Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase
Palmieri, Erika M., Gonzalez-Cotto, Marieli, Baseler, Walter A., Davies, Luke C., Ghesquière, Bart, Maio, Nunziata, Rice, Christopher M., Rouault, Tracey A., Cassel, Teresa, Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M., Wink, David A., McVicar, Daniel W.
Published in Nature communications (04.02.2020)
Published in Nature communications (04.02.2020)
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The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type
Yuneva, Mariia O., Fan, Teresa W.M., Allen, Thaddeus D., Higashi, Richard M., Ferraris, Dana V., Tsukamoto, Takashi, Matés, José M., Alonso, Francisco J., Wang, Chunmei, Seo, Youngho, Chen, Xin, Bishop, J. Michael
Published in Cell metabolism (08.02.2012)
Published in Cell metabolism (08.02.2012)
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Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells
Xie, Han, Hanai, Jun-ichi, Ren, Jian-Guo, Kats, Lev, Burgess, Kerri, Bhargava, Parul, Signoretti, Sabina, Billiard, Julia, Duffy, Kevin J., Grant, Aaron, Wang, Xiaoen, Lorkiewicz, Pawel K., Schatzman, Sabrina, Bousamra, Michael, Lane, Andrew N., Higashi, Richard M., Fan, Teresa W.M., Pandolfi, Pier Paolo, Sukhatme, Vikas P., Seth, Pankaj
Published in Cell metabolism (06.05.2014)
Published in Cell metabolism (06.05.2014)
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Journal Article
Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM)
Bruntz, Ronald C., Lane, Andrew N., Higashi, Richard M., Fan, Teresa W.-M.
Published in The Journal of biological chemistry (14.07.2017)
Published in The Journal of biological chemistry (14.07.2017)
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Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
Le, Anne, Lane, Andrew N., Hamaker, Max, Bose, Sminu, Gouw, Arvin, Barbi, Joseph, Tsukamoto, Takashi, Rojas, Camilio J., Slusher, Barbara S., Zhang, Haixia, Zimmerman, Lisa J., Liebler, Daniel C., Slebos, Robbert J.C., Lorkiewicz, Pawel K., Higashi, Richard M., Fan, Teresa W.M., Dang, Chi V.
Published in Cell metabolism (04.01.2012)
Published in Cell metabolism (04.01.2012)
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De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues
Fan, Teresa W.M., Bruntz, Ronald C., Yang, Ye, Song, Huan, Chernyavskaya, Yelena, Deng, Pan, Zhang, Yan, Shah, Parag P., Beverly, Levi J., Qi, Zhen, Mahan, Angela L., Higashi, Richard M., Dang, Chi V., Lane, Andrew N.
Published in The Journal of biological chemistry (06.09.2019)
Published in The Journal of biological chemistry (06.09.2019)
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Acute loss of iron–sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells
Crooks, Daniel R., Maio, Nunziata, Lane, Andrew N., Jarnik, Michal, Higashi, Richard M., Haller, Ronald G., Yang, Ye, Fan, Teresa W-M., Linehan, W. Marston, Rouault, Tracey A.
Published in The Journal of biological chemistry (25.05.2018)
Published in The Journal of biological chemistry (25.05.2018)
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Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing
Sun, Ramon C., Fan, Teresa W.-M., Deng, Pan, Higashi, Richard M., Lane, Andrew N., Le, Anh-Thu, Scott, Timothy L., Sun, Qiushi, Warmoes, Marc O., Yang, Ye
Published in Nature communications (21.11.2017)
Published in Nature communications (21.11.2017)
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Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies
Daneshmandi, Saeed, Choi, Jee Eun, Yan, Qi, MacDonald, Cameron R., Pandey, Manu, Goruganthu, Mounika, Roberts, Nathan, Singh, Prashant K., Higashi, Richard M., Lane, Andrew N., Fan, Teresa W-M., Wang, Jianmin, McCarthy, Philip L., Repasky, Elizabeth A., Mohammadpour, Hemn
Published in Nature communications (30.03.2024)
Published in Nature communications (30.03.2024)
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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function
Daneshmandi, Saeed, Cassel, Teresa, Lin, Penghui, Higashi, Richard M., Wulf, Gerburg M., Boussiotis, Vassiliki A., Fan, Teresa W.-M., Seth, Pankaj
Published in Cell reports (Cambridge) (09.03.2021)
Published in Cell reports (Cambridge) (09.03.2021)
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Knockdown of Malic Enzyme 2 Suppresses Lung Tumor Growth, Induces Differentiation and Impacts PI3K/AKT Signaling
Ren, Jian-Guo, Seth, Pankaj, Clish, Clary B., Lorkiewicz, Pawel K., Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M., Sukhatme, Vikas P.
Published in Scientific reports (24.06.2014)
Published in Scientific reports (24.06.2014)
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Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues
Fan, Teresa Wm, Higashi, Richard M, Song, Huan, Daneshmandi, Saeed, Mahan, Angela L, Purdom, Matthew S, Bocklage, Therese J, Pittman, Thomas A, He, Daheng, Wang, Chi, Lane, Andrew N
Published in eLife (18.08.2021)
Published in eLife (18.08.2021)
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NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics
Lin, Penghui, Dai, Li, Crooks, Daniel R, Neckers, Leonard M, Higashi, Richard M, Fan, Teresa W-M, Lane, Andrew N
Published in Metabolites (29.03.2021)
Published in Metabolites (29.03.2021)
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Journal Article
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer
Fan, Teresa W-M, Winnike, Jason, Al-Attar, Ahmad, Belshoff, Alexander C, Lorkiewicz, Pawel K, Tan, Jin Lian, Wu, Min, Higashi, Richard M, Lane, Andrew N
Published in Metabolites (21.06.2023)
Published in Metabolites (21.06.2023)
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Journal Article
Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry
Gori, Sadakatali S., Lorkiewicz, Pawel, Ehringer, Daniel S., Belshoff, Alex C., Higashi, Richard M., Fan, Teresa W.-M., Nantz, Michael H.
Published in Analytical and bioanalytical chemistry (01.07.2014)
Published in Analytical and bioanalytical chemistry (01.07.2014)
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