A guide to time‐resolved structural analysis of light‐activated proteins
Poddar, Harshwardhan, Heyes, Derren J., Schirò, Giorgio, Weik, Martin, Leys, David, Scrutton, Nigel S.
Published in The FEBS journal (01.02.2022)
Published in The FEBS journal (01.02.2022)
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Journal Article
Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis
Zhang, Shaowei, Heyes, Derren J., Feng, Lingling, Sun, Wenli, Johannissen, Linus O., Liu, Huanting, Levy, Colin W., Li, Xuemei, Yang, Ji, Yu, Xiaolan, Lin, Min, Hardman, Samantha J. O., Hoeven, Robin, Sakuma, Michiyo, Hay, Sam, Leys, David, Rao, Zihe, Zhou, Aiwu, Cheng, Qi, Scrutton, Nigel S.
Published in Nature (London) (01.10.2019)
Published in Nature (London) (01.10.2019)
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Journal Article
Catalytic Mechanism of Aromatic Nitration by Cytochrome P450 TxtE: Involvement of a Ferric-Peroxynitrite Intermediate
Louka, Savvas, Barry, Sarah M, Heyes, Derren J, Mubarak, M. Qadri E, Ali, Hafiz Saqib, Alkhalaf, Lona M, Munro, Andrew W, Scrutton, Nigel S, Challis, Gregory L, de Visser, Sam P
Published in Journal of the American Chemical Society (16.09.2020)
Published in Journal of the American Chemical Society (16.09.2020)
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Journal Article
Enzymatic Carboxylation of 2‑Furoic Acid Yields 2,5-Furandicarboxylic Acid (FDCA)
Payne, Karl A.P, Marshall, Stephen A, Fisher, Karl, Cliff, Matthew J, Cannas, Diego M, Yan, Cunyu, Heyes, Derren J, Parker, David A, Larrosa, Igor, Leys, David
Published in ACS catalysis (05.04.2019)
Published in ACS catalysis (05.04.2019)
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Journal Article
Structural basis of kynurenine 3-monooxygenase inhibition
Amaral, Marta, Levy, Colin, Heyes, Derren J., Lafite, Pierre, Outeiro, Tiago F., Giorgini, Flaviano, Leys, David, Scrutton, Nigel S.
Published in Nature (London) (18.04.2013)
Published in Nature (London) (18.04.2013)
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Journal Article
Redox driven B12-ligand switch drives CarH photoresponse
Poddar, Harshwardhan, Rios-Santacruz, Ronald, Heyes, Derren J., Shanmugam, Muralidharan, Brookfield, Adam, Johannissen, Linus O., Levy, Colin W., Jeffreys, Laura N., Zhang, Shaowei, Sakuma, Michiyo, Colletier, Jacques-Philippe, Hay, Sam, Schirò, Giorgio, Weik, Martin, Scrutton, Nigel S., Leys, David
Published in Nature communications (21.08.2023)
Published in Nature communications (21.08.2023)
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Journal Article
Active Intermediates in Copper Nitrite Reductase Reactions Probed by a Cryotrapping‐Electron Paramagnetic Resonance Approach
Hedison, Tobias M., Shanmugam, Muralidharan, Heyes, Derren J., Edge, Ruth, Scrutton, Nigel S.
Published in Angewandte Chemie International Edition (10.08.2020)
Published in Angewandte Chemie International Edition (10.08.2020)
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Journal Article
Photocobilins integrate B12 and bilin photochemistry for enzyme control
Zhang, Shaowei, Jeffreys, Laura N., Poddar, Harshwardhan, Yu, Yuqi, Liu, Chuanyang, Patel, Kaylee, Johannissen, Linus O., Zhu, Lingyun, Cliff, Matthew J., Yan, Cunyu, Schirò, Giorgio, Weik, Martin, Sakuma, Michiyo, Levy, Colin W., Leys, David, Heyes, Derren J., Scrutton, Nigel S.
Published in Nature communications (28.03.2024)
Published in Nature communications (28.03.2024)
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Journal Article
Quantum Biology: An Update and Perspective
Kim, Youngchan, Bertagna, Federico, D’Souza, Edeline M., Heyes, Derren J., Johannissen, Linus O., Nery, Eveliny T., Pantelias, Antonio, Sanchez-Pedreño Jimenez, Alejandro, Slocombe, Louie, Spencer, Michael G., Al-Khalili, Jim, Engel, Gregory S., Hay, Sam, Hingley-Wilson, Suzanne M., Jeevaratnam, Kamalan, Jones, Alex R., Kattnig, Daniel R., Lewis, Rebecca, Sacchi, Marco, Scrutton, Nigel S., Silva, S. Ravi P., McFadden, Johnjoe
Published in Quantum reports (01.03.2021)
Published in Quantum reports (01.03.2021)
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Journal Article
Single crystal spectroscopy and multiple structures from one crystal (MSOX) define catalysis in copper nitrite reductases
Rose, Samuel L., Baba, Seiki, Okumura, Hideo, Antonyuk, Svetlana V., Sasaki, Daisuke, Hedison, Tobias M., Shanmugam, Muralidharan, Heyes, Derren J., Scrutton, Nigel S., Kumasaka, Takashi, Tosha, Takehiko, Eady, Robert R., Yamamoto, Masaki, Hasnain, S. Samar
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2022)
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Journal Article
Design and fabrication of recombinant reflectin-based multilayer reflectors: bio-design engineering and photoisomerism induced wavelength modulation
Wolde-Michael, Emmanuel, Roberts, Aled D., Heyes, Derren J., Dumanli, Ahu G., Blaker, Jonny J., Takano, Eriko, Scrutton, Nigel S.
Published in Scientific reports (16.07.2021)
Published in Scientific reports (16.07.2021)
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Journal Article
Rewiring the “Push-Pull” Catalytic Machinery of a Heme Enzyme Using an Expanded Genetic Code
Ortmayer, Mary, Fisher, Karl, Basran, Jaswir, Wolde-Michael, Emmanuel M, Heyes, Derren J, Levy, Colin, Lovelock, Sarah L, Anderson, J. L. Ross, Raven, Emma L, Hay, Sam, Rigby, Stephen E. J, Green, Anthony P
Published in ACS catalysis (21.02.2020)
Published in ACS catalysis (21.02.2020)
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Journal Article
Making light work of enzyme catalysis: protochlorophyllide oxidoreductase
Heyes, Derren J., Hunter, C. Neil
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.11.2005)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.11.2005)
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Journal Article
Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics
Phillips, Robert S, Craig, Steven, Kovalevsky, Andrey, Gerlits, Oksana, Weiss, Kevin, Iorgu, Andreea I, Heyes, Derren J, Hay, Sam
Published in ACS catalysis (07.02.2020)
Published in ACS catalysis (07.02.2020)
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Journal Article
Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis
Hedison, Tobias M, Shenoy, Rajesh T, Iorgu, Andreea I, Heyes, Derren J, Fisher, Karl, Wright, Gareth S. A, Hay, Sam, Eady, Robert R, Antonyuk, Svetlana V, Hasnain, S. Samar, Scrutton, Nigel S
Published in ACS catalysis (05.07.2019)
Published in ACS catalysis (05.07.2019)
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