The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells
Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D’Arcy, Padraig
Published in Scientific reports (06.06.2016)
Published in Scientific reports (06.06.2016)
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Proteasome inhibitor b-AP15 induces enhanced proteotoxicity by inhibiting cytoprotective aggresome formation
Hillert, Ellin-Kristina, Brnjic, Slavica, Zhang, Xiaonan, Mazurkiewicz, Magdalena, Saei, Amir Ata, Mofers, Arjan, Selvaraju, Karthik, Zubarev, Roman, Linder, Stig, D'Arcy, Padraig
Published in Cancer letters (28.04.2019)
Published in Cancer letters (28.04.2019)
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The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and mitochondrial damage
Zhang, Xiaonan, Pellegrini, Paola, Saei, Amir Ata, Hillert, Ellin-Kristina, Mazurkiewicz, Magdalena, Olofsson, Maria Hägg, Zubarev, Roman A., D'Arcy, Pádraig, Linder, Stig
Published in Biochemical pharmacology (01.10.2018)
Published in Biochemical pharmacology (01.10.2018)
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Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)
Min, Xiaoshan, Ungureanu, Daniela, Maxwell, Sarah, Hammarén, Henrik, Thibault, Steve, Hillert, Ellin-Kristina, Ayres, Merrill, Greenfield, Brad, Eksterowicz, John, Gabel, Chris, Walker, Nigel, Silvennoinen, Olli, Wang, Zhulun
Published in The Journal of biological chemistry (06.11.2015)
Published in The Journal of biological chemistry (06.11.2015)
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Journal Article
Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition
Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Wang, Xin, Pellegrini, Paola, Olofsson, Maria Hägg, Selvaraju, Karthik, D’Arcy, Padraig, Linder, Stig
Published in Oncotarget (2017)
Published in Oncotarget (2017)
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The role and therapeutic targeting of α-, β- and γ-secretase in Alzheimer's disease
MacLeod, Ruth, Hillert, Ellin-Kristina, Cameron, Ryan T, Baillie, George S
Published in Future science OA (01.11.2015)
Published in Future science OA (01.11.2015)
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Journal Article
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
Selvaraju, Karthik, Mofers, Arjan, Pellegrini, Paola, Salomonsson, Johannes, Ahlner, Alexandra, Morad, Vivian, Hillert, Ellin-Kristina, Espinosa, Belen, Arnér, Elias S. J., Jensen, Lasse, Malmström, Jonas, Turkina, Maria V., D’Arcy, Padraig, Walters, Michael A., Sunnerhagen, Maria, Linder, Stig
Published in Scientific reports (08.07.2019)
Published in Scientific reports (08.07.2019)
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Abstract 1859: Inhibition of proteasome deubiquitinase activity prevents cytoprotective aggresome formation in cancer cells
Hillert, Ellin-Kristina, Brjnic, Slavica, Mazurkiewicz, Magdalena, Larsson, Rolf, Fryknäs, Mårten, Swanton, Lisa, High, Stephen, Linder, Stig, D'Arcy, Padraig B.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
The deubiquitinase inhibitor b-AP15 induces strong proteotoxic stress and Check for mitochondrial damage
Zhang, Xiaonan, Pellegrini, Paola, Saei, Amir Ata, Hillert, Ellin-Kristina, Mazurkiewicz, Magdalena, Olofsson, Maria Hagg, Zubarev, Roman A., D´arcy, Padraig, Linder, Stig
Published in Biochemical pharmacology (2018)
Published in Biochemical pharmacology (2018)
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Journal Article
Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system (vol 9, 9841, 2019)
Selvaraju, K, Mofers, A, Pellegrini, P, Salomonsson, J, Ahlner, A, Morad, V, Hillert, E-K, Espinosa, B, Arner, ESJ, Jensen, L
Published in SCIENTIFIC REPORTS (20.11.2019)
Published in SCIENTIFIC REPORTS (20.11.2019)
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Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibition
Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Wang, Xin, Pellegrini, Paola, Olofsson, Maria Hägg, Selvaraju, Karthik, D'Arcy, Padraig, Linder, Stig
Published in Oncotarget (28.03.2017)
Published in Oncotarget (28.03.2017)
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Journal Article
Author Correction: Cytotoxic unsaturated electrophilic compounds commonly target the ubiquitin proteasome system
Selvaraju, Karthik, Mofers, Arjan, Pellegrini, Paola, Salomonsson, Johannes, Ahlner, Alexandra, Morad, Vivian, Hillert, Ellin-Kristina, Espinosa, Belen, Arnér, Elias S. J., Jensen, Lasse, Malmström, Jonas, Turkina, Maria V., D’Arcy, Padraig, Walters, Michael A., Sunnerhagen, Maria, Linder, Stig
Published in Scientific reports (20.11.2019)
Published in Scientific reports (20.11.2019)
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Correction: Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells
Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D’Arcy, Padraig
Published in Scientific reports (29.07.2016)
Published in Scientific reports (29.07.2016)
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Journal Article
Corrigendum: The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cells
Wang, Xin, Mazurkiewicz, Magdalena, Hillert, Ellin-Kristina, Olofsson, Maria Hägg, Pierrou, Stefan, Hillertz, Per, Gullbo, Joachim, Selvaraju, Karthik, Paulus, Aneel, Akhtar, Sharoon, Bossler, Felicitas, Khan, Asher Chanan, Linder, Stig, D'Arcy, Padraig
Published in Scientific reports (29.07.2016)
Published in Scientific reports (29.07.2016)
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Journal Article