Transfer of Functional Cargo in Exomeres
Zhang, Qin, Higginbotham, James N., Jeppesen, Dennis K., Yang, Yu-Ping, Li, Wei, McKinley, Eliot T., Graves-Deal, Ramona, Ping, Jie, Britain, Colleen M., Dorsett, Kaitlyn A., Hartman, Celine L., Ford, David A., Allen, Ryan M., Vickers, Kasey C., Liu, Qi, Franklin, Jeffrey L., Bellis, Susan L., Coffey, Robert J.
Published in Cell reports (Cambridge) (16.04.2019)
Published in Cell reports (Cambridge) (16.04.2019)
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Journal Article
Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS
Demory Beckler, Michelle, Higginbotham, James N., Franklin, Jeffrey L., Ham, Amy-Joan, Halvey, Patrick J., Imasuen, Imade E., Whitwell, Corbin, Li, Ming, Liebler, Daniel C., Coffey, Robert J.
Published in Molecular & cellular proteomics (01.02.2013)
Published in Molecular & cellular proteomics (01.02.2013)
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Journal Article
The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
Powell, Anne E., Wang, Yang, Li, Yina, Poulin, Emily J., Means, Anna L., Washington, Mary K., Higginbotham, James N., Juchheim, Alwin, Prasad, Nripesh, Levy, Shawn E., Guo, Yan, Shyr, Yu, Aronow, Bruce J., Haigis, Kevin M., Franklin, Jeffrey L., Coffey, Robert J.
Published in Cell (30.03.2012)
Published in Cell (30.03.2012)
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Journal Article
Amphiregulin Exosomes Increase Cancer Cell Invasion
Higginbotham, James N., Demory Beckler, Michelle, Gephart, Jonathan D., Franklin, Jeffrey L., Bogatcheva, Galina, Kremers, Gert-Jan, Piston, David W., Ayers, Gregory D., McConnell, Russell E., Tyska, Matthew J., Coffey, Robert J.
Published in Current biology (10.05.2011)
Published in Current biology (10.05.2011)
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Journal Article
KRAS-dependent sorting of miRNA to exosomes
Cha, Diana J, Franklin, Jeffrey L, Dou, Yongchao, Liu, Qi, Higginbotham, James N, Demory Beckler, Michelle, Weaver, Alissa M, Vickers, Kasey, Prasad, Nirpesh, Levy, Shawn, Zhang, Bing, Coffey, Robert J, Patton, James G
Published in eLife (01.07.2015)
Published in eLife (01.07.2015)
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Journal Article
Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells
Hinger, Scott A., Cha, Diana J., Franklin, Jeffrey L., Higginbotham, James N., Dou, Yongchao, Ping, Jie, Shu, Lihua, Prasad, Nripesh, Levy, Shawn, Zhang, Bing, Liu, Qi, Weaver, Alissa M., Coffey, Robert J., Patton, James G.
Published in Cell reports (Cambridge) (16.10.2018)
Published in Cell reports (Cambridge) (16.10.2018)
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Journal Article
Enterocyte Microvillus-Derived Vesicles Detoxify Bacterial Products and Regulate Epithelial-Microbial Interactions
Shifrin, David A., McConnell, Russell E., Nambiar, Rajalakshmi, Higginbotham, James N., Coffey, Robert J., Tyska, Matthew J.
Published in Current biology (10.04.2012)
Published in Current biology (10.04.2012)
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Journal Article
enterocyte microvillus is a vesicle-generating organelle
McConnell, Russell E, Higginbotham, James N, Shifrin, David A. Jr, Tabb, David L, Coffey, Robert J, Tyska, Matthew J
Published in The Journal of cell biology (29.06.2009)
Published in The Journal of cell biology (29.06.2009)
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Journal Article
Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting
Higginbotham, James N., Zhang, Qin, Jeppesen, Dennis K., Scott, Andrew M., Manning, H. Charles, Ochieng, Josiah, Franklin, Jeffrey L., Coffey, Robert J.
Published in Journal of extracellular vesicles (01.01.2016)
Published in Journal of extracellular vesicles (01.01.2016)
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Journal Article
Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins
Zhang, Chenguang, Huo, Xiaoye, Zhu, Yini, Higginbotham, James N., Cao, Zheng, Lu, Xin, Franklin, Jeffrey L., Vickers, Kasey C., Coffey, Robert J., Senapati, Satyajyoti, Wang, Ceming, Chang, Hsueh-Chia
Published in Communications biology (10.12.2022)
Published in Communications biology (10.12.2022)
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Journal Article
An anion exchange membrane sensor detects EGFR and its activity state in plasma CD63 extracellular vesicles from patients with glioblastoma
Maniya, Nalin H., Kumar, Sonu, Franklin, Jeffrey L., Higginbotham, James N., Scott, Andrew M., Gan, Hui K., Coffey, Robert J., Senapati, Satyajyoti, Chang, Hsueh-Chia
Published in Communications biology (03.06.2024)
Published in Communications biology (03.06.2024)
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Journal Article
Comparison of EV characterization by commercial high‐sensitivity flow cytometers and a custom single‐molecule flow cytometer
Kim, James, Xu, Shihan, Jung, Seung‐Ryoung, Nguyen, Alya, Cheng, Yuanhua, Zhao, Mengxia, Fujimoto, Bryant S., Nelson, Wyatt, Schiro, Perry, Franklin, Jeffrey L., Higginbotham, James N., Coffey, Robert J., Shi, Min, Vojtech, Lucia N., Hladik, Florian, Tewari, Muneesh, Tigges, John, Ghiran, Ionita, Jovanovic‐Talisman, Tijana, Laurent, Louise C., Das, Saumya, Gololobova, Olesia, Witwer, Kenneth W., Xu, Tuoye, Charest, Al, Jensen, Kendall Van Keuren, Raffai, Robert L., Jones, Jennifer C., Welsh, Joshua A., Nolan, John P., Chiu, Daniel T.
Published in Journal of extracellular vesicles (01.08.2024)
Published in Journal of extracellular vesicles (01.08.2024)
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Journal Article
Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells
Zhang, Qin, Jeppesen, Dennis K, Higginbotham, James N, Demory Beckler, Michelle, Poulin, Emily J, Walsh, Alex J, Skala, Melissa C, McKinley, Eliot T, Manning, H. Charles, Hight, Matthew R, Schulte, Michael L, Watt, Kimberly R, Ayers, G. Daniel, Wolf, Melissa M, Andrejeva, Gabriela, Rathmell, Jeffrey C, Franklin, Jeffrey L, Coffey, Robert J
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2018)
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Journal Article
Identification of a Novel Mono‐Leucine Basolateral Sorting Motif Within the Cytoplasmic Domain of Amphiregulin
Gephart, Jonathan D., Singh, Bhuminder, Higginbotham, James N., Franklin, Jeffrey L., Gonzalez, Alfonso, Fölsch, Heike, Coffey, Robert J.
Published in Traffic (Copenhagen, Denmark) (01.12.2011)
Published in Traffic (Copenhagen, Denmark) (01.12.2011)
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Journal Article
Comprehensive isolation of extracellular vesicles and nanoparticles
Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Franklin, Jeffrey L., Coffey, Robert J.
Published in Nature protocols (01.05.2023)
Published in Nature protocols (01.05.2023)
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Journal Article
Reassessment of Exosome Composition
Jeppesen, Dennis K., Fenix, Aidan M., Franklin, Jeffrey L., Higginbotham, James N., Zhang, Qin, Zimmerman, Lisa J., Liebler, Daniel C., Ping, Jie, Liu, Qi, Evans, Rachel, Fissell, William H., Patton, James G., Rome, Leonard H., Burnette, Dylan T., Coffey, Robert J.
Published in Cell (04.04.2019)
Published in Cell (04.04.2019)
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Journal Article
Differential in Vivo Sensitivity to Inhibition of P-glycoprotein Located in Lymphocytes, Testes, and the Blood-Brain Barrier
Choo, Edna F, Kurnik, Daniel, Muszkat, Mordechai, Ohkubo, Tadashi, Shay, Sheila D, Higginbotham, James N, Glaeser, Hartmut, Kim, Richard B, Wood, Alastair J J, Wilkinson, Grant R
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
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Journal Article
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes
Dou, Yongchao, Cha, Diana J., Franklin, Jeffrey L., Higginbotham, James N., Jeppesen, Dennis K., Weaver, Alissa M., Prasad, Nripesh, Levy, Shawn, Coffey, Robert J., Patton, James G., Zhang, Bing
Published in Scientific reports (28.11.2016)
Published in Scientific reports (28.11.2016)
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Journal Article
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Graves-Deal, Ramona, Trinh, Vincent Q., Ramirez, Marisol A., Sohn, Yoojin, Neininger, Abigail C., Taneja, Nilay, McKinley, Eliot T., Niitsu, Hiroaki, Cao, Zheng, Evans, Rachel, Glass, Sarah E., Ray, Kevin C., Fissell, William H., Hill, Salisha, Rose, Kristie Lindsey, Huh, Won Jae, Washington, Mary Kay, Ayers, Gregory Daniel, Burnette, Dylan T., Sharma, Shivani, Rome, Leonard H., Franklin, Jeffrey L., Lee, Youngmin A., Liu, Qi, Coffey, Robert J.
Published in Nature cell biology (01.12.2021)
Published in Nature cell biology (01.12.2021)
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