Characterization of efflux transporters involved in distribution and disposition of apixaban
Zhang, Donglu, He, Kan, Herbst, John J, Kolb, Janet, Shou, Wilson, Wang, Lifei, Balimane, Praveen V, Han, Yong-Hae, Gan, Jinping, Frost, Charles E, Humphreys, W Griffith
Published in Drug metabolism and disposition (01.04.2013)
Published in Drug metabolism and disposition (01.04.2013)
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Ultrafast mass spectrometry based bioanalytical method for digoxin supporting an in vitro P-glycoprotein (P-gp) inhibition screen
Wagner, Andrew D., Kolb, Janet M., Özbal, Can C., Herbst, John J., Olah, Timothy V., Weller, Harold N., Zvyaga, Tatyana A., Shou, Wilson Z.
Published in Rapid communications in mass spectrometry (15.05.2011)
Published in Rapid communications in mass spectrometry (15.05.2011)
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Discovery, Synthesis, and Molecular Pharmacology of Selective Positive Allosteric Modulators of the δ‑Opioid Receptor
Burford, Neil T, Livingston, Kathryn E, Canals, Meritxell, Ryan, Molly R, Budenholzer, Lauren M. L, Han, Ying, Shang, Yi, Herbst, John J, O’Connell, Jonathan, Banks, Martyn, Zhang, Litao, Filizola, Marta, Bassoni, Daniel L, Wehrman, Tom S, Christopoulos, Arthur, Traynor, John R, Gerritz, Samuel W, Alt, Andrew
Published in Journal of medicinal chemistry (28.05.2015)
Published in Journal of medicinal chemistry (28.05.2015)
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Azepino-indazoles as calcitonin gene-related peptide (CGRP) receptor antagonists
Mercer, Stephen E., Chaturvedula, Prasad V., Conway, Charles M., Cook, Deborah A., Davis, Carl D., Pin, Sokhom S., Macci, Robert, Schartman, Richard, Signor, Laura J., Widmann, Kimberly A., Whiterock, Valerie J., Chen, Ping, Xu, Cen, Herbst, John J., Kostich, Walter A., Thalody, George, Macor, John E., Dubowchik, Gene M.
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
Published in Bioorganic & medicinal chemistry letters (01.01.2021)
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Journal Article
Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines
Civiello, Rita L., Han, Xiaojun, Beno, Brett R., Chaturvedula, Prasad V., Herbst, John J., Xu, Cen, Conway, Charles M., Macor, John E., Dubowchik, Gene M.
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
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Journal Article
Fluoresceinated FKBP12 ligands for a high-throughput fluorescence polarization assay
DUBOWCHIK, G. M, DITTA, J. L, HERBST, J. J, BOLLINI, S, VINITSKY, A
Published in Bioorganic & medicinal chemistry letters (20.03.2000)
Published in Bioorganic & medicinal chemistry letters (20.03.2000)
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Journal Article
Labware additives identified to be selective monoamine oxidase-B inhibitors
Stewart, Jeremy, Drexler, Dieter M, Leet, John E, McNaney, Colleen A, Herbst, John J
Published in Journal of biomolecular screening (01.12.2014)
Published in Journal of biomolecular screening (01.12.2014)
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Journal Article
Extraction, Identification, and Functional Characterization of a Bioactive Substance From Automated Compound-Handling Plastic Tips
Watson, John, Greenough, Emily B., Leet, John E., Ford, Michael J., Drexler, Dieter M., Belcastro, James V., Herbst, John J., Chatterjee, Moneesh, Banks, Martyn
Published in Journal of biomolecular screening (01.06.2009)
Published in Journal of biomolecular screening (01.06.2009)
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Journal Article
Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin
Shi, Shuhao, Zhu, Shirong, Gerritz, Samuel W., Esposito, Kim, Padmanabha, Ramesh, Li, Wenying, Herbst, John J., Wong, Henry, Shu, Yue Zhong, Lam, Kin S., Sofia, Michael J.
Published in Bioorganic & medicinal chemistry letters (15.09.2005)
Published in Bioorganic & medicinal chemistry letters (15.09.2005)
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Journal Article
Potent Activation of Phosphatidylinositol 3'-Kinase by Simple Phosphotyrosine Peptides Derived from Insulin Receptor Substrate 1 Containing Two YMXM Motifs for binding SH2 Domains
Herbst, John J, Andrews, Glenn, Contillo, Leonard, Lamphere, Lou, Gardner, Joseph, Lienhard, Gustav E, Gibbs, E. Michael
Published in Biochemistry (Easton) (01.08.1994)
Published in Biochemistry (Easton) (01.08.1994)
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Journal Article
Effect of the Activation of Phosphatidylinositol 3-Kinase by a Thiophosphotyrosine Peptide on Glucose Transport in 3T3-L1 Adipocytes (∗)
Herbst, John J., Andrews, Glenn C., Contillo, Leonard G., Singleton, David H., Genereux, Paul E., Gibbs, E. Michael, Lienhard, Gustav E.
Published in The Journal of biological chemistry (27.10.1995)
Published in The Journal of biological chemistry (27.10.1995)
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The antihyperglycemic agent englitazone prevents the defect in glucose transport in rats fed a high-fat diet
STEVENSON, R. W, MCPHERSON, R. K, PERSSON, L. M, GENEREUX, P. E, SWICK, A. G, SPITZER, J, HERBST, J. J, ANDREWS, K. M, KREUTTER, D. K, GIBBS, E. M
Published in Diabetes (New York, N.Y.) (1996)
Published in Diabetes (New York, N.Y.) (1996)
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Journal Article
Evidence for Classical Cholinergic Toxicity Associated with Selective Activation of M1 Muscarinic Receptors
Alt, Andrew, Pendri, Annapurna, Bertekap, Jr, Robert L, Li, Guo, Benitex, Yulia, Nophsker, Michelle, Rockwell, Kristin L, Burford, Neil T, Sum, Chi Shing, Chen, Jing, Herbst, John J, Ferrante, Meredith, Hendricson, Adam, Cvijic, Mary Ellen, Westphal, Ryan S, O'Connell, Jonathan, Banks, Martyn, Zhang, Litao, Gentles, Robert G, Jenkins, Susan, Loy, James, Macor, John E
Published in The Journal of pharmacology and experimental therapeutics (01.02.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2016)
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