Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia
Herling, Carmen D., Abedpour, Nima, Weiss, Jonathan, Schmitt, Anna, Jachimowicz, Ron Daniel, Merkel, Olaf, Cartolano, Maria, Oberbeck, Sebastian, Mayer, Petra, Berg, Valeska, Thomalla, Daniel, Kutsch, Nadine, Stiefelhagen, Marius, Cramer, Paula, Wendtner, Clemens-Martin, Persigehl, Thorsten, Saleh, Andreas, Altmüller, Janine, Nürnberg, Peter, Pallasch, Christian, Achter, Viktor, Lang, Ulrich, Eichhorst, Barbara, Castiglione, Roberta, Schäfer, Stephan C., Büttner, Reinhard, Kreuzer, Karl-Anton, Reinhardt, Hans Christian, Hallek, Michael, Frenzel, Lukas P., Peifer, Martin
Published in Nature communications (20.02.2018)
Published in Nature communications (20.02.2018)
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Early treatment with FCR versus watch and wait in patients with stage Binet A high-risk chronic lymphocytic leukemia (CLL): a randomized phase 3 trial
Herling, Carmen D., Cymbalista, Florence, Groß-Ophoff-Müller, Carolin, Bahlo, Jasmin, Robrecht, Sandra, Langerbeins, Petra, Fink, Anna-Maria, Al-Sawaf, Othman, Busch, Raymonde, Porcher, Raphael, Cazin, Bruno, Dreyfus, Brigitte, Ibach, Stefan, Leprêtre, Stéphane, Fischer, Kirsten, Kaiser, Florian, Eichhorst, Barbara, Wentner, Clemens-Martin, Hoechstetter, Manuela A., Döhner, Hartmut, Leblond, Veronique, Kneba, Michael, Letestu, Remi, Böttcher, Sebastian, Stilgenbauer, Stephan, Hallek, Michael, Levy, Vincent
Published in Leukemia (01.08.2020)
Published in Leukemia (01.08.2020)
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Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations
Pacholewska, Alicja, Lienhard, Matthias, Brueggemann, Mirko, Haenel, Heike, Bilalli, Lorina, Koenigs, Anja, Hess, Felix, Becker, Kerstin, Koehrer, Karl, Kaiser, Jesko Fabian, Gohlke, Holger, Gattermann, Norbert, Hallek, Michael, Herling, Carmen Diana, Koenig, Julian, Grimm, Christina, Herwig, Ralf, Zarnack, Kathi, Schweiger, Michal R
Published in Genome research (13.09.2024)
Published in Genome research (13.09.2024)
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Machine learning can identify newly diagnosed patients with CLL at high risk of infection
Agius, Rudi, Brieghel, Christian, Andersen, Michael A., Pearson, Alexander T., Ledergerber, Bruno, Cozzi-Lepri, Alessandro, Louzoun, Yoram, Andersen, Christen L., Bergstedt, Jacob, von Stemann, Jakob H., Jørgensen, Mette, Tang, Man-Hung Eric, Fontes, Magnus, Bahlo, Jasmin, Herling, Carmen D., Hallek, Michael, Lundgren, Jens, MacPherson, Cameron Ross, Larsen, Jan, Niemann, Carsten U.
Published in Nature communications (17.01.2020)
Published in Nature communications (17.01.2020)
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Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia ( Comment to Tausch et al. )
Weiss, Jonathan, Peifer, Martin, Herling, Carmen D, Frenzel, Lukas P, Hallek, Michael
Published in Haematologica (Roma) (01.11.2019)
Published in Haematologica (Roma) (01.11.2019)
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Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia
Jiang, Qu, Stachelscheid, Johanna, Bloehdorn, Johannes, Pacholewska, Alicja, Aszyk, Christoph, Grotenhuijs, Francien, Müller, Tony, Onder, Ozlem, Wagle, Prerana, Herling, Carmen D., Kleppe, Maria, Wang, Zhefang, Coombes, Kevin R., Robrecht, Sandra, Dalvi, Priya S., Plosnita, Bianca, Mayer, Petra, Abruzzo, Lynne V., Altmüller, Janine, Gathof, Birgit, Persigehl, Thorsten, Fischer, Kirsten, Jebaraj, Billy, Rienhoff, Hugh Y., Ecker, Rupert, Zhao, Yue, Bruns, Christiane J., Stilgenbauer, Stephan, Elenitoba-Johnson, Kojo, Hallek, Michael, Schweiger, Michal R., Odenthal, Margarete, Vasyutina, Elena, Herling, Marco
Published in Blood (06.07.2023)
Published in Blood (06.07.2023)
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Trisomy 12 chronic lymphocytic leukemia expresses a unique set of activated and targetable pathways
Abruzzo, Lynne V, Herling, Carmen D, Calin, George A, Oakes, Christopher, Barron, Lynn L, Banks, Haley E, Katju, Vikram, Keating, Michael J, Coombes, Kevin R
Published in Haematologica (Roma) (01.12.2018)
Published in Haematologica (Roma) (01.12.2018)
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B-cell acute lymphoblastic leukemia in patients with chronic lymphocytic leukemia treated with lenalidomide
Fürstenau, Moritz, Fink, Anna Maria, Schilhabel, Anke, Weiss, Jonathan, Robrecht, Sandra, Eckert, Robert, de la Serna, Javier, Crespo, Marta, Coscia, Marta, Vitale, Candida, Böttcher, Sebastian, Weppner, Gesche, Ritgen, Matthias, Stilgenbauer, Stephan, Tausch, Eugen, Fischer, Kirsten, Hallek, Michael, Eichhorst, Barbara, Brüggemann, Monika, Herling, Carmen D.
Published in Blood (22.04.2021)
Published in Blood (22.04.2021)
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Prognostic model for newly diagnosed CLL patients in Binet stage A: results of the multicenter, prospective CLL1 trial of the German CLL study group
Hoechstetter, Manuela A., Busch, Raymonde, Eichhorst, Barbara, Bühler, Andreas, Winkler, Dirk, Bahlo, Jasmin, Robrecht, Sandra, Eckart, Michael J., Vehling-Kaiser, Ursula, Jacobs, Georg, Jäger, Ulrich, Hurtz, Hans Jürgen, Hopfinger, Georg, Hartmann, Frank, Fuss, Harald, Abenhardt, Wolfgang, Blau, Ilona, Freier, Werner, Müller, Lothar, Goebeler, Maria, Wendtner, Clemens, Fischer, Kirsten, Herling, Carmen D., Starck, Michael, Bentz, Martin, Emmerich, Bertold, Döhner, Hartmut, Stilgenbauer, Stephan, Hallek, Michael
Published in Leukemia (01.04.2020)
Published in Leukemia (01.04.2020)
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Altered DNA Methylation Profiles in SF3B1 Mutated CLL Patients
Pacholewska, Alicja, Grimm, Christina, Herling, Carmen D., Lienhard, Matthias, Königs, Anja, Timmermann, Bernd, Altmüller, Janine, Mücke, Oliver, Reinhardt, Hans Christian, Plass, Christoph, Herwig, Ralf, Hallek, Michael, Schweiger, Michal R.
Published in International journal of molecular sciences (01.09.2021)
Published in International journal of molecular sciences (01.09.2021)
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Time-to-progression after front-line fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy for chronic lymphocytic leukaemia: a retrospective, multicohort study
Herling, Carmen D, Coombes, Kevin R, Benner, Axel, Bloehdorn, Johannes, Barron, Lynn L, Abrams, Zachary B, Majewski, Tadeusz, Bondaruk, Jolanta E, Bahlo, Jasmin, Fischer, Kirsten, Hallek, Michael, Stilgenbauer, Stephan, Czerniak, Bogdan A, Oakes, Christopher C, Ferrajoli, Alessandra, Keating, Michael J, Abruzzo, Lynne V
Published in The lancet oncology (01.11.2019)
Published in The lancet oncology (01.11.2019)
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Semi‐automated cancer genome analysis using high‐performance computing
Crispatzu, Giuliano, Kulkarni, Pranav, Toliat, Mohammad R., Nürnberg, Peter, Herling, Marco, Herling, Carmen D., Frommolt, Peter
Published in Human mutation (01.10.2017)
Published in Human mutation (01.10.2017)
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Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
Knittel, Gero, Rehkämper, Tim, Korovkina, Darya, Liedgens, Paul, Fritz, Christian, Torgovnick, Alessandro, Al-Baldawi, Yussor, Al-Maarri, Mona, Cun, Yupeng, Fedorchenko, Oleg, Riabinska, Arina, Beleggia, Filippo, Nguyen, Phuong-Hien, Wunderlich, F. Thomas, Ortmann, Monika, Montesinos-Rongen, Manuel, Tausch, Eugen, Stilgenbauer, Stephan, P. Frenzel, Lukas, Herling, Marco, Herling, Carmen, Bahlo, Jasmin, Hallek, Michael, Peifer, Martin, Buettner, Reinhard, Persigehl, Thorsten, Reinhardt, H. Christian
Published in Nature communications (28.07.2017)
Published in Nature communications (28.07.2017)
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Identifying patients with chronic lymphocytic leukemia without need of treatment: End of endless watch and wait?
Brieghel, Christian, Galle, Veerle, Agius, Rudi, da Cunha‐Bang, Caspar, Andersen, Michael A., Vlummens, Philip, Mattsson, Mattias, Rosenquist, Richard, Smedby, Karin E., Herling, Carmen D., Bahlo, Jasmin, Hallek, Michael, Lundgren, Jens D., Offner, Fritz, Niemann, Carsten U.
Published in European journal of haematology (01.05.2022)
Published in European journal of haematology (01.05.2022)
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Inferring clonal heterogeneity in cancer using SNP arrays and whole genome sequencing
Zucker, Mark R, Abruzzo, Lynne V, Herling, Carmen D, Barron, Lynn L, Keating, Michael J, Abrams, Zachary B, Heerema, Nyla, Coombes, Kevin R
Published in Bioinformatics (Oxford, England) (01.09.2019)
Published in Bioinformatics (Oxford, England) (01.09.2019)
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Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing
Vollbrecht, Claudia, Mairinger, Fabian Dominik, Koitzsch, Ulrike, Peifer, Martin, Koenig, Katharina, Heukamp, Lukas Carl, Crispatzu, Giuliano, Wilden, Laura, Kreuzer, Karl-Anton, Hallek, Michael, Odenthal, Margarete, Herling, Carmen Diana, Buettner, Reinhard
Published in PloS one (08.06.2015)
Published in PloS one (08.06.2015)
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Outcome of patients aged 80 years or older treated for chronic lymphocytic leukaemia
Al‐Sawaf, Othman, Bahlo, Jasmin, Robrecht, Sandra, Fischer, Kirsten, Herling, Carmen D., Hoechstetter, Manuela, Fink, Anna‐Maria, Tresckow, Julia, Langerbeins, Petra, Cramer, Paula, Stilgenbauer, Stephan, Wendtner, Clemens M., Eichhorst, Barbara, Hallek, Michael, Goede, Valentin
Published in British journal of haematology (01.12.2018)
Published in British journal of haematology (01.12.2018)
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Journal Article
Inferring clonal heterogeneity in cancer using SNP arrays and whole genome sequencing
Zucker, Mark R, Abruzzo, Lynne V, Herling, Carmen D, Barron, Lynn L, Keating, Michael J, Abrams, Zachary B, Heerema, Nyla, Coombes, Kevin R
Published in Bioinformatics (Oxford, England) (01.09.2019)
Published in Bioinformatics (Oxford, England) (01.09.2019)
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Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden
Prinz, Christian, Vasyutina, Elena, Lohmann, Gregor, Schrader, Alexandra, Romanski, Steffen, Hirschhäuser, Christoph, Mayer, Petra, Frias, Corazon, Herling, Carmen D, Hallek, Michael, Schmalz, Hans-Günther, Prokop, Aram, Mougiakakos, Dimitrios, Herling, Marco
Published in Molecular cancer (04.06.2015)
Published in Molecular cancer (04.06.2015)
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