Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy
Amoasii, Leonela, Hildyard, John C W, Li, Hui, Sanchez-Ortiz, Efrain, Mireault, Alex, Caballero, Daniel, Harron, Rachel, Stathopoulou, Thaleia-Rengina, Massey, Claire, Shelton, John M, Bassel-Duby, Rhonda, Piercy, Richard J, Olson, Eric N
Published in Science (American Association for the Advancement of Science) (05.10.2018)
Published in Science (American Association for the Advancement of Science) (05.10.2018)
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Journal Article
Multiplex in situ hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics
Hildyard, John C W, Rawson, Faye, Wells, Dominic J, Piercy, Richard J
Published in PloS one (24.09.2020)
Published in PloS one (24.09.2020)
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Journal Article
Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons
Kondori, Nazanin Rahmani, Paul, Praveen, Robbins, Jacqueline P, Liu, Ke, Hildyard, John C W, Wells, Dominic J, de Belleroche, Jacqueline S
Published in PloS one (01.12.2017)
Published in PloS one (01.12.2017)
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Journal Article
Serum inflammatory cytokines as disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy
Riddell, Dominique O, Hildyard, John C W, Harron, Rachel C M, Hornby, Natasha L, Wells, Dominic J, Piercy, Richard J
Published in Disease models & mechanisms (01.12.2022)
Published in Disease models & mechanisms (01.12.2022)
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Journal Article
Longitudinal assessment of skeletal muscle functional mechanics in the DE50-MD dog model of Duchenne muscular dystrophy
Riddell, Dominique O, Hildyard, John C W, Harron, Rachel C M, Taylor-Brown, Frances, Kornegay, Joe N, Wells, Dominic J, Piercy, Richard J
Published in Disease models & mechanisms (01.12.2023)
Published in Disease models & mechanisms (01.12.2023)
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Journal Article
Dystrophin myonuclear domain restoration governs treatment efficacy in dystrophic muscle
Morin, Adrien, Stantzou, Amalia, Petrova, Olga N, Hildyard, John, Tensorer, Thomas, Matouk, Meriem, Petkova, Mina V, Richard, Isabelle, Manoliu, Tudor, Goyenvalle, Aurélie, Falcone, Sestina, Schuelke, Markus, Laplace-Builhé, Corinne, Piercy, Richard J, Garcia, Luis, Amthor, Helge
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2023)
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Journal Article
Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy
Verhaart, Ingrid E.C., Cappellari, Ornella, Tanganyika-de Winter, Christa L., Plomp, Jaap J., Nnorom, Sofia, Wells, Kim E., Hildyard, John C.W., Bull, David, Aartsma-Rus, Annemieke, Wells, Dominic J.
Published in Journal of neuromuscular diseases (01.01.2021)
Published in Journal of neuromuscular diseases (01.01.2021)
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Journal Article
Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)
Kondori, Nazanin R, Paul, Praveen, Robbins, Jacqueline P, Liu, Ke, Hildyard, John C W, Wells, Dominic J, de Belleroche, Jacqueline S
Published in Frontiers in molecular biosciences (13.02.2018)
Published in Frontiers in molecular biosciences (13.02.2018)
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Journal Article
Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo
Hildyard, John C. W., Crawford, Abbe H., Rawson, Faye, Riddell, Dominique O., Harron, Rachel C. M., Piercy, Richard J.
Published in Wellcome open research (2020)
Published in Wellcome open research (2020)
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Journal Article
Identification of quantitative polymerase chain reaction reference genes suitable for normalising gene expression in the brain of normal and dystrophic mice and dogs
Crawford, Abbe H, Hildyard, John C W, Wells, Dominic J, Piercy, Richard J
Published in Wellcome open research (2021)
Published in Wellcome open research (2021)
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Journal Article
Determination of qPCR Reference Genes Suitable for Normalizing Gene Expression in a Canine Model of Duchenne Muscular Dystrophy
Hildyard, John C W, Taylor-Brown, Frances, Massey, Claire, Wells, Dominic J, Piercy, Richard J
Published in Journal of neuromuscular diseases (2018)
Published in Journal of neuromuscular diseases (2018)
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Journal Article
The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy
Hildyard, John C W, Riddell, Dominique O, Harron, Rachel C M, Rawson, Faye, Foster, Emma M A, Massey, Claire, Taylor-Brown, Frances, Wells, Dominic J, Piercy, Richard J
Published in Wellcome open research (2022)
Published in Wellcome open research (2022)
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Journal Article
Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo
Hildyard, John C W, Crawford, Abbe H, Rawson, Faye, Riddell, Dominique O, Harron, Rachel C M, Piercy, Richard J
Published in Wellcome open research (2020)
Published in Wellcome open research (2020)
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Journal Article