Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations
McInnes, Iain B, Byers, Nicole L, Higgs, Richard E, Lee, Jonathan, Macias, William L, Na, Songqing, Ortmann, Robert A, Rocha, Guilherme, Rooney, Terence P, Wehrman, Thomas, Zhang, Xin, Zuckerman, Steven H, Taylor, Peter C
Published in Arthritis research & therapy (02.08.2019)
Published in Arthritis research & therapy (02.08.2019)
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Journal Article
Identification of druggable cancer driver genes amplified across TCGA datasets
Chen, Ying, McGee, Jeremy, Chen, Xianming, Doman, Thompson N, Gong, Xueqian, Zhang, Youyan, Hamm, Nicole, Ma, Xiwen, Higgs, Richard E, Bhagwat, Shripad V, Buchanan, Sean, Peng, Sheng-Bin, Staschke, Kirk A, Yadav, Vipin, Yue, Yong, Kouros-Mehr, Hosein
Published in PloS one (29.05.2014)
Published in PloS one (29.05.2014)
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Journal Article
Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients
Stebbing, Justin, Krishnan, Venkatesh, de Bono, Stephanie, Ottaviani, Silvia, Casalini, Giacomo, Richardson, Peter J, Monteil, Vanessa, Lauschke, Volker M, Mirazimi, Ali, Youhanna, Sonia, Tan, Yee‐Joo, Baldanti, Fausto, Sarasini, Antonella, Terres, Jorge A Ross, Nickoloff, Brian J, Higgs, Richard E, Rocha, Guilherme, Byers, Nicole L, Schlichting, Douglas E, Nirula, Ajay, Cardoso, Anabela, Corbellino, Mario
Published in EMBO molecular medicine (07.08.2020)
Published in EMBO molecular medicine (07.08.2020)
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Journal Article
Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.
Published in Scientific reports (23.07.2014)
Published in Scientific reports (23.07.2014)
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Journal Article
Assessment and Clinical Relevance of Serum IL-19 Levels in Psoriasis and Atopic Dermatitis Using a Sensitive and Specific Novel Immunoassay
Konrad, Robert J., Higgs, Richard E., Rodgers, George H., Ming, Wenyu, Qian, Yue-Wei, Bivi, Nicoletta, Mack, Justin K., Siegel, Robert W., Nickoloff, Brian J.
Published in Scientific reports (26.03.2019)
Published in Scientific reports (26.03.2019)
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Journal Article
Relationship between gene expression patterns from nasopharyngeal swabs and serum biomarkers in patients hospitalized with COVID-19, following treatment with the neutralizing monoclonal antibody bamlanivimab
Sims, Jonathan T, Poorbaugh, Josh, Chang, Ching-Yun, Holzer, Timothy R, Zhang, Lin, Engle, Sarah M, Beasley, Stephanie, Doman, Thompson N, Naughton, Lynn, Higgs, Richard E, Kallewaard, Nicole, Benschop, Robert J
Published in Journal of translational medicine (18.03.2022)
Published in Journal of translational medicine (18.03.2022)
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Journal Article
A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus
Li, Yupeng, Higgs, Richard E, Hoffman, Robert W, Dow, Ernst R, Liu, Xiong, Petri, Michelle, Wallace, Daniel J, Dörner, Thomas, Eastwood, Brian J, Miller, Bradley B, Liu, Yushi
Published in PloS one (02.12.2019)
Published in PloS one (02.12.2019)
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Journal Article
Endogenous Antibody Responses to SARS-CoV-2 in Patients With Mild or Moderate COVID-19 Who Received Bamlanivimab Alone or Bamlanivimab and Etesevimab Together
Zhang, Lin, Poorbaugh, Josh, Dougan, Michael, Chen, Peter, Gottlieb, Robert L, Huhn, Gregory, Beasley, Stephanie, Daniels, Montanea, Ngoc Vy Trinh, Thi, Crisp, Melissa, Freitas, Joshua Joaquin, Vaillancourt, Peter, Patel, Dipak R, Nirula, Ajay, Kallewaard, Nicole L, Higgs, Richard E, Benschop, Robert J
Published in Frontiers in immunology (09.12.2021)
Published in Frontiers in immunology (09.12.2021)
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Journal Article
Sediment provenance in the Murchison and Maruia basins, Aotearoa/New Zealand: a record of Neogene strike-slip displacement, convergence, and basement exhumation along the Australian-Pacific plate boundary
Sagar, Matthew W., Higgs, Karen E., Strogen, Dominic P., Bland, Kyle J., Browne, Greg H.
Published in New Zealand journal of geology and geophysics (02.01.2024)
Published in New Zealand journal of geology and geophysics (02.01.2024)
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Journal Article
Baricitinib-associated changes in global gene expression during a 24-week phase II clinical systemic lupus erythematosus trial implicates a mechanism of action through multiple immune-related pathways
Dörner, Thomas, Tanaka, Yoshiya, Petri, Michelle A, Smolen, Josef S, Wallace, Daniel J, Dow, Ernst R, Higgs, Richard E, Rocha, Guilherme, Crowe, Brenda, Benschop, Robert J, Byers, Nicole L, Silk, Maria E, de Bono, Stephanie, Fantini, Damiano, Hoffman, Robert W
Published in Lupus science & medicine (09.10.2020)
Published in Lupus science & medicine (09.10.2020)
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Journal Article
Characteristic Physical Properties and Structural Fragments of Marketed Oral Drugs
Vieth, Michal, Siegel, Miles G, Higgs, Richard E, Watson, Ian A, Robertson, Daniel H, Savin, Kenneth A, Durst, Gregory L, Hipskind, Philip A
Published in Journal of medicinal chemistry (01.01.2004)
Published in Journal of medicinal chemistry (01.01.2004)
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Journal Article
Evaluation of the Relative Performance of Drug-Induced Skeletal Muscle Injury Biomarkers in Rats
Burch, Peter M, Greg Hall, David, Walker, Elizabeth G, Bracken, William, Giovanelli, Richard, Goldstein, Richard, Higgs, Richard E, King, Nicholas M P, Lane, Pamela, Sauer, John-Michael, Michna, Laura, Muniappa, Nagaraja, Pritt, Michael L, Vlasakova, Katerina, Watson, David E, Wescott, Debra, Zabka, Tanja S, Glaab, Warren E
Published in Toxicological sciences (01.03.2016)
Published in Toxicological sciences (01.03.2016)
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Journal Article
Mechanism of baricitinib supports artificial intelligence-predicted testing inCOVID-19 patients
Stebbing, J, Krishnan, V, de, Bono S, Ottaviani, S, Casalini, G, Richardson, PJ, Monteil, V, Lauschke, VM, Mirazimi, A, Youhanna, S
Published in EMBO molecular medicine (07.08.2020)
Published in EMBO molecular medicine (07.08.2020)
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Journal Article
Kinomics—structural biology and chemogenomics of kinase inhibitors and targets
Vieth, Michal, Higgs, Richard E., Robertson, Daniel H., Shapiro, Michael, Gragg, Ellen A., Hemmerle, Horst
Published in BBA - Proteins and Proteomics (11.03.2004)
Published in BBA - Proteins and Proteomics (11.03.2004)
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Book Review
Journal Article
Further Evaluation of Mechanisms Associated with the Antidepressantlike Signature of Scopolamine in Mice
Martin, Anna E, Schober, Douglas A, Nikolayev, Alexander, Tolstikov, Vladimir V, Anderson, Wesley H, Higgs, Richard E, Kuo, Ming-Shang, Laksmanan, Anastasia, Catlow, John T, Li, Xia, Felder, Christian C, Witkin, Jeffrey M
Published in CNS & neurological disorders drug targets (01.01.2017)
Published in CNS & neurological disorders drug targets (01.01.2017)
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Journal Article
Cranial meningiomas in 411 neurofibromatosis type 2 (NF2) patients with proven gene mutations: clear positional effect of mutations, but absence of female severity effect on age at onset
Smith, Miriam J, Higgs, Jenny E, Bowers, Naomi L, Halliday, Dorothy, Paterson, Joan, Gillespie, James, Huson, Susan M, Freeman, Simon R, Lloyd, Simon, Rutherford, Scott A, King, Andrew T, Wallace, Andrew J, Ramsden, Richard T, Evans, D Gareth R
Published in Journal of medical genetics (01.04.2011)
Published in Journal of medical genetics (01.04.2011)
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Journal Article