CRISPR/Cas9-mediated gene correction in hemophilia B patient-derived iPSCs
Morishige, Satoshi, Mizuno, Shinichi, Ozawa, Hidetoshi, Nakamura, Takayuki, Mazahery, Ahmad, Nomura, Kei, Seki, Ritsuko, Mouri, Fumihiko, Osaki, Koichi, Yamamura, Kenichi, Okamura, Takashi, Nagafuji, Koji
Published in International journal of hematology (01.02.2020)
Published in International journal of hematology (01.02.2020)
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Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells
Saito, Yoriko, Kitamura, Hiroshi, Hijikata, Atsushi, Tomizawa-Murasawa, Mariko, Tanaka, Satoshi, Takagi, Shinsuke, Uchida, Naoyuki, Suzuki, Nahoko, Sone, Akiko, Najima, Yuho, Ozawa, Hidetoshi, Wake, Atsushi, Taniguchi, Shuichi, Shultz, Leonard D, Ohara, Osamu, Ishikawa, Fumihiko
Published in Science translational medicine (03.02.2010)
Published in Science translational medicine (03.02.2010)
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Beneficial tyrosine kinase inhibitor therapy in a patient with relapsed BCR-ABL1-like acute lymphoblastic leukemia with CCDC88C-PDGFRB fusion
Oya, Shuki, Morishige, Satoshi, Ozawa, Hidetoshi, Sasaki, Kensuke, Semba, Yuichiro, Yamasaki, Yoshitaka, Nakamura, Takayuki, Aoyama, Kazutoshi, Seki, Ritsuko, Mouri, Fumihiko, Osaki, Koichi, Miyamoto, Toshihiro, Maeda, Takahiro, Nagafuji, Koji
Published in International journal of hematology (01.02.2021)
Published in International journal of hematology (01.02.2021)
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The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages
Iwasaki, Hiromi, Mizuno, Shin-ichi, Arinobu, Yojiro, Ozawa, Hidetoshi, Mori, Yasuo, Shigematsu, Hirokazu, Takatsu, Kiyoshi, Tenen, Daniel G, Akashi, Koichi
Published in Genes & development (01.11.2006)
Published in Genes & development (01.11.2006)
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Developmental Checkpoints of the Basophil/Mast Cell Lineages in Adult Murine Hematopoiesis
Yojiro Arinobu, Iwasaki, Hiromi, Gurish, Michael F., Mizuno, Shin-ichi, Hirokazu Shigematsu, Hidetoshi Ozawa, Tenen, Daniel G., Austen, K. Frank, Akashi, Koichi
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (13.12.2005)
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Notch1 expression is regulated at the post-transcriptional level by the 3′ untranslated region in hematopoietic stem cell development
Mizuno, Shinichi, Iino, Tadafumi, Ozawa, Hidetoshi, Arinobu, Yojiro, Chong, Yong, Akashi, Koichi
Published in International journal of hematology (01.03.2018)
Published in International journal of hematology (01.03.2018)
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P473: CRISPR/CAS9 GENE EDITING CLARIFIES THE ROLE OF CD33 SNP RS12459419 IN GEMTUZUMAB OZOGAMICIN‐MEDIATED CYTOTOXICITY
Oya, Shuki, Ozawa, Hidetoshi, Nakamura, Takayuki, Maehiro, Yoshimi, Takaki, Yusuke, Fukuyama, Yoshinobu, Yamasaki, Yoshitaka, Yamaguchi, Maki, Aoyama, Kazutoshi, Mouri, Fumihiko, Nagafuji, Koji
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis
An, Jun, Fujiwara, Hiroshi, Suemori, Koichiro, Niiya, Toshiyuki, Azuma, Taichi, Tanimoto, Kazushi, Ochi, Toshiki, Akatsuka, Yoshiki, Mineno, Junichi, Ozawa, Hidetoshi, Ishikawa, Fumihiko, Kuzushima, Kiyotaka, Yasukawa, Masaki
Published in International journal of hematology (01.02.2011)
Published in International journal of hematology (01.02.2011)
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CD33 rs12459419 SNP Regulated the Total CD33 Expression Level
Oya, Shuki, Ozawa, Hidetoshi, Nakamura, Takayuki, Fukuyama, Toshinobu, Takaki, Yusuke, Yamasaki, Yoshitaka, Aoyama, Kazutoshi, Yamaguchi, Maki, Mouri, Fumihiko, Nagafuji, Koji
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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High-dose cytarabine plus gemtuzumab ozogamicin as consolidation therapy in patients with favorable- or intermediate-risk acute myeloid leukemia
Oya, Shuki, Ozawa, Hidetoshi, Morishige, Satoshi, Maehiro, Yoshimi, Umeda, Masahiro, Takaki, Yusuke, Fukuyama, Toshinobu, Yamasaki, Yoshitaka, Nakamura, Takayuki, Yamaguchi, Maki, Aoyama, Kazutoshi, Mouri, Fumihiko, Nagafuji, Koji
Published in International journal of hematology (01.09.2024)
Published in International journal of hematology (01.09.2024)
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CRISPR/Cas9 gene editing clarifies the role of CD33 SNP rs12459419 in gemtuzumab ozogamicin-mediated cytotoxicity
Oya, Shuki, Ozawa, Hidetoshi, Nakamura, Takayuki, Mori, Akira, Ochi, Sorahiko, Maehiro, Yoshimi, Umeda, Masahiro, Takaki, Yusuke, Fukuyama, Toshinobu, Yamasaki, Yoshitaka, Yamaguchi, Maki, Aoyama, Kazutoshi, Mouri, Fumihiko, Nagafuji, Koji
Published in International journal of hematology (01.08.2024)
Published in International journal of hematology (01.08.2024)
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Correlation of ex vivo and in vivo ammonia production with L-asparaginase biological activity in adults with lymphoid malignancies
Nakamura, Takayuki, Oya, Shuki, Ozawa, Hidetoshi, Maehiro, Yoshimi, Muta, Seiya, Umeda, Masahiro, Takaki, Yusuke, Fukuyama, Toshinobu, Yamasaki, Yoshitaka, Yamaguchi, Maki, Aoyama, Kazutoshi, Mouri, Fumihiko, Naito, Yoshiki, Nagafuji, Koji
Published in International journal of hematology (01.04.2024)
Published in International journal of hematology (01.04.2024)
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Alternating venetoclax/azacytidine and FLT3 inhibitor treatment for NPM1- and FLT3-mutated acute myeloid leukemia
Oya, Shuki, Ozawa, Hidetoshi, Maehiro, Yoshimi, Nakamura, Takayuki, Takaki, Yusuke, Fukuyama, Toshinobu, Yamasaki, Yoshitaka, Yamaguchi, Maki, Aoyama, Kazutoshi, Mouri, Fumihiko, Nagafuji, Koji
Published in Leukemia research (01.07.2023)
Published in Leukemia research (01.07.2023)
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IKZF1plus alterations are not associated with outcomes in Philadelphia‐positive acute lymphoblastic leukemia patients enrolled in the FBMTG ALL/MRD2008 trial
Ito, Yoshikiyo, Ozawa, Hidetoshi, Eto, Tetsuya, Miyamoto, Toshihiro, Kamimura, Tomohiko, Ogawa, Ryosuke, Uchida, Naoyuki, Wake, Atsusi, Fujisaki, Tomoaki, Ohno, Yuju, Takase, Ken, Okumura, Hirokazu, Takamatsu, Yasushi, Kawano, Noriaki, Akashi, Koichi, Nagafuji, Koji
Published in European journal of haematology (01.07.2023)
Published in European journal of haematology (01.07.2023)
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IKZF1 plus alterations are not associated with outcomes in Philadelphia-positive acute lymphoblastic leukemia patients enrolled in the FBMTG ALL/MRD2008 trial
Ito, Yoshikiyo, Ozawa, Hidetoshi, Eto, Tetsuya, Miyamoto, Toshihiro, Kamimura, Tomohiko, Ogawa, Ryosuke, Uchida, Naoyuki, Wake, Atsusi, Fujisaki, Tomoaki, Ohno, Yuju, Takase, Ken, Okumura, Hirokazu, Takamatsu, Yasushi, Kawano, Noriaki, Akashi, Koichi, Nagafuji, Koji
Published in European journal of haematology (01.07.2023)
Published in European journal of haematology (01.07.2023)
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A Functional Analysis of SNP on Anthracycline-Induced Cardiotoxicity in a Uniform Genetic Background Using CRISPR/Cas9 Mediated Single-Base-Edited iPSCs
Nakamura, Takayuki, Mizuno, Shinichi, Ozawa, Hidetoshi, Yamasaki, Yoshitaka, Oya, Shuki, Morishige, Satoshi, Aoyama, Kazutoshi, Ymaguchi, Maki, Seki, Ritsuko, Mouri, Fumihiko, Osaki, Koichi, Nagafuji, Koji
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Successful correction of factor V deficiency of patient‐derived iPSCs by CRISPR/Cas9‐mediated gene editing
Nakamura, Takayuki, Morishige, Satoshi, Ozawa, Hidetoshi, Kuboyama, Kenji, Yamasaki, Yoshitaka, Oya, Shuki, Yamaguchi, Maki, Aoyama, Kazutoshi, Seki, Ritsuko, Mouri, Fumihiko, Osaki, Koichi, Okamura, Takashi, Mizuno, Shinichi, Nagafuji, Koji
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2020)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.09.2020)
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CRISPR/Cas9 Mediated Gene Repair in Inherited Bleeding Disorders
Morishige, Satoshi, Ozawa, Hidetoshi, Mizuno, Shinichi, Koteda, Satoko, Kawaguchi, Kuniki, Nakamura, Takayuki, Nomura, Kei, Takeda, Harumi, Takata, Yuka, Seki, Ritsuko, Mouri, Fumihiko, Osaki, Koichi, Hashiguchi, Michitoshi, Yoshimoto, Koji, Okamura, Takashi, Nagafuji, Koji
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Amphiphysin I but not dynamin I nor synaptojanin mRNA expression increased after repeated methamphetamine administration in the rat cerebrum and cerebellum
Hamamura, Mitsuko, Okouchi, Jiro, Ozawa, Hidetoshi, Kimuro, Yoshihiko, Iwaki, Akiko, Fukumaki, Yasuyuki
Published in Journal of Neural Transmission (01.07.2013)
Published in Journal of Neural Transmission (01.07.2013)
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