Search Results - "Hightower, Kendra E." :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

by HIGHTOWER, Kendra E, WANG, Ruolan, SEKI, Takahiro, KOBAYASHI, Masanori, UNDERWOOD, Mark R, DEANDA, Felix, JOHNS, Brian A, WEAVER, Kurt, YINGNIAN SHEN, TOMBERLIN, Ginger H, LUKE CARTER, H, BRODERICK, Timothy, SIGETHY, Scott
Published in Antimicrobial Agents and Chemotherapy (01.10.2011)

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Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

by DeAnda, Felix, Hightower, Kendra E, Nolte, Robert T, Hattori, Kazunari, Yoshinaga, Tomokazu, Kawasuji, Takashi, Underwood, Mark R
Published in PloS one (16.10.2013)

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N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3

N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3

by Angell, Richard M., Atkinson, Francis L., Brown, Murray J., Chuang, Tsu Tshen, Christopher, John A., Cichy-Knight, Maria, Dunn, Allison K., Hightower, Kendra E., Malkakorpi, Susanna, Musgrave, James R., Neu, Margarete, Rowland, Paul, Shea, Robyn L., Smith, Jeffery L., Somers, Donald O., Thomas, Sonia A., Thompson, Gladstone, Wang, Ruolan
Published in Bioorganic & medicinal chemistry letters (01.03.2007)

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Pyridopyrimidinone inhibitors of HIV-1 RNase H

Pyridopyrimidinone inhibitors of HIV-1 RNase H

by Velthuisen, Emile J., Johns, Brian A., Gerondelis, Peter, Chen, Yan, Li, Ming, Mou, Ke, Zhang, Wenwen, Seal, John W., Hightower, Kendra E., Miranda, Sonia R., Brown, Kevin, Leesnitzer, Lisa
Published in European journal of medicinal chemistry (18.08.2014)

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Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2- c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases

Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2- c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases

by Miyazaki, Yasushi, Nakano, Masato, Sato, Hideyuki, Truesdale, Anne T., Stuart, J. Darren, Nartey, Eldridge N., Hightower, Kendra E., Kane-Carson, Laurie
Published in Bioorganic & medicinal chemistry letters (2007)

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Mechanistic Studies of Rat Protein Farnesyltransferase Indicate an Associative Transition State

Mechanistic Studies of Rat Protein Farnesyltransferase Indicate an Associative Transition State

by Huang, Chih-chin, Hightower, Kendra E, Fierke, Carol A
Published in Biochemistry (Easton) (14.03.2000)

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H-Ras Peptide and Protein Substrates Bind Protein Farnesyltransferase as an Ionized Thiolate

H-Ras Peptide and Protein Substrates Bind Protein Farnesyltransferase as an Ionized Thiolate

by Hightower, Kendra E, Huang, Chih-chin, Casey, Patrick J, Fierke, Carol A
Published in Biochemistry (Easton) (03.11.1998)

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Role of Metals in the Reaction Catalyzed by Protein Farnesyltransferase

Role of Metals in the Reaction Catalyzed by Protein Farnesyltransferase

by Saderholm, Matthew J, Hightower, Kendra E, Fierke, Carol A
Published in Biochemistry (Easton) (10.10.2000)

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Journal Article

Farnesylation of Nonpeptidic Thiol Compounds by Protein Farnesyltransferase

Farnesylation of Nonpeptidic Thiol Compounds by Protein Farnesyltransferase

by Hightower, Kendra E, Casey, Patrick J, Fierke, Carol A
Published in Biochemistry (Easton) (30.01.2001)

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Journal Article

Conversion of Tyr361β to Leu in Mammalian Protein Farnesyltransferase Impairs Product Release but Not Substrate Recognition

Conversion of Tyr361β to Leu in Mammalian Protein Farnesyltransferase Impairs Product Release but Not Substrate Recognition

by Spence, Rebecca A, Hightower, Kendra E, Terry, Kimberly L, Beese, Lorena S, Fierke, Carol A, Casey, Patrick J
Published in Biochemistry (Easton) (14.11.2000)

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Journal Article

Influence of Nucleotides on the Cold Stability of Chloroplast Coupling Factor 1

Influence of Nucleotides on the Cold Stability of Chloroplast Coupling Factor 1

by Hightower, Kendra E, McCarty, Richard E
Published in Biochemistry (Easton) (06.08.1996)

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Zinc-catalyzed sulfur alkylation: insights from protein farnesyltransferase

Zinc-catalyzed sulfur alkylation: insights from protein farnesyltransferase

by Hightower, Kendra E, Fierke, Carol A
Published in Current opinion in chemical biology (01.04.1999)

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Journal Article

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics: e77448

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics: e77448

by DeAnda, Felix, Hightower, Kendra E, Nolte, Robert T, Hattori, Kazunari, Yoshinaga, Tomokazu, Kawasuji, Takashi, Underwood, Mark R
Published in PloS one (01.10.2013)

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The Enzymology of CAAX Protein Prenylation

The Enzymology of CAAX Protein Prenylation

by Hightower, Kendra E., Casey, Patrick J.
Published in Protein Prenylation, Part B (2011)

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Book Chapter

Lysine164α of protein farnesyltransferase is important for both CaaX substrate binding and catalysis

Lysine164α of protein farnesyltransferase is important for both CaaX substrate binding and catalysis

by HIGHTOWER, Kendra E., DE, Smita, WEINBAUM, Carolyn, SPENCE, Rebecca A., CASEY, Patrick J.
Published in Biochemical journal (15.12.2001)

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Journal Article

Lysine164α of protein farnesyltransferase is important for both CaaX substrate binding and catalysis

Lysine164α of protein farnesyltransferase is important for both CaaX substrate binding and catalysis

by HIGHTOWER, Kendra E., DE, Smita, WEINBAUM, Carolyn, SPENCE, Rebecca A., CASEY, Patrick J.
Published in Biochemical journal (15.12.2001)

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Journal Article

Proteolytic Cleavage within a Regulatory Region of the γ Subunit of Chloroplast Coupling Factor 1

Proteolytic Cleavage within a Regulatory Region of the γ Subunit of Chloroplast Coupling Factor 1

by Hightower, Kendra E., McCarty, Richard E.
Published in Biochemistry (Easton) (16.04.1996)

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Journal Article

Structural Stability of Chloroplast Coupling Factor 1 as Determined by Differential Scanning Calorimetry and Cold Inactivation

Structural Stability of Chloroplast Coupling Factor 1 as Determined by Differential Scanning Calorimetry and Cold Inactivation

by Hightower, Kendra E., McCarty, Richard E.
Published in Biochemistry (Easton) (16.04.1996)

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Journal Article

Subunit movement during catalysis by F1-F0-ATP synthases

Subunit movement during catalysis by F1-F0-ATP synthases

by Digel, J G, Hightower, K E, McCarty, R E
Published in Journal of bioenergetics and biomembranes (01.10.1996)

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Design and Effective Synthesis of Novel Templates, 3,7-Diphenyl-4-amino-thieno and Furo-[3,2-c]pyridines as Protein Kinase Inhibitors and in vitro Evaluation Targeting Angiogenetic Kinases

Design and Effective Synthesis of Novel Templates, 3,7-Diphenyl-4-amino-thieno and Furo-[3,2-c]pyridines as Protein Kinase Inhibitors and in vitro Evaluation Targeting Angiogenetic Kinases

by Miyazaki, Yasushi, Nakano, Masato, Sato, Hideyuki, Truesdale, Anne T., Stuart, J. Darren, Nartey, Eldridge N., Hightower, Kendra E., Kane-Carson, Laurie
Published in ChemInform (08.05.2007)

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