Pharmacological and Pharmacokinetic Properties of a Structurally Novel, Potent, and Selective Metabotropic Glutamate 2/3 Receptor Agonist: In Vitro Characterization of Agonist (â)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic Acid (LY404039)
Rorick-Kehn, Linda M, Johnson, Bryan G, Burkey, Jennifer L, Wright, Rebecca A, Calligaro, David O, Marek, Gerard J, Nisenbaum, Eric S, Catlow, John T, Kingston, Ann E, Giera, Deborah D, Herin, Marc F, Monn, James A, McKinzie, David L, Schoepp, Darryle D
Published in The Journal of pharmacology and experimental therapeutics (01.04.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2007)
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Journal Article
Dipeptides as Effective Prodrugs of the Unnatural Amino Acid (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740), a Selective Group II Metabotropic Glutamate Receptor Agonist
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Published in Journal of medicinal chemistry (11.08.2005)
Published in Journal of medicinal chemistry (11.08.2005)
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PRODRUGS OF EXCITATORY AMINO ACIDS
MONN, JAMES ALLEN, MONTERO SALGADO, CARLOS, MARTIN, JOSE ALFREDO, DANTZIG, ANNE HOLLINS, VALLI, MATTHEW JOHN, BUENO MELENDO, ANA BELEN, HILLGREN, KATHLEEN MICHELE, MOHER, ERIC DAVID, DOMINGUEZ-FERNANDEZ, CARMEN, COFFEY, DAVID SCOTT, MASSEY, STEVEN MARC, PEDREGAL-TERCERO, CONCEPCION, HERIN, MARC, F, PEDERSEN, STEVEN WAYNE, SWEETANA, STEPHANIE ANN, MARTIN-CABREJAS, LUISA MARIA, DE DIOS, ALFONSO, MARTINEZ-GRAU, MARIA ANGELES
Year of Publication 15.10.2003
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Year of Publication 15.10.2003
Patent
Prodrugs of excitatory amino acids
MONN, JAMES ALLEN, MARTIN, JOSE ALFREDO, HILLGREN,KATHLEEN MICHELE, PEDEREGAL-TERCERO, CONCEPCION, DANTZIG, ANNE HOLLINS, VALLI, MATTHEW JOHN, MOHER, ERIC DAVID, DOMINGUEZ-FERNANDEZ, CARMEN, COFFEY, DAVID SCOTT, MASSEY, STEVEN MARC, MONTERO, CARLOS, BUENO, ANA BELEN, HERIN, MARC, F, PEDERSEN, STEVEN WAYNE, SWEETANA, STEPHANIE ANN, MARTIN CABREJAS, LUISA MARIA, DE DIOS, ALFONSO, MARTINEZ-GRAU, MARIA ANGELES
Year of Publication 14.05.2003
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Year of Publication 14.05.2003
Patent
PRODRUGS OF EXCITATORY AMINO ACIDS
MONTERO SALGADO, CARLOS, MARTINEZ-GRAU, MARIA, ANGELES, BUENO MELENDO, ANA, BELEN, MARTIN, JOSE, ALFREDO, MOHER, ERIC, DAVID, DANTZIG, ANNE, HOLLINS, MONN, JAMES, ALLEN, PEDERSEN, STEVEN, WAYNE, DOMINGUEZ-FERNANDEZ, CARMEN, MASSEY, STEVEN, MARC, MARTIN-CABREJAS, LUISA, MARIA, PEDREGAL-TERCERO, CONCEPCION, VALLI, MATTHEW, JOHN, HERIN, MARC, F, SWEETANA, STEPHANIE, ANN, DE DIOS, ALFONSO, HILLGREN, KATHLEEN, MICHELE, COFFEY, DAVID, SCOTT
Year of Publication 18.07.2002
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Year of Publication 18.07.2002
Patent