Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404
Fàbrega-Ferrer, Montserrat, Herrera-Morandé, Alejandra, Muriel-Goñi, Sara, Pérez-Saavedra, Julia, Bueno, Paula, Castro, Victoria, Garaigorta, Urtzi, Gastaminza, Pablo, Coll, Miquel
Published in Antiviral research (01.12.2022)
Published in Antiviral research (01.12.2022)
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Kinetic characterization and phylogenetic analysis of human ADP-dependent glucokinase reveal new insights into its regulatory properties
Herrera-Morandé, Alejandra, Vallejos-Baccelliere, Gabriel, Cea, Pablo A., Zamora, Ricardo A., Cid, Dixon, Maturana, Pablo, González-Ordenes, Felipe, Castro-Fernández, Víctor, Guixé, Victoria
Published in Archives of biochemistry and biophysics (01.06.2023)
Published in Archives of biochemistry and biophysics (01.06.2023)
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Bifunctional ADP‐dependent phosphofructokinase/glucokinase activity in the order Methanococcales – biochemical characterization of the mesophilic enzyme from Methanococcus maripaludis
Castro‐Fernandez, Victor, Bravo‐Moraga, Felipe, Herrera‐Morande, Alejandra, Guixe, Victoria
Published in The FEBS journal (01.04.2014)
Published in The FEBS journal (01.04.2014)
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Crystal structure, SAXS and kinetic mechanism of hyperthermophilic ADP-dependent glucokinase from Thermococcus litoralis reveal a conserved mechanism for catalysis
Rivas-Pardo, Jaime Andrés, Herrera-Morande, Alejandra, Castro-Fernandez, Victor, Fernandez, Francisco J, Vega, M Cristina, Guixé, Victoria
Published in PloS one (20.06.2013)
Published in PloS one (20.06.2013)
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Free radicals derived from γ-radiolysis of water and AAPH thermolysis mediate oxidative crosslinking of eGFP involving Tyr-Tyr and Tyr-Cys bonds: the fluorescence of the protein is conserved only towards peroxyl radicals
Zamora, Ricardo A., Fuentes-Lemus, Eduardo, Barrias, Pablo, Herrera-Morande, Alejandra, Mura, Francisco, Guixé, Victoria, Castro-Fernandez, Victor, Rojas, Tomás, López-Alarcón, Camilo, Aguirre, Paulina, Rivas-Aravena, Andrea, Aspée, Alexis
Published in Free radical biology & medicine (01.04.2020)
Published in Free radical biology & medicine (01.04.2020)
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Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases
Castro-Fernandez, Víctor, Herrera-Morande, Alejandra, Zamora, Ricardo, Merino, Felipe, Gonzalez-Ordenes, Felipe, Padilla-Salinas, Felipe, Pereira, Humberto M., Brandão-Neto, Jose, Garratt, Richard C., Guixe, Victoria
Published in The Journal of biological chemistry (22.09.2017)
Published in The Journal of biological chemistry (22.09.2017)
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Tuning of Conformational Dynamics Through Evolution-Based Design Modulates the Catalytic Adaptability of an Extremophilic Kinase
Zamora, Ricardo A, Ramirez-Sarmiento, Cesar A, Castro-Fernández, Víctor, Villalobos, Pablo, Maturana, Pablo, Herrera-Morande, Alejandra, Komives, Elizabeth A, Guixé, Victoria
Published in ACS catalysis (02.10.2020)
Published in ACS catalysis (02.10.2020)
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Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases
Castro-Fernandez, Víctor, Herrera-Morande, Alejandra, Zamora, Ricardo, Merino, Felipe, Gonzalez-Ordenes, Felipe, Padilla-Salinas, Felipe, Pereira, Humberto M., Brandão-Neto, Jose, Garratt, Richard C., Guixe, Victoria
Published in The Journal of biological chemistry (22.12.2017)
Published in The Journal of biological chemistry (22.12.2017)
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Protein topology determines substrate-binding mechanism in homologous enzymes
Herrera-Morande, Alejandra, Castro-Fernández, Victor, Merino, Felipe, Ramírez-Sarmiento, Cesar A., Fernández, Francisco J., Vega, M. Cristina, Guixé, Victoria
Published in Biochimica et biophysica acta. General subjects (01.12.2018)
Published in Biochimica et biophysica acta. General subjects (01.12.2018)
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Bifunctional ADP ‐dependent phosphofructokinase/glucokinase activity in the order M ethanococcales – biochemical characterization of the mesophilic enzyme from M ethanococcus maripaludis
Castro‐Fernandez, Victor, Bravo‐Moraga, Felipe, Herrera‐Morande, Alejandra, Guixe, Victoria
Published in The FEBS journal (01.04.2014)
Published in The FEBS journal (01.04.2014)
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