Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set
Lenselink, Eelke B., ten Dijke, Niels, Bongers, Brandon, Papadatos, George, van Vlijmen, Herman W. T., Kowalczyk, Wojtek, IJzerman, Adriaan P., van Westen, Gerard J. P.
Published in Journal of cheminformatics (14.08.2017)
Published in Journal of cheminformatics (14.08.2017)
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Journal Article
An exploration strategy improves the diversity of de novo ligands using deep reinforcement learning: a case for the adenosine A2A receptor
Liu, Xuhan, Ye, Kai, van Vlijmen, Herman W. T., IJzerman, Adriaan P., van Westen, Gerard J. P.
Published in Journal of cheminformatics (24.05.2019)
Published in Journal of cheminformatics (24.05.2019)
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Journal Article
Invited review: Microbiota of the bovine udder: Contributing factors and potential implications for udder health and mastitis susceptibility
Derakhshani, Hooman, Fehr, Kelsey B., Sepehri, Shadi, Francoz, David, De Buck, Jeroen, Barkema, Herman W., Plaizier, Jan C., Khafipour, Ehsan
Published in Journal of dairy science (01.12.2018)
Published in Journal of dairy science (01.12.2018)
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Journal Article
Use of the Michigan Neuropathy Screening Instrument as a measure of distal symmetrical peripheral neuropathy in Type 1 diabetes: results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications
Herman, W. H., Pop-Busui, R., Braffett, B. H., Martin, C. L., Cleary, P. A., Albers, J. W., Feldman, E. L.
Published in Diabetic medicine (01.07.2012)
Published in Diabetic medicine (01.07.2012)
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Journal Article
Incidence of clinical mastitis and distribution of pathogens on large Chinese dairy farms
Gao, Jian, Barkema, Herman W., Zhang, Limei, Liu, Gang, Deng, Zhaoju, Cai, Lingjie, Shan, Ruixue, Zhang, Shiyao, Zou, Jiaqi, Kastelic, John P., Han, Bo
Published in Journal of dairy science (01.06.2017)
Published in Journal of dairy science (01.06.2017)
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Journal Article
Invited review: Academic and applied approach to evaluating longevity in dairy cows
Schuster, Jesse C., Barkema, Herman W., De Vries, Albert, Kelton, David F., Orsel, Karin
Published in Journal of dairy science (01.12.2020)
Published in Journal of dairy science (01.12.2020)
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Journal Article
Economic losses due to Johne's disease (paratuberculosis) in dairy cattle
Rasmussen, Philip, Barkema, Herman W., Mason, Steve, Beaulieu, Eugene, Hall, David C.
Published in Journal of dairy science (01.03.2021)
Published in Journal of dairy science (01.03.2021)
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Journal Article
Herpesvirus Evasion of Natural Killer Cells
De Pelsmaeker, Steffi, Romero, Nicolas, Vitale, Massimo, Favoreel, Herman W
Published in Journal of virology (01.06.2018)
Published in Journal of virology (01.06.2018)
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Journal Article
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Frolkis, Alexandra D, Dykeman, Jonathan, Negrón, María E, deBruyn, Jennifer, Jette, Nathalie, Fiest, Kirsten M, Frolkis, Talia, Barkema, Herman W, Rioux, Kevin P, Panaccione, Remo, Ghosh, Subrata, Wiebe, Samuel, Kaplan, Gilaad G
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2013)
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Journal Article
The Effect of Lifestyle Intervention and Metformin on Preventing or Delaying Diabetes Among Women With and Without Gestational Diabetes: The Diabetes Prevention Program Outcomes Study 10-Year Follow-Up
Aroda, V. R, Christophi, C. A, Edelstein, S. L, Zhang, P, Herman, W. H, Barrett-Connor, E, Delahanty, L. M, Montez, M. G, Ackermann, R. T, Zhuo, X, Knowler, W. C, Ratner, R. E, for the Diabetes Prevention Program Research Group
Published in The journal of clinical endocrinology and metabolism (01.04.2015)
Published in The journal of clinical endocrinology and metabolism (01.04.2015)
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Journal Article
Advances and Challenges in Computational Target Prediction
Sydow, Dominique, Burggraaff, Lindsey, Szengel, Angelika, van Vlijmen, Herman W. T, IJzerman, Adriaan P, van Westen, Gerard J. P, Volkamer, Andrea
Published in Journal of chemical information and modeling (28.05.2019)
Published in Journal of chemical information and modeling (28.05.2019)
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Journal Article
DrugEx v2: de novo design of drug molecules by Pareto-based multi-objective reinforcement learning in polypharmacology
Liu, Xuhan, Ye, Kai, van Vlijmen, Herman W. T., Emmerich, Michael T. M., IJzerman, Adriaan P., van Westen, Gerard J. P.
Published in Journal of cheminformatics (12.11.2021)
Published in Journal of cheminformatics (12.11.2021)
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Journal Article
Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues
Shavlakadze, Tea, Morris, Melody, Fang, Jian, Wang, Sharon X., Zhu, Jiang, Zhou, Weihua, Tse, Herman W., Mondragon-Gonzalez, Ricardo, Roma, Guglielmo, Glass, David J.
Published in Cell reports (Cambridge) (17.09.2019)
Published in Cell reports (Cambridge) (17.09.2019)
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Journal Article
Application of AlphaFold models in evaluating ligandable cysteines across E3 ligases
Koldenhof, Patrick, Bemelmans, Martijn P., Ghosh, Brahma, Damm‐Ganamet, Kelly L., Vlijmen, Herman W. T., Pande, Vineet
Published in Proteins, structure, function, and bioinformatics (01.07.2024)
Published in Proteins, structure, function, and bioinformatics (01.07.2024)
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Journal Article
Genomic Selection in Aquaculture: Application, Limitations and Opportunities With Special Reference to Marine Shrimp and Pearl Oysters
Zenger, Kyall R, Khatkar, Mehar S, Jones, David B, Khalilisamani, Nima, Jerry, Dean R, Raadsma, Herman W
Published in Frontiers in genetics (23.01.2019)
Published in Frontiers in genetics (23.01.2019)
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Journal Article
Bridging the Gap: Virus Long-Distance Spread via Tunneling Nanotubes
Jansens, Robert J J, Tishchenko, Alexander, Favoreel, Herman W
Published in Journal of virology (31.03.2020)
Published in Journal of virology (31.03.2020)
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Journal Article
Alphaherpesvirus-induced activation of plasmacytoid dendritic cells depends on the viral glycoprotein gD and is inhibited by non-infectious light particles
Delva, Jonas L, Van Waesberghe, Cliff, Klupp, Barbara G, Mettenleiter, Thomas C, Favoreel, Herman W
Published in PLoS pathogens (29.11.2021)
Published in PLoS pathogens (29.11.2021)
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