Co-evolution of MHC class I and variable NK cell receptors in placental mammals
Guethlein, Lisbeth A., Norman, Paul J., Hilton, Hugo G., Parham, Peter
Published in Immunological reviews (01.09.2015)
Published in Immunological reviews (01.09.2015)
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Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity
Hilton, Hugo G, Rubinstein, Nimrod D, Janki, Peter, Ireland, Andrea T, Bernstein, Nicholas, Fong, Nicole L, Wright, Kevin M, Smith, Megan, Finkle, David, Martin-McNulty, Baby, Roy, Margaret, Imai, Denise M, Jojic, Vladimir, Buffenstein, Rochelle
Published in PLoS biology (21.11.2019)
Published in PLoS biology (21.11.2019)
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Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans
Norman, Paul J, Hollenbach, Jill A, Nemat-Gorgani, Neda, Guethlein, Lisbeth A, Hilton, Hugo G, Pando, Marcelo J, Koram, Kwadwo A, Riley, Eleanor M, Abi-Rached, Laurent, Parham, Peter
Published in PLoS genetics (01.10.2013)
Published in PLoS genetics (01.10.2013)
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Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population
Hilton, Hugo G, Norman, Paul J, Nemat-Gorgani, Neda, Goyos, Ana, Hollenbach, Jill A, Henn, Brenna M, Gignoux, Christopher R, Guethlein, Lisbeth A, Parham, Peter
Published in PLoS genetics (01.08.2015)
Published in PLoS genetics (01.08.2015)
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Journal Article
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome
Illing, Patricia T., Pymm, Phillip, Croft, Nathan P., Hilton, Hugo G., Jojic, Vladimir, Han, Alex S., Mendoza, Juan L., Mifsud, Nicole A., Dudek, Nadine L., McCluskey, James, Parham, Peter, Rossjohn, Jamie, Vivian, Julian P., Purcell, Anthony W.
Published in Nature communications (08.11.2018)
Published in Nature communications (08.11.2018)
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Journal Article
Class I HLA haplotypes form two schools that educate NK cells in different ways
Horowitz, Amir, Djaoud, Zakia, Nemat-Gorgani, Neda, Blokhuis, Jeroen, Hilton, Hugo G, Béziat, Vivien, Malmberg, Karl-Johan, Norman, Paul J, Guethlein, Lisbeth A, Parham, Peter
Published in Science immunology (01.09.2016)
Published in Science immunology (01.09.2016)
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High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia
Huhn, Oisín, Chazara, Olympe, Ivarsson, Martin A, Retière, Christelle, Venkatesan, Timothy C, Norman, Paul J, Hilton, Hugo G, Jayaraman, Jyothi, Traherne, James A, Trowsdale, John, Ito, Mitsutero, Kling, Christiane, Parham, Peter, Ghadially, Hormas, Moffett, Ashley, Sharkey, Andrew M, Colucci, Francesco
Published in The Journal of immunology (1950) (01.11.2018)
Published in The Journal of immunology (1950) (01.11.2018)
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Genetic diversity affects the nanoscale membrane organization and signaling of natural killer cell receptors
Kennedy, Philippa R, Barthen, Charlotte, Williamson, David J, Pitkeathly, William T E, Hazime, Khodor S, Cumming, Joshua, Stacey, Kevin B, Hilton, Hugo G, Carrington, Mary, Parham, Peter, Davis, Daniel M
Published in Science signaling (17.12.2019)
Published in Science signaling (17.12.2019)
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Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2 + HLA-C in Two Indigenous Human Populations in Southern Africa
Nemat-Gorgani, Neda, Hilton, Hugo G, Henn, Brenna M, Lin, Meng, Gignoux, Christopher R, Myrick, Justin W, Werely, Cedric J, Granka, Julie M, Möller, Marlo, Hoal, Eileen G, Yawata, Makoto, Yawata, Nobuyo, Boelen, Lies, Asquith, Becca, Parham, Peter, Norman, Paul J
Published in The Journal of immunology (1950) (15.04.2018)
Published in The Journal of immunology (1950) (15.04.2018)
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Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3
Hilton, Hugo G, Vago, Luca, Older Aguilar, Anastazia M, Moesta, Achim K, Graef, Thorsten, Abi-Rached, Laurent, Norman, Paul J, Guethlein, Lisbeth A, Fleischhauer, Katharina, Parham, Peter
Published in The Journal of immunology (1950) (01.08.2012)
Published in The Journal of immunology (1950) (01.08.2012)
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The Intergenic Recombinant HLA-B∗46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands
Hilton, Hugo G., McMurtrey, Curtis P., Han, Alex S., Djaoud, Zakia, Guethlein, Lisbeth A., Blokhuis, Jeroen H., Pugh, Jason L., Goyos, Ana, Horowitz, Amir, Buchli, Rico, Jackson, Ken W., Bardet, Wilfred, Bushnell, David A., Robinson, Philip J., Mendoza, Juan L., Birnbaum, Michael E., Nielsen, Morten, Garcia, K. Christopher, Hildebrand, William H., Parham, Peter
Published in Cell reports (Cambridge) (16.05.2017)
Published in Cell reports (Cambridge) (16.05.2017)
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A Distinctive Cytoplasmic Tail Contributes to Low Surface Expression and Intracellular Retention of the Patr-AL MHC Class I Molecule
Goyos, Ana, Guethlein, Lisbeth A, Horowitz, Amir, Hilton, Hugo G, Gleimer, Michael, Brodsky, Frances M, Parham, Peter
Published in The Journal of immunology (1950) (15.10.2015)
Published in The Journal of immunology (1950) (15.10.2015)
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Journal Article
Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes
Guethlein, Lisbeth A, Norman, Paul J, Heijmans, Corinne M C, de Groot, Natasja G, Hilton, Hugo G, Babrzadeh, Farbod, Abi-Rached, Laurent, Bontrop, Ronald E, Parham, Peter
Published in The Journal of immunology (1950) (15.04.2017)
Published in The Journal of immunology (1950) (15.04.2017)
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Correction: High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia
Huhn, Oisín, Chazara, Olympe, Ivarsson, Martin A, Retière, Christelle, Venkatesan, Timothy C, Norman, Paul J, Hilton, Hugo G, Jayaraman, Jyothi, Traherne, James A, Trowsdale, John, Ito, Mitsutero, Kling, Christiane, Parham, Peter, Ghadially, Hormas, Moffett, Ashley, Sharkey, Andrew M, Colucci, Francesco
Published in The Journal of immunology (1950) (15.03.2019)
Published in The Journal of immunology (1950) (15.03.2019)
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KIR2DS5 allotypes that recognize the C2 epitope of HLA‐C are common among Africans and absent from Europeans
Blokhuis, Jeroen H., Hilton, Hugo G., Guethlein, Lisbeth A., Norman, Paul J., Nemat‐Gorgani, Neda, Nakimuli, Annettee, Chazara, Olympe, Moffett, Ashley, Parham, Peter
Published in Immunity, Inflammation and Disease (01.12.2017)
Published in Immunity, Inflammation and Disease (01.12.2017)
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