Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide
Grossman, Tamar R, Carrer, Michele, Shen, Lijiang, Johnson, Robert B, Hettrick, Lisa A, Henry, Scott P, Monia, Brett P, McCaleb, Michael L
Published in Molecular vision (10.08.2017)
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Published in Molecular vision (10.08.2017)
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Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice
Grossman, Tamar R, Hettrick, Lisa A, Johnson, Robert B, Hung, Gene, Peralta, Raechel, Watt, Andrew, Henry, Scott P, Adamson, Peter, Monia, Brett P, McCaleb, Michael L
Published in Immunobiology (1979) (01.06.2016)
Published in Immunobiology (1979) (01.06.2016)
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Cyclopropylamino Acid Amide as a Pharmacophoric Replacement for 2,3-Diaminopyridine. Application to the Design of Novel Bradykinin B1 Receptor Antagonists
Wood, Michael R, Schirripa, Kathy M, Kim, June J, Wan, Bang-Lin, Murphy, Kathy L, Ransom, Richard W, Chang, Raymond S. L, Tang, Cuyue, Prueksaritanont, Thomayant, Detwiler, Theodore J, Hettrick, Lisa A, Landis, Elizabeth R, Leonard, Yvonne M, Krueger, Julie A, Lewis, Sidney D, Pettibone, Douglas J, Freidinger, Roger M, Bock, Mark G
Published in Journal of medicinal chemistry (23.02.2006)
Published in Journal of medicinal chemistry (23.02.2006)
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Abstract 5561: High-affinity antisense oligonucleotides targeting Foxp3 inhibit immunosuppressive function of regulatory T-cells and produce antitumor effects in syngeneic tumor models
Sinclair, Charles, Revenko, Alexey S., Peter, Alison, Johnson, Robert B., Hettrick, Lisa A., Taylor, Molly, Staniszewska, Anna, Hughes, Adina, Sandin, Lisa, Klein, Stephanie, Watt, Andrew, Barry, Simon, Monia, Brett T., Lyne, Paul, Macleod, A Robert, Edbrooke, Mark
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 2713: Discovery and characterization of AZD8701, a high affinity antisense oligonucleotide targeting FOXP3 to relieve immunosuppression in cancer
Sinclair, Charles, Revenko, Alexey S., Johnson, R B., Peter, Alison, Taylor, Molly A., Hettrick, Lisa A., Klein, Stephanie, Solanki, Anisha, Chapman, Melissa, Yates, James, Angell, Helen K., Watt, Andrew, Gattis, Danielle, Monia, Brett P., Barry, Simon T., Lyne, Paul, Edbrooke, Mark, Goldberg, Frederick, Macleod, A R.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Cyclopropylamino acid amide as a pharmacophoric replacement for 2,3-diaminopyridine. Application to the design of novel bradykinin B-1 receptor antagonists
Wood, MR, Schirripa, KM, Kim, JJ, Wan, BL, Murphy, KL, Ransom, RW, Chang, RSL, Tang, CY, Prueksaritanont, T, Detwiler, TJ, Hettrick, LA, Landis, ER, Leonard, YM, Krueger, JA, Lewis, SD, Pettibone, DJ, Freidinger, RM, Bock, MG
Published in Journal of medicinal chemistry (23.02.2006)
Published in Journal of medicinal chemistry (23.02.2006)
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Regiospecific intestinal absorption of the HIV protease inhibitor L-735,524 in beagle dogs
Kwei, G Y, Novak, L B, Hettrick, L A, Reiss, E R, Ostovic, D, Loper, A E, Lui, C Y, Higgins, R J, Chen, I W, Lin, J H
Published in Pharmaceutical research (01.06.1995)
Published in Pharmaceutical research (01.06.1995)
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