Keratin 16 regulates innate immunity in response to epidermal barrier breach
Lessard, Juliane C., Piña-Paz, Sylvia, Rotty, Jeremy D., Hickerson, Robyn P., Kaspar, Roger L., Balmain, Allan, Coulombe, Pierre A.
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.11.2013)
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Journal Article
In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles
Lobovkina, Tatsiana, Jacobson, Gunilla B, Gonzalez-Gonzalez, Emilio, Hickerson, Robyn P, Leake, Devin, Kaspar, Roger L, Contag, Christopher H, Zare, Richard N
Published in ACS nano (27.12.2011)
Published in ACS nano (27.12.2011)
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Journal Article
Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells
Geihe, Erika I, Cooley, Christina B, Simon, Jeff R, Kiesewetter, Matthew K, Edward, Justin A, Hickerson, Robyn P, Kaspar, Roger L, Hedrick, James L, Waymouth, Robert M, Wender, Paul A
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2012)
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Journal Article
Following movement of the L1 stalk between three functional states in single ribosomes
Cornish, Peter V, Ermolenko, Dmitri N, Staple, David W, Hoang, Lee, Hickerson, Robyn P, Noller, Harry F, Ha, Taekjip
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (24.02.2009)
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Journal Article
First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder
Leachman, Sancy A, Hickerson, Robyn P, Schwartz, Mary E, Bullough, Emily E, Hutcherson, Stephen L, Boucher, Kenneth M, Hansen, C David, Eliason, Mark J, Srivatsa, G Susan, Kornbrust, Douglas J, Smith, Frances JD, McLean, WH Irwin, Milstone, Leonard M, Kaspar, Roger L
Published in Molecular therapy (01.02.2010)
Published in Molecular therapy (01.02.2010)
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Journal Article
Therapeutic Prospects of Exon Skipping for Epidermolysis Bullosa
Vermeer, Franciscus C, Bremer, Jeroen, Sietsma, Robert J, Sandilands, Aileen, Hickerson, Robyn P, Bolling, Marieke C, Pasmooij, Anna M G, Lemmink, Henny H, Swertz, Morris A, Knoers, Nine V A M, van der Velde, K Joeri, van den Akker, Peter C
Published in International journal of molecular sciences (12.11.2021)
Published in International journal of molecular sciences (12.11.2021)
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Journal Article
A Tensioned Human Skin Explant Model Used for Preliminary Assessment of Chemexfoliant-Stimulated Bioeffects
Conneely, Michael J., Namkoong, Jin, Allison, Francis, Hirata Tsutsumi, S. Kyoko, Grussu, Dominic, Willis, Ryan, Henderson, Kyle, Campbell, Paul A., Moy, Melissa, Lesniak, Ewelina, Wu, Joanna, Hickerson, Robyn P.
Published in JID innovations (01.01.2025)
Published in JID innovations (01.01.2025)
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Journal Article
Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita
Leachman, Sancy A, Hickerson, Robyn P, Hull, Peter R, Smith, Frances J.D, Milstone, Leonard M, Lane, E. Birgitte, Bale, Sherri J, Roop, Dennis R, McLean, W.H. Irwin, Kaspar, Roger L
Published in Journal of dermatological science (01.09.2008)
Published in Journal of dermatological science (01.09.2008)
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Journal Article
Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model
Hickerson, Robyn P., Flores, Manuel A., Leake, Devin, Lara, Maria F., Contag, Christopher H., Leachman, Sancy A., Kaspar, Roger L.
Published in Journal of investigative dermatology (01.05.2011)
Published in Journal of investigative dermatology (01.05.2011)
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Journal Article
Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients
Hickerson, Robyn P, Leake, Devin, Pho, Lana N, Leachman, Sancy A, Kaspar, Roger L
Published in Journal of dermatological science (01.11.2009)
Published in Journal of dermatological science (01.11.2009)
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Journal Article
Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays
Lara, Maria Fernanda, González-González, Emilio, Speaker, Tycho J, Hickerson, Robyn P, Leake, Devin, Milstone, Leonard M, Contag, Christopher H, Kaspar, Roger L
Published in Human gene therapy (01.08.2012)
Published in Human gene therapy (01.08.2012)
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Journal Article
Gene expression profiling in pachyonychia congenita skin
Cao, Yu-An, Hickerson, Robyn P, Seegmiller, Brandon L, Grapov, Dmitry, Gross, Maren M, Bessette, Marc R, Phinney, Brett S, Flores, Manuel A, Speaker, Tycho J, Vermeulen, Annaleen, Bravo, Albert A, Bruckner, Anna L, Milstone, Leonard M, Schwartz, Mary E, Rice, Robert H, Kaspar, Roger L
Published in Journal of dermatological science (01.03.2015)
Published in Journal of dermatological science (01.03.2015)
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Journal Article
Development of Therapeutic siRNAs for Pachyonychia Congenita
Smith, Frances J.D., Hickerson, Robyn P., Sayers, Jane M., Reeves, Robert E., Contag, Christopher H., Leake, Devin, Kaspar, Roger L., Irwin McLean, W.H.
Published in Journal of investigative dermatology (01.01.2008)
Published in Journal of investigative dermatology (01.01.2008)
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Journal Article
Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding
Llano-Sotelo, Beatriz, Hickerson, Robyn P, Lancaster, Laura, Noller, Harry F, Mankin, Alexander S
Published in RNA (Cambridge) (01.08.2009)
Published in RNA (Cambridge) (01.08.2009)
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Journal Article
Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device
Hickerson, Robyn P, Wey, Winston C, Rimm, David L, Speaker, Tycho, Suh, Susie, Flores, Manuel A, Gonzalez-Gonzalez, Emilio, Leake, Devin, Contag, Christopher H, Kaspar, Roger L
Published in Molecular therapy. Nucleic acids (01.10.2013)
Published in Molecular therapy. Nucleic acids (01.10.2013)
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Journal Article
Sequence and Stacking Dependence of 8-Oxoguanine Oxidation: Comparison of One-Electron vs Singlet Oxygen Mechanisms
Hickerson, Robyn P, Prat, Ferran, Muller, James G, Foote, Christopher S, Burrows, Cynthia J
Published in Journal of the American Chemical Society (13.10.1999)
Published in Journal of the American Chemical Society (13.10.1999)
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Journal Article
Pachyonychia Congenita: A Research Agenda Leading to New Therapeutic Approaches
O’Toole, Edel A., Kelsell, David P., Caterina, Michael J., de Brito, Marianne, Hansen, David, Hickerson, Robyn P., Hovnanian, Alain, Kaspar, Roger, Lane, E. Birgitte, Paller, Amy S., Schwartz, Janice, Shroot, Braham, Teng, Joyce, Titeux, Matthias, Coulombe, Pierre A., Sprecher, Eli
Published in Journal of investigative dermatology (01.04.2024)
Published in Journal of investigative dermatology (01.04.2024)
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Journal Article
In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation
Hegde, Vikas, Hickerson, Robyn P., Nainamalai, Sitheswaran, Campbell, Paul A., Smith, Frances J.D., McLean, W.H. Irwin, Leslie Pedrioli, Deena M.
Published in Journal of controlled release (28.12.2014)
Published in Journal of controlled release (28.12.2014)
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