A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity
Hernandez-Sanchez, Wilnelly, Huang, Wei, Plucinsky, Brian, Garcia-Vazquez, Nelson, Robinson, Nathaniel J, Schiemann, William P, Berdis, Anthony J, Skordalakes, Emmanuel, Taylor, Derek J
Published in PLoS biology (05.04.2019)
Published in PLoS biology (05.04.2019)
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Journal Article
POT1–TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism
Mullins, Michael R., Rajavel, Malligarjunan, Hernandez-Sanchez, Wilnelly, de la Fuente, Maria, Biendarra, Sherri M., Harris, Michael E., Taylor, Derek J.
Published in Journal of molecular biology (03.07.2016)
Published in Journal of molecular biology (03.07.2016)
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Journal Article
Abstract 2714: Inhibition of human telomerase by new purine analogs
Hernandez-Sanchez, Wilnelly M., Baus, Diane, Berdis, Anthony J., Taylor, Derek J.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
POT1-TPP1 differentially regulates telomerase via POT1 His266 and as a function of single-stranded telomere DNA length
Xu, Mengyuan, Kiselar, Janna, Whited, Tawna L., Hernandez-Sanchez, Wilnelly, Taylor, Derek J.
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (19.11.2019)
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Journal Article
A FAM83A Positive Feed-back Loop Drives Survival and Tumorigenicity of Pancreatic Ductal Adenocarcinomas
Parameswaran, Neetha, Bartel, Courtney A., Hernandez-Sanchez, Wilnelly, Miskimen, Kristy L., Smigiel, Jacob M., Khalil, Ahmad M., Jackson, Mark W.
Published in Scientific reports (16.09.2019)
Published in Scientific reports (16.09.2019)
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Journal Article
Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner
Zeng, Xuehuo, Hernandez-Sanchez, Wilnelly, Xu, Mengyuan, Whited, Tawna L., Baus, Diane, Zhang, Junran, Berdis, Anthony J., Taylor, Derek J.
Published in Cell reports (Cambridge) (05.06.2018)
Published in Cell reports (Cambridge) (05.06.2018)
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Journal Article
Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance
Rajavel, Malligarjunan, Orban, Tivadar, Xu, Mengyuan, Hernandez-Sanchez, Wilnelly, de la Fuente, Maria, Palczewski, Krzysztof, Taylor, Derek J
Published in Nucleic acids research (01.12.2016)
Published in Nucleic acids research (01.12.2016)
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Journal Article
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B
Cipriano, R, Bryson, B L, Miskimen, K L S, Bartel, C A, Hernandez-Sanchez, W, Bruntz, R C, Scott, S A, Lindsley, C W, Brown, H A, Jackson, M W
Published in Oncogene (19.06.2014)
Published in Oncogene (19.06.2014)
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