MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
Coll, Rebecca C., Hill, James R., Day, Christopher J., Zamoshnikova, Alina, Boucher, Dave, Massey, Nicholas L., Chitty, Jessica L., Fraser, James A., Jennings, Michael P., Robertson, Avril A. B., Schroder, Kate
Published in Nature chemical biology (01.06.2019)
Published in Nature chemical biology (01.06.2019)
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The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals
Tucey, Timothy M, Verma-Gaur, Jiyoti, Nguyen, Julie, Hewitt, Victoria L, Lo, Tricia L, Shingu-Vazquez, Miguel, Robertson, Avril A B, Hill, James R, Pettolino, Filomena A, Beddoe, Travis, Cooper, Matthew A, Naderer, Thomas, Traven, Ana
Published in mSphere (01.05.2016)
Published in mSphere (01.05.2016)
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Synthesis and evaluation of NLRP3-inhibitory sulfonylurea [11C]MCC950 in healthy animals
Hill, James R., Shao, Xia, Massey, Nicholas L., Stauff, Jenelle, Sherman, Phillip S., Robertson, Avril A.B., Scott, Peter J.H.
Published in Bioorganic & medicinal chemistry letters (15.06.2020)
Published in Bioorganic & medicinal chemistry letters (15.06.2020)
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Journal Article
Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors
Hill, James R., Coll, Rebecca C., Sue, Nancy, Reid, Janet C., Dou, Jennifer, Holley, Caroline L., Pelingon, Ruby, Dickinson, Joshua B., Biden, Trevor J., Schroder, Kate, Cooper, Matthew A., Robertson, Avril A. B.
Published in ChemMedChem (07.09.2017)
Published in ChemMedChem (07.09.2017)
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Synthesis and Evaluation of 11C- and 18F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents
Hill, James R., Shao, Xia, Wright, Jay S., Stauff, Jenelle, Sherman, Phillip S., Arteaga, Janna, Wong, Ka Kit, Viglianti, Benjamin L., Scott, Peter J. H., Brooks, Allen F.
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
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Journal Article
Synthesis and Evaluation of 11 C- and 18 F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents
Hill, James R, Shao, Xia, Wright, Jay S, Stauff, Jenelle, Sherman, Phillip S, Arteaga, Janna, Wong, Ka Kit, Viglianti, Benjamin L, Scott, Peter J H, Brooks, Allen F
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
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Brood size and late breeding are negatively related to juvenile survival in a Neotropical migratory songbird
Tarof, Scott A, Kramer, Patrick M, Hill, James R, Tautin, John, Stutchbury, Bridget J M
Published in The Auk (01.10.2011)
Published in The Auk (01.10.2011)
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Duration of immunity (DOI) and booster vaccination—dealing with the issue at practice level in the UK
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Conference Proceeding
Design, synthesis and evaluation of an NLRP3 inhibitor diazirine photoaffinity probe
Hill, James R., Coll, Rebecca C., Schroder, Kate, Robertson, Avril A.B.
Published in Tetrahedron letters (07.05.2020)
Published in Tetrahedron letters (07.05.2020)
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Toxicity of a quinocarmycin analog, DX-52-1, in rats and dogs in relation to clinical outcome
MIRSALIS, Jon C, SCHINDLER-HORVAT, Janice, HILL, James R, GREEN, Carol E, MITOMA, Chozo, TOMASZEWSKI, Joseph E, TYSON, Charles A, DONOHUE, Susan J
Published in Cancer chemotherapy and pharmacology (01.03.2003)
Published in Cancer chemotherapy and pharmacology (01.03.2003)
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