Stabilizing additives added during cell lysis aid in the solubilization of recombinant proteins
Leibly, David J, Nguyen, Trang Nhu, Kao, Louis T, Hewitt, Stephen N, Barrett, Lynn K, Van Voorhis, Wesley C
Published in PloS one (20.12.2012)
Published in PloS one (20.12.2012)
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Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors
Ojo, Kayode K, Pfander, Claudia, Mueller, Natascha R, Burstroem, Charlotte, Larson, Eric T, Bryan, Cassie M, Fox, Anna M W, Reid, Molly C, Johnson, Steven M, Murphy, Ryan C, Kennedy, Mark, Mann, Henning, Leibly, David J, Hewitt, Stephen N, Verlinde, Christophe L M J, Kappe, Stefan, Merritt, Ethan A, Maly, Dustin J, Billker, Oliver, Van Voorhis, Wesley C
Published in The Journal of clinical investigation (01.06.2012)
Published in The Journal of clinical investigation (01.06.2012)
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Journal Article
Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1
Larson, Eric T, Ojo, Kayode K, Murphy, Ryan C, Johnson, Steven M, Zhang, Zhongsheng, Kim, Jessica E, Leibly, David J, Fox, Anna M. W, Reid, Molly C, Dale, Edward J, Perera, B. Gayani K, Kim, Jae, Hewitt, Stephen N, Hol, Wim G. J, Verlinde, Christophe L. M. J, Fan, Erkang, Van Voorhis, Wesley C, Maly, Dustin J, Merritt, Ethan A
Published in Journal of medicinal chemistry (22.03.2012)
Published in Journal of medicinal chemistry (22.03.2012)
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Journal Article
Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head
Edwards, Thomas E, Phan, Isabelle, Abendroth, Jan, Dieterich, Shellie H, Masoudi, Amir, Guo, Wenjin, Hewitt, Stephen N, Kelley, Angela, Leibly, David, Brittnacher, Mitch J, Staker, Bart L, Miller, Samuel I, Van Voorhis, Wesley C, Myler, Peter J, Stewart, Lance J
Published in PloS one (20.09.2010)
Published in PloS one (20.09.2010)
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Journal Article
Increasing the structural coverage of tuberculosis drug targets
Baugh, Loren, Phan, Isabelle, Begley, Darren W, Clifton, Matthew C, Armour, Brianna, Dranow, David M, Taylor, Brandy M, Muruthi, Marvin M, Abendroth, Jan, Fairman, James W, Fox, David, Dieterich, Shellie H, Staker, Bart L, Gardberg, Anna S, Choi, Ryan, Hewitt, Stephen N, Napuli, Alberto J, Myers, Janette, Barrett, Lynn K, Zhang, Yang, Ferrell, Micah, Mundt, Elizabeth, Thompkins, Katie, Tran, Ngoc, Lyons-Abbott, Sally, Abramov, Ariel, Sekar, Aarthi, Serbzhinskiy, Dmitri, Lorimer, Don, Buchko, Garry W, Stacy, Robin, Stewart, Lance J, Edwards, Thomas E, Van Voorhis, Wesley C, Myler, Peter J
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2015)
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2015)
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Journal Article
Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR‐invisible structure owing to backbone dynamics
Buchko, Garry W., Hewitt, Stephen N., Van Voorhis, Wesley C., Myler, Peter J.
Published in Acta crystallographica. Section F, Structural biology communications (01.01.2018)
Published in Acta crystallographica. Section F, Structural biology communications (01.01.2018)
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Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents
Goshu, Gashaw M., Ghose, Debarati, Bain, Joy M., Pierce, Phillip G., Begley, Darren W., Hewitt, Stephen N., Udell, Hannah S., Myler, Peter J., Meganathan, R., Hagen, Timothy J.
Published in Bioorganic & medicinal chemistry letters (15.12.2015)
Published in Bioorganic & medicinal chemistry letters (15.12.2015)
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Journal Article
Backbone and side chain ¹H, ¹³C, and ¹⁵N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei
Buchko, Garry W, Hewitt, Stephen N, Napuli, Alberto J, Van Voorhis, Wesley C, Myler, Peter J
Published in Biomolecular NMR assignments (01.12.2009)
Published in Biomolecular NMR assignments (01.12.2009)
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Journal Article
Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia
Buchko, Garry W., Abendroth, Jan, Robinson, Howard, Zhang, Yanfeng, Hewitt, Stephen N., Edwards, Thomas E., Van Voorhis, Wesley C., Myler, Peter J.
Published in Journal of structural and functional genomics (01.06.2013)
Published in Journal of structural and functional genomics (01.06.2013)
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Journal Article
Structure of a CutA1 divalent-cation tolerance protein from Cryptosporidium parvum, the protozoal parasite responsible for cryptosporidiosis
Buchko, Garry W., Abendroth, Jan, Clifton, Matthew C., Robinson, Howard, Zhang, Yanfeng, Hewitt, Stephen N., Staker, Bart L., Edwards, Thomas E., Van Voorhis, Wesley C., Myler, Peter J.
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
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Journal Article
Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline
Hewitt, Stephen N., Choi, Ryan, Kelley, Angela, Crowther, Gregory J., Napuli, Alberto J., Van Voorhis, Wesley C.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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Journal Article
Backbone chemical shift assignments for the sensor domain of the Burkholderia pseudomallei histidine kinase RisS: “missing” resonances at the dimer interface
Buchko, Garry W., Edwards, Thomas E., Hewitt, Stephen N., Phan, Isabelle Q. H., Van Voorhis, Wesley C., Miller, Samuel I., Myler, Peter J.
Published in Biomolecular NMR assignments (01.10.2015)
Published in Biomolecular NMR assignments (01.10.2015)
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Journal Article
An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Davies, Douglas R., Staker, Bart L., Abendroth, Jan A., Edwards, Thomas E., Hartley, Robert, Leonard, Jess, Kim, Hidong, Rychel, Amanda L., Hewitt, Stephen N., Myler, Peter J., Stewart, Lance J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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Journal Article
Solution-state NMR structure and biophysical characterization of zinc-substituted rubredoxin B (Rv3250c) from Mycobacterium tuberculosis
Buchko, Garry W., Hewitt, Stephen N., Napuli, Alberto J., Van Voorhis, Wesley C., Myler, Peter J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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Journal Article
Solution structure of an arsenate reductase-related protein, YffB, from Brucella melitensis, the etiological agent responsible for brucellosis
Buchko, Garry W., Hewitt, Stephen N., Napuli, Alberto J., Van Voorhis, Wesley C., Myler, Peter J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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Journal Article
Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening
Begley, Darren W., Davies, Douglas R., Hartley, Robert C., Hewitt, Stephen N., Rychel, Amanda L., Myler, Peter J., Van Voorhis, Wesley C., Staker, Bart L., Stewart, Lance J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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Journal Article
Structure of a Nudix hydrolase (MutT) in the Mg2+-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever
Buchko, Garry W., Edwards, Thomas E., Abendroth, Jan, Arakaki, Tracy L., Law, Laura, Napuli, Alberto J., Hewitt, Stephen N., Van Voorhis, Wesley C., Stewart, Lance J., Staker, Bart L., Myler, Peter J.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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Journal Article
Backbone and side chain (1)H, (13)C, and (15)N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei
Buchko, Garry W, Hewitt, Stephen N, Napuli, Alberto J, Van Voorhis, Wesley C, Myler, Peter J
Published in Biomolecular NMR assignments (01.12.2009)
Published in Biomolecular NMR assignments (01.12.2009)
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Journal Article
Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever
Buchko, Garry W, Edwards, Thomas E, Abendroth, Jan, Arakaki, Tracy L, Law, Laura, Napuli, Alberto J, Hewitt, Stephen N, Van Voorhis, Wesley C, Stewart, Lance J, Staker, Bart L, Myler, Peter J
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.09.2011)
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