The human bile salt export pump: characterization of substrate specificity and identification of inhibitors
Byrne, Jane A, Strautnieks, Sandra S, Mieli-Vergani, Giorgina, Higgins, Christopher F, Linton, Kenneth J, Thompson, Richard J
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2002)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2002)
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Three-dimensional Structures of the Mammalian Multidrug Resistance P-glycoprotein Demonstrate Major Conformational Changes in the Transmembrane Domains upon Nucleotide Binding
Rosenberg, Mark F, Kamis, Alhaji Bukar, Callaghan, Richard, Higgins, Christopher F, Ford, Robert C
Published in The Journal of biological chemistry (07.03.2003)
Published in The Journal of biological chemistry (07.03.2003)
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Journal Article
Sequential Shrinkage and Swelling Underlie P2X7-Stimulated Lymphocyte Phosphatidylserine Exposure and Death
Taylor, Simon R. J, Gonzalez-Begne, Mireya, Dewhurst, Stephen, Chimini, Giovanna, Higgins, Christopher F, Melvin, James E, Elliott, James I
Published in The Journal of immunology (1950) (01.01.2008)
Published in The Journal of immunology (1950) (01.01.2008)
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Journal Article
Cell volume regulation and swelling-activated chloride channels
Sardini, Alessandro, Amey, Joanna S., Weylandt, Karsten-Henrich, Nobles, Muriel, Valverde, Miguel Angel, Higgins, Christopher F.
Published in BBA - Biomembranes (30.12.2003)
Published in BBA - Biomembranes (30.12.2003)
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Journal Article
P-glycoprotein (MDR1) Expression in Leukemic Cells Is Regulated at Two Distinct Steps, mRNA Stabilization and Translational Initiation
Yague, Ernesto, Armesilla, Angel L, Harrison, Georgina, Elliott, James, Sardini, Alessandro, Higgins, Christopher F, Raguz, Selina
Published in The Journal of biological chemistry (21.03.2003)
Published in The Journal of biological chemistry (21.03.2003)
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Journal Article
Phosphatidylserine exposure in B lymphocytes: a role for lipid packing
Elliott, James I., Sardini, Alessandro, Cooper, Joanne C., Alexander, Denis R., Davanture, Suzel, Chimini, Giovanna, Higgins, Christopher F.
Published in Blood (01.09.2006)
Published in Blood (01.09.2006)
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Journal Article
Role of the highly structured 5'-end region of MDR1 mRNA in P-glycoprotein expression
Randle, Rebecca A, Raguz, Selina, Higgins, Christopher F, Yagüe, Ernesto
Published in Biochemical journal (15.09.2007)
Published in Biochemical journal (15.09.2007)
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Journal Article
ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment
Weylandt, Karsten H, Nebrig, Maxim, Jansen-Rosseck, Nils, Amey, Joanna S, Carmena, David, Wiedenmann, Bertram, Higgins, Christopher F, Sardini, Alessandro
Published in Molecular cancer therapeutics (01.03.2007)
Published in Molecular cancer therapeutics (01.03.2007)
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Journal Article
A DEAD-box RNA helicase in the Escherichia coli RNA degradosome
Py, Béatrice, Higgins, Christopher F, Krisch, Henry M, Carpousis, Agamemnon J
Published in Nature (London) (09.05.1996)
Published in Nature (London) (09.05.1996)
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Journal Article
The ATP switch model for ABC transporters
Higgins, Christopher F, Linton, Kenneth J
Published in Nature structural & molecular biology (01.10.2004)
Published in Nature structural & molecular biology (01.10.2004)
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Journal Article
H-NS Oligomerization Domain Structure Reveals the Mechanism for High Order Self-association of the Intact Protein
Esposito, Diego, Petrovic, Arsen, Harris, Richard, Ono, Shusuke, Eccleston, John F., Mbabaali, Amina, Haq, Ihtshamul, Higgins, Christopher F., Hinton, Jay C.D., Driscoll, Paul C., Ladbury, John E.
Published in Journal of molecular biology (06.12.2002)
Published in Journal of molecular biology (06.12.2002)
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Journal Article
Multidrug transporter activity in lymphocytes
Elliott, James I, Raguz, Selina, Higgins, Christopher F
Published in British journal of pharmacology (01.12.2004)
Published in British journal of pharmacology (01.12.2004)
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Journal Article
human ClC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus
Okkenhaug, Hanneke, Weylandt, Karsten-Henrich, Carmena, David, Wells, Dominic J, Higgins, Christopher F, Sardini, Alessandro
Published in The FASEB journal (01.11.2006)
Published in The FASEB journal (01.11.2006)
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