Characterization of gastrointestinal transit and luminal conditions in pigs using a telemetric motility capsule
Henze, Laura J., Koehl, Niklas J., Bennett-Lenane, Harriet, Holm, René, Grimm, Michael, Schneider, Felix, Weitschies, Werner, Koziolek, Mirko, Griffin, Brendan T.
Published in European journal of pharmaceutical sciences (01.01.2021)
Published in European journal of pharmaceutical sciences (01.01.2021)
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Journal Article
The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review
Henze, Laura J, Koehl, Niklas J, O'Shea, Joseph P, Kostewicz, Edmund S, Holm, René, Griffin, Brendan T
Published in Journal of pharmacy and pharmacology (01.04.2019)
Published in Journal of pharmacy and pharmacology (01.04.2019)
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Journal Article
Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions
Poetsch, Florian, Henze, Laura A, Estepa, Misael, Moser, Barbara, Pieske, Burkert, Lang, Florian, Eckardt, Kai-Uwe, Alesutan, Ioana, Voelkl, Jakob
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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Journal Article
Lipophilic Salts and Lipid-Based Formulations for Bridging the Food Effect Gap of Venetoclax
Koehl, Niklas J., Henze, Laura J., Holm, René, Kuentz, Martin, Keating, John J., De Vijlder, Thomas, Marx, Andreas, Griffin, Brendan T.
Published in Journal of pharmaceutical sciences (01.01.2022)
Published in Journal of pharmaceutical sciences (01.01.2022)
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Journal Article
Augmentative effects of leukemia inhibitory factor reveal a critical role for TYK2 signaling in vascular calcification
Alesutan, Ioana, Razazian, Mehdi, Luong, Trang T.D., Estepa, Misael, Pitigala, Lakmi, Henze, Laura A., Obereigner, Jakob, Mitter, Gregor, Zickler, Daniel, Schuchardt, Mirjam, Deisl, Christine, Makridakis, Manousos, Gollmann-Tepeköylü, Can, Pasch, Andreas, Cejka, Daniel, Suessner, Susanne, Antlanger, Marlies, Bielesz, Bernhard, Müller, Mathias, Vlahou, Antonia, Holfeld, Johannes, Eckardt, Kai-Uwe, Voelkl, Jakob
Published in Kidney international (01.10.2024)
Published in Kidney international (01.10.2024)
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Journal Article
In Silico, In Vitro, and In Vivo Evaluation of Precipitation Inhibitors in Supersaturated Lipid-Based Formulations of Venetoclax
Koehl, Niklas J, Henze, Laura J, Bennett-Lenane, Harriet, Faisal, Waleed, Price, Daniel J, Holm, René, Kuentz, Martin, Griffin, Brendan T
Published in Molecular pharmaceutics (07.06.2021)
Published in Molecular pharmaceutics (07.06.2021)
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Journal Article
Development and evaluation of a biorelevant medium simulating porcine gastrointestinal fluids
Henze, Laura J., Koehl, Niklas J., Jansen, Regina, Holm, René, Vertzoni, Maria, Whitfield, Phil D., Griffin, Brendan T.
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2020)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2020)
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Journal Article
Combining species specific in vitro & in silico models to predict in vivo food effect in a preclinical stage – case study of Venetoclax
Henze, Laura J., Koehl, Niklas J., O'Shea, Joseph P., Holm, René, Vertzoni, Maria, Griffin, Brendan T.
Published in European journal of pharmaceutical sciences (01.07.2021)
Published in European journal of pharmaceutical sciences (01.07.2021)
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Journal Article
Exploring gastric emptying rate in minipigs: Effect of food type and pre-dosing of metoclopramide
Henze, Laura J., Griffin, Brendan T., Christiansen, Martin, Bundgaard, Christoffer, Langguth, Peter, Holm, René
Published in European journal of pharmaceutical sciences (15.06.2018)
Published in European journal of pharmaceutical sciences (15.06.2018)
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Journal Article
Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax
Koehl, Niklas J., Henze, Laura J., Kuentz, Martin, Holm, René, Griffin, Brendan T.
Published in Pharmaceutics (18.06.2020)
Published in Pharmaceutics (18.06.2020)
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Journal Article
Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration
O'Dwyer, Patrick J, Box, Karl J, Dressman, Jennifer, Griffin, Brendan T, Henze, Laura J, Litou, Chara, Pentafragka, Christina, Statelova, Marina, Vertzoni, Maria, Reppas, Christos
Published in Journal of pharmacy and pharmacology (08.03.2021)
Published in Journal of pharmacy and pharmacology (08.03.2021)
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Journal Article
Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells
Henze, Laura A, Luong, Trang T D, Boehme, Beate, Masyout, Jaber, Schneider, Markus P, Brachs, Sebastian, Lang, Florian, Pieske, Burkert, Pasch, Andreas, Eckardt, Kai-Uwe, Voelkl, Jakob, Alesutan, Ioana
Published in Aging (Albany, NY.) (03.08.2019)
Published in Aging (Albany, NY.) (03.08.2019)
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Journal Article
Exploring porcine gastric and intestinal fluids using microscopic and solubility estimates: Impact of placebo self-emulsifying drug delivery system administration to inform bio-predictive in vitro tools
Bennett-Lenane, Harriet, Jørgensen, Jacob R., Koehl, Niklas J., Henze, Laura J., O'Shea, Joseph P., Müllertz, Anette, Griffin, Brendan T.
Published in European journal of pharmaceutical sciences (01.06.2021)
Published in European journal of pharmaceutical sciences (01.06.2021)
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Journal Article
Periostin Augments Vascular Smooth Muscle Cell Calcification via β-Catenin Signaling
Alesutan, Ioana, Henze, Laura A, Boehme, Beate, Luong, Trang T. D, Zickler, Daniel, Pieske, Burkert, Eckardt, Kai-Uwe, Pasch, Andreas, Voelkl, Jakob
Published in Biomolecules (Basel, Switzerland) (01.08.2022)
Published in Biomolecules (Basel, Switzerland) (01.08.2022)
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Journal Article
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment
Chiorazzi, Michael, Martinek, Jan, Krasnick, Bradley, Zheng, Yunjiang, Robbins, Keenan J, Qu, Rihao, Kaufmann, Gabriel, Skidmore, Zachary, Juric, Melani, Henze, Laura A, Brösecke, Frederic, Adonyi, Adam, Zhao, Jun, Shan, Liang, Sefik, Esen, Mudd, Jacqueline, Bi, Ye, Goedegebuure, S Peter, Griffith, Malachi, Griffith, Obi, Oyedeji, Abimbola, Fertuzinhos, Sofia, Garcia-Milian, Rolando, Boffa, Daniel, Detterbeck, Frank, Dhanasopon, Andrew, Blasberg, Justin, Judson, Benjamin, Gettinger, Scott, Politi, Katerina, Kluger, Yuval, Palucka, Karolina, Fields, Ryan C, Flavell, Richard A
Published in Journal for immunotherapy of cancer (01.07.2023)
Published in Journal for immunotherapy of cancer (01.07.2023)
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Journal Article
Toward the establishment of a standardized pre-clinical porcine model to predict food effects – Case studies on fenofibrate and paracetamol
Henze, Laura J., Koehl, Niklas J., O'Shea, Joseph P., Holm, René, Vertzoni, Maria, Griffin, Brendan T.
Published in International journal of pharmaceutics: X (01.12.2019)
Published in International journal of pharmaceutics: X (01.12.2019)
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Journal Article
Role of Cytosolic Serine Hydroxymethyl Transferase 1 (SHMT1) in Phosphate-Induced Vascular Smooth Muscle Cell Calcification
Boehme, Beate, Schelski, Nadeshda, Makridakis, Manousos, Henze, Laura, Vlahou, Antonia, Lang, Florian, Pieske, Burkert, Alesutan, Ioana, Voelkl, Jakob
Published in Kidney & blood pressure research (01.01.2018)
Published in Kidney & blood pressure research (01.01.2018)
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Journal Article
Abstract NG11: Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment
Chiorazzi, Michael, Martinek, Jan, Krasnick, Bradley, Zheng, Yunjiang, Robbins, Keenan, Qu, Rihao, Kaufmann, Gabriel, Skidmore, Zachary, Henze, Laura, Brösecke, Frederic, Adonyi, Adam, Zhao, Jun, Shan, Liang, Sefik, Esen, Mudd, Jacqueline, Bi, Ye, Goedegebuure, S Peter, Griffith, Malachi, Griffith, Obi, Oyedeji, Abimbola, Fertuzinhos, Sofia, Garcia-Milian, Roland, Boffa, Daniel, Detterbeck, Frank, Dhanasopon, Andrew, Blasberg, Justin, Judson, Benjamin, Gettinger, Scott, Politi, Katerina, Kluger, Yuval, Palucka, A Karolina, Fields, Ryan, Flavell, Richard A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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