Panoramic view of a superfamily of phosphatases through substrate profiling
Huang, Hua, Pandya, Chetanya, Liu, Chunliang, Al-Obaidi, Nawar F., Wang, Min, Zheng, Li, Keating, Sarah Toews, Aono, Miyuki, Love, James D., Evans, Brandon, Seidel, Ronald D., Hillerich, Brandan S., Garforth, Scott J., Almo, Steven C., Mariano, Patrick S., Dunaway-Mariano, Debra, Allen, Karen N., Farelli, Jeremiah D.
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
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Discovery of new enzymes and metabolic pathways by using structure and genome context
Zhao, Suwen, Kumar, Ritesh, Sakai, Ayano, Vetting, Matthew W., Wood, B. McKay, Brown, Shoshana, Bonanno, Jeffery B., Hillerich, Brandan S., Seidel, Ronald D., Babbitt, Patricia C., Almo, Steven C., Sweedler, Jonathan V., Gerlt, John A., Cronan, John E., Jacobson, Matthew P.
Published in Nature (London) (31.10.2013)
Published in Nature (London) (31.10.2013)
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Computational-guided discovery and characterization of a sesquiterpene synthase from Streptomyces clavuligerus
Chow, Jeng-Yeong, Tian, Bo-Xue, Ramamoorthy, Gurusankar, Hillerich, Brandan S, Seidel, Ronald D, Almo, Steven C, Jacobson, Matthew P, Poulter, C Dale
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2015)
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Structural genomics for drug design against the pathogen Coxiella burnetii
Franklin, Matthew C., Cheung, Jonah, Rudolph, Michael J., Burshteyn, Fiana, Cassidy, Michael, Gary, Ebony, Hillerich, Brandan, Yao, Zhong-Ke, Carlier, Paul R., Totrov, Maxim, Love, James D.
Published in Proteins, structure, function, and bioinformatics (01.12.2015)
Published in Proteins, structure, function, and bioinformatics (01.12.2015)
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Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks
Zhao, Suwen, Sakai, Ayano, Zhang, Xinshuai, Vetting, Matthew W, Kumar, Ritesh, Hillerich, Brandan, San Francisco, Brian, Solbiati, Jose, Steves, Adam, Brown, Shoshana, Akiva, Eyal, Barber, Alan, Seidel, Ronald D, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P
Published in eLife (30.06.2014)
Published in eLife (30.06.2014)
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Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes
Vetting, Matthew W, Al-Obaidi, Nawar, Zhao, Suwen, San Francisco, Brian, Kim, Jungwook, Wichelecki, Daniel J, Bouvier, Jason T, Solbiati, Jose O, Vu, Hoan, Zhang, Xinshuai, Rodionov, Dmitry A, Love, James D, Hillerich, Brandan S, Seidel, Ronald D, Quinn, Ronald J, Osterman, Andrei L, Cronan, John E, Jacobson, Matthew P, Gerlt, John A, Almo, Steven C
Published in Biochemistry (Easton) (27.01.2015)
Published in Biochemistry (Easton) (27.01.2015)
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Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex
Garrett-Thomson, Sarah C, Massimi, Aldo, Fedorov, Elena V, Bonanno, Jeffrey B, Scandiuzzi, Lisa, Hillerich, Brandan, Seidel, Ronald D, Love, James D, Garforth, Scott J, Guha, Chandan, Almo, Steven C
Published in PloS one (04.06.2020)
Published in PloS one (04.06.2020)
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Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily
Wallrapp, Frank H, Pan, Jian-Jung, Ramamoorthy, Gurusankar, Almonacid, Daniel E, Hillerich, Brandan S, Seidel, Ronald, Patskovsky, Yury, Babbitt, Patricia C, Almo, Steven C, Jacobson, Matthew P, Poulter, C Dale
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2013)
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Homologue structure of the SLAC1 anion channel for closing stomata in leaves
Hendrickson, Wayne A, Chen, Yu-hang, Hu, Lei, Punta, Marco, Bruni, Renato, Hillerich, Brandan, Kloss, Brian, Rost, Burkhard, Love, James, Siegelbaum, Steven A
Published in Nature (London) (28.10.2010)
Published in Nature (London) (28.10.2010)
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Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere
Mashiyama, Susan T, Malabanan, M Merced, Akiva, Eyal, Bhosle, Rahul, Branch, Megan C, Hillerich, Brandan, Jagessar, Kevin, Kim, Jungwook, Patskovsky, Yury, Seidel, Ronald D, Stead, Mark, Toro, Rafael, Vetting, Matthew W, Almo, Steven C, Armstrong, Richard N, Babbitt, Patricia C
Published in PLoS biology (01.04.2014)
Published in PLoS biology (01.04.2014)
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Substrate Distortion and the Catalytic Reaction Mechanism of 5‑Carboxyvanillate Decarboxylase
Vladimirova, Anna, Patskovsky, Yury, Fedorov, Alexander A, Bonanno, Jeffrey B, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald D, Richards, Nigel G. J, Almo, Steven C, Raushel, Frank M
Published in Journal of the American Chemical Society (27.01.2016)
Published in Journal of the American Chemical Society (27.01.2016)
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Advances in Protein Expression: High Throughput Tools for Improving Analysis
Hillerich, Brandan S., Payne, Jason
Published in Science (American Association for the Advancement of Science) (19.04.2013)
Published in Science (American Association for the Advancement of Science) (19.04.2013)
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Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes
Pan, Jian-Jung, Solbiati, Jose O, Ramamoorthy, Gurusankar, Hillerich, Brandan S, Seidel, Ronald D, Cronan, John E, Almo, Steven C, Poulter, C. Dale
Published in ACS central science (27.05.2015)
Published in ACS central science (27.05.2015)
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Discovery of Function in the Enolase Superfamily: d‑Mannonate and d‑Gluconate Dehydratases in the d‑Mannonate Dehydratase Subgroup
Wichelecki, Daniel J, Balthazor, Bryan M, Chau, Anthony C, Vetting, Matthew W, Fedorov, Alexander A, Fedorov, Elena V, Lukk, Tiit, Patskovsky, Yury V, Stead, Mark B, Hillerich, Brandan S, Seidel, Ronald D, Almo, Steven C, Gerlt, John A
Published in Biochemistry (Easton) (29.04.2014)
Published in Biochemistry (Easton) (29.04.2014)
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Discovery of a Novel l‑Lyxonate Degradation Pathway in Pseudomonas aeruginosa PAO1
Ghasempur, Salehe, Eswaramoorthy, Subramaniam, Hillerich, Brandan S, Seidel, Ronald D, Swaminathan, Subramanyam, Almo, Steven C, Gerlt, John A
Published in Biochemistry (Easton) (27.05.2014)
Published in Biochemistry (Easton) (27.05.2014)
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Structural and Mechanistic Characterization of l‑Histidinol Phosphate Phosphatase from the Polymerase and Histidinol Phosphatase Family of Proteins
Ghodge, Swapnil V, Fedorov, Alexander A, Fedorov, Elena V, Hillerich, Brandan, Seidel, Ronald, Almo, Steven C, Raushel, Frank M
Published in Biochemistry (Easton) (12.02.2013)
Published in Biochemistry (Easton) (12.02.2013)
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Journal Article
Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily
Lukk, Tiit, Sakai, Ayano, Kalyanaraman, Chakrapani, Brown, Shoshana D, Imker, Heidi J, Song, Ling, Fedorov, Alexander A, Fedorov, Elena V, Toro, Rafael, Hillerich, Brandan, Seidel, Ronald, Patskovsky, Yury, Vetting, Matthew W, Nair, Satish K, Babbitt, Patricia C, Almo, Steven C, Gerlt, John A, Jacobson, Matthew P
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2012)
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