Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes
Herdon, H.J, Godfrey, F.M, Brown, A.M, Coulton, S, Evans, J.R, Cairns, W.J
Published in Neuropharmacology (01.07.2001)
Published in Neuropharmacology (01.07.2001)
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Characterization of a CNS penetrant, selective M 1 muscarinic receptor agonist, 77‐LH‐28‐1
Langmead, C J, Austin, N E, Branch, C L, Brown, J T, Buchanan, K A, Davies, C H, Forbes, I T, Fry, V A H, Hagan, J J, Herdon, H J, Jones, G A, Jeggo, R, Kew, J N C, Mazzali, A, Melarange, R, Patel, N, Pardoe, J, Randall, A D, Roberts, C, Roopun, A, Starr, K R, Teriakidis, A, Wood, M D, Whittington, M, Wu, Z, Watson, J
Published in British journal of pharmacology (01.07.2008)
Published in British journal of pharmacology (01.07.2008)
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Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile
Chan, Wai N, Evans, John M, Hadley, Michael S, Herdon, Hugh J, Jerman, Jeffrey C, Morgan, Helen K. A, Stean, Tania O, Thompson, Mervyn, Upton, Neil, Vong, Antonio K
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
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Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent
CHAN, W. N, EVANS, J. M, HADLEY, M. S, HERDON, H. J, JERMAN, J. C, PARSONS, A. A, READ, S. J, STEAN, T. O, THOMPSON, M, UPTON, N
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
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Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures
Upton, Neil, Blackburn, Tom P., Campbell, Colin A., Cooper, Duncan, Evans, Martyn L., Herdon, Hugh J., King, Penny D., Ray, Alison M., Stean, Tania O., Chan, Wai N., Evans, John M., Thompson, Mervyn
Published in British journal of pharmacology (01.08.1997)
Published in British journal of pharmacology (01.08.1997)
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Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes
Herdon, Hugh J., Jerman, Jeffrey C., Stean, Tania O., Middlemiss, Derek N., Chan, Wai N., Vong, Antonio K., Evans, John M., Thompson, Mervyn, Upton, Neil
Published in British journal of pharmacology (01.08.1997)
Published in British journal of pharmacology (01.08.1997)
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Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides
CHAN, W. N, HADLEY, M. S, WARD, R. W, HARLING, J. D, HERDON, H. J, ORLEK, B. S, RILEY, G. J, STEAD, R. E. A, STEAN, T. O, THOMPSON, M, UPTON, N
Published in Bioorganic & medicinal chemistry (01.08.2000)
Published in Bioorganic & medicinal chemistry (01.08.2000)
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Journal Article
Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1
Langmead, C J, Austin, N E, Branch, C L, Brown, J T, Buchanan, K A, Davies, C H, Forbes, I T, Fry, V A H, Hagan, J J, Herdon, H J, Jones, G A, Jeggo, R, Kew, J N C, Mazzali, A, Melarange, R, Patel, N, Pardoe, J, Randall, A D, Roberts, C, Roopun, A, Starr, K R, Teriakidis, A, Wood, M D, Whittington, M, Wu, Z, Watson, J
Published in British journal of pharmacology (01.07.2008)
Published in British journal of pharmacology (01.07.2008)
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Journal Article
Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity
Chan, Wai N., Hadley, Michael S, Harling, John D., Herdon, Hugh J., Jerman, Jeffrey C., Orlek, Barry S., Stean, Tania O., Thompson, Mervyn, Upton, Neil, Ward, Robert W.
Published in Bioorganic & medicinal chemistry letters (20.10.1998)
Published in Bioorganic & medicinal chemistry letters (20.10.1998)
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Characterization of the binding of [125I]‐human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor
Langmead, Christopher J, Szekeres, Philip G, Chambers, Jonathan K, Ratcliffe, Steven J, Jones, Declan N C, Hirst, Warren D, Price, Gary W, Herdon, Hugh J
Published in British journal of pharmacology (01.10.2000)
Published in British journal of pharmacology (01.10.2000)
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Effect of testosterone on gonadotrophin-releasing hormone receptors in the castrated rat: preliminary evidence for a stimulatory effect of testosterone on gonadotrophin function in the male rat
WILSON, C. A, HERDON, H. J, BAILEY, L. C, CLAYTON, R. N
Published in Journal of endocrinology (01.03.1986)
Published in Journal of endocrinology (01.03.1986)
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Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols
CHAN, W. N, EVANS, J. M, HADLEY, M. S, HERDON, H. J, MORGAN, H. K. A, THOMPSON, M, UPTON, N
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
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SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia
BENHAM, C. D, BROWN, T. H, ROTHAUL, A. L, SMITH, S. J, WOOD, N, HUNTER, A. J, COOPER, D. G, EVANS, M. L, HARRIES, M. H, HERDON, H. J, MEAKIN, J. E, MURKITT, K. L, PATEL, S. R, ROBERTS, J. C
Published in Neuropharmacology (01.11.1993)
Published in Neuropharmacology (01.11.1993)
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Probing the Molecular Mechanism of Interaction between 4- n -Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M 1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist
Langmead, Christopher J., Fry, Victoria A. H., Forbes, Ian T., Branch, Clive L., Christopoulos, Arthur, Wood, Martyn D., Herdon, Hugh J.
Published in Molecular pharmacology (01.01.2006)
Published in Molecular pharmacology (01.01.2006)
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