A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways
Agnew, Thomas, Goldsworthy, Michelle, Aguilar, Carlos, Morgan, Anna, Simon, Michelle, Hilton, Helen, Esapa, Chris, Wu, Yixing, Cater, Heather, Bentley, Liz, Scudamore, Cheryl, Poulton, Joanna, Morten, Karl J., Thompson, Kyle, He, Langping, Brown, Steve D.M., Taylor, Robert W., Bowl, Michael R., Cox, Roger D.
Published in Cell reports (Cambridge) (18.12.2018)
Published in Cell reports (Cambridge) (18.12.2018)
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Scribble is required for normal epithelial cell–cell contacts and lumen morphogenesis in the mammalian lung
Yates, Laura L., Schnatwinkel, Carsten, Hazelwood, Lee, Chessum, Lauren, Paudyal, Anju, Hilton, Helen, Romero, M. Rosario, Wilde, Jonathan, Bogani, Debora, Sanderson, Jeremy, Formstone, Caroline, Murdoch, Jennifer N., Niswander, Lee A., Greenfield, Andy, Dean, Charlotte H.
Published in Developmental biology (15.01.2013)
Published in Developmental biology (15.01.2013)
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ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis
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Published in Development (Cambridge) (01.10.2014)
Published in Development (Cambridge) (01.10.2014)
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Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration
Joyce, Peter I, Fratta, Pietro, Landman, Allison S, Mcgoldrick, Philip, Wackerhage, Henning, Groves, Michael, Busam, Bharani Shiva, Galino, Jorge, Corrochano, Silvia, Beskina, Olga A, Esapa, Christopher, Ryder, Edward, Carter, Sarah, Stewart, Michelle, Codner, Gemma, Hilton, Helen, Teboul, Lydia, Tucker, Jennifer, Lionikas, Arimantas, Estabel, Jeanne, Ramirez-Solis, Ramiro, White, Jacqueline K, Brandner, Sebastian, Plagnol, Vincent, Bennet, David L H, Abramov, Andrey Y, Greensmith, Linda, Fisher, Elizabeth M C, Acevedo-Arozena, Abraham
Published in Human molecular genetics (15.01.2016)
Published in Human molecular genetics (15.01.2016)
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HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants
Cheeseman, Michael T, Tyrer, Hayley E, Williams, Debbie, Hough, Tertius A, Pathak, Paras, Romero, Maria R, Hilton, Helen, Bali, Sulzhan, Parker, Andrew, Vizor, Lucie, Purnell, Tom, Vowell, Kate, Wells, Sara, Bhutta, Mahmood F, Potter, Paul K, Brown, Steve D M
Published in PLoS genetics (01.10.2011)
Published in PLoS genetics (01.10.2011)
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Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia
Mburu, Philomena, Romero, María Rosario, Hilton, Helen, Parker, Andrew, Townsend, Stuart, Kikkawa, Yoshiaki, Brown, Steve D M
Published in PloS one (16.07.2010)
Published in PloS one (16.07.2010)
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A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal
Siggers, Pam, Carré, Gwenn-Aël, Bogani, Debora, Warr, Nick, Wells, Sara, Hilton, Helen, Esapa, Chris, Hajihosseini, Mohammad K, Greenfield, Andy
Published in PloS one (23.06.2014)
Published in PloS one (23.06.2014)
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Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow
Stevens, Jonathan, Ermakov, Alexander, Braganca, Jose, Hilton, Helen, Underhill, Peter, Bhattacharya, Shoumo, Brown, Nigel A, Norris, Dominic P
Published in BMC developmental biology (20.05.2010)
Published in BMC developmental biology (20.05.2010)
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Atmin modulates Pkhd1 expression and may mediate Autosomal Recessive Polycystic Kidney Disease (ARPKD) through altered non-canonical Wnt/Planar Cell Polarity (PCP) signalling
Richards, Taylor, Modarage, Kavindiya, Dean, Charlotte, McCarthy-Boxer, Aidan, Hilton, Helen, Esapa, Chris, Norman, Jill, Wilson, Patricia, Goggolidou, Paraskevi
Published in Biochimica et biophysica acta. Molecular basis of disease (01.02.2019)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.02.2019)
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Mapping the neuroethological signatures of pain, analgesia, and recovery in mice
Bohic, Manon, Pattison, Luke A., Jhumka, Z. Anissa, Rossi, Heather, Thackray, Joshua K., Ricci, Matthew, Mossazghi, Nahom, Foster, William, Ogundare, Simon, Twomey, Colin R., Hilton, Helen, Arnold, Justin, Tischfield, Max A., Yttri, Eric A., St. John Smith, Ewan, Abdus-Saboor, Ishmail, Abraira, Victoria E.
Published in Neuron (Cambridge, Mass.) (20.09.2023)
Published in Neuron (Cambridge, Mass.) (20.09.2023)
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Digging deeper into pain: an ethological behavior assay correlating well-being in mice with human pain experience
Pattison, Luke A, Cloake, Alexander, Chakrabarti, Sampurna, Hilton, Helen, Rickman, Rebecca H, Higham, James P, Meng, Michelle Y, Paine, Luke W, Dannawi, Maya, Qiu, Lanhui, Ritoux, Anne, Bulmer, David C, Callejo, Gerard, Smith, Ewan St John
Published in Pain (Amsterdam) (01.08.2024)
Published in Pain (Amsterdam) (01.08.2024)
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Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2
Field, Sarah, Riley, Kerry-Lyn, Grimes, Daniel T, Hilton, Helen, Simon, Michelle, Powles-Glover, Nicola, Siggers, Pam, Bogani, Debora, Greenfield, Andy, Norris, Dominic P
Published in Development (Cambridge) (15.03.2011)
Published in Development (Cambridge) (15.03.2011)
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A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons
Perez-Sanchez, Jimena, Middleton, Steven J, Pattison, Luke A, Hilton, Helen, Ali Awadelkareem, Mosab, Zuberi, Sana R, Renke, Maria B, Hu, Huimin, Yang, Xun, Clark, Alex J, St John Smith, Ewan, Bennett, David L
Published in Science translational medicine (04.10.2023)
Published in Science translational medicine (04.10.2023)
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Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features
Tucci, Valter, Kleefstra, Tjitske, Hardy, Andrea, Heise, Ines, Maggi, Silvia, Willemsen, Marjolein H, Hilton, Helen, Esapa, Chris, Simon, Michelle, Buenavista, Maria-Teresa, McGuffin, Liam J, Vizor, Lucie, Dodero, Luca, Tsaftaris, Sotirios, Romero, Rosario, Nillesen, Willy N, Vissers, Lisenka E L M, Kempers, Marlies J, Vulto-van Silfhout, Anneke T, Iqbal, Zafar, Orlando, Marta, Maccione, Alessandro, Lassi, Glenda, Farisello, Pasqualina, Contestabile, Andrea, Tinarelli, Federico, Nieus, Thierry, Raimondi, Andrea, Greco, Barbara, Cantatore, Daniela, Gasparini, Laura, Berdondini, Luca, Bifone, Angelo, Gozzi, Alessandro, Wells, Sara, Nolan, Patrick M
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
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Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor α and disuse
Zaman, Gul, Saxon, Leanne K, Sunters, Andrew, Hilton, Helen, Underhill, Peter, Williams, Debbie, Price, Joanna S, Lanyon, Lance E
Published in Bone (New York, N.Y.) (01.03.2010)
Published in Bone (New York, N.Y.) (01.03.2010)
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Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes
Goldsworthy, Michelle, Bai, Ying, Li, Chi-Ming, Ge, Huanying, Lamas, Edwin, Hilton, Helen, Esapa, Christopher T, Baker, Dan, Baron, Will, Juan, Todd, Véniant, Murielle M, Lloyd, David J, Cox, Roger D
Published in Diabetes (New York, N.Y.) (01.05.2016)
Published in Diabetes (New York, N.Y.) (01.05.2016)
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Atmin mediates kidney morphogenesis by modulating Wnt signaling
Goggolidou, Paraskevi, Hadjirin, Nazreen F, Bak, Aggie, Papakrivopoulou, Eugenia, Hilton, Helen, Norris, Dominic P, Dean, Charlotte H
Published in Human molecular genetics (15.10.2014)
Published in Human molecular genetics (15.10.2014)
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A Novel Mouse Fgfr2 Mutant, Hobbyhorse
Siggers, Pam, Carré, Gwenn-Aël, Bogani, Debora, Warr, Nick, Wells, Sara, Hilton, Helen, Esapa, Chris, Hajihosseini, Mohammad K, Greenfield, Andy
Published in PloS one (23.06.2014)
Published in PloS one (23.06.2014)
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Haplo-Insufficiency of the Insulin Receptor in the presence of a splice-site mutation in Ppp2r2a results in a novel di-genic mouse model of type 2 diabetes
Goldsworthy, Michelle, Bai, Ying, Li, Chi-Ming, Ge, Huanying, Lamas, Edwin, Hilton, Helen, Esapa, Christopher T, Baker, Dan, Baron, Will, Juan, Todd, Véniant, Murielle M, Lloyd, David J, Cox, Roger D
Published in Diabetes (New York, N.Y.) (11.02.2016)
Published in Diabetes (New York, N.Y.) (11.02.2016)
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Identification of a Z-band associated protein complex involving KY, FLNC and IGFN1
Baker, Jane, Riley, Genna, Romero, M. Rosario, Haynes, Andrew R., Hilton, Helen, Simon, Michelle, Hancock, John, Tateossian, Hilda, Ripoll, Vera M., Blanco, Gonzalo
Published in Experimental cell research (01.07.2010)
Published in Experimental cell research (01.07.2010)
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