sng, Julian, Song, David, Jorgensen, Jesper, Yorka Cheuquemilla, Burger, Jorg, Ida Vang Andersen, Himelreichs, Johanna, Jara, Ronald, Macloughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Christian Mt Spahn, Mielke, Thorsten, Khromykh, Alexander A, Munro, Trent, Jones, Martina, Young, Paul R, Chappell, Keith, Bailey, Dalan, Kjaer, Andreas, Herth, Matthias Manfred, Jurado, Kellie Ann, Schwefel, David, Rojas-Fernandez, Alejandro, Watterson, Daniel
Published in bioRxiv (27.12.2022)
Published in bioRxiv (27.12.2022)
Get full text
Paper
Método de gradiente rápido de un solo paso para la generación de nanoanticuerpos
Teresa Pinto, Alexei Cuevas, Ananda Muller, Alejandro Rojas, Constanza Salinas, Natalia López, Benjamín Uberti, Ronald Jara, Zaray Miranda, Guillermo Valenzuela, Johanna Himelreichs, Yorka Cheuquemilla
Year of Publication 24.03.2023
Get full text
Year of Publication 24.03.2023
Patent