The reaction cycle of isopenicillin N synthase observed by X-ray diffraction
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Published in Nature (London) (14.10.1999)
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Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme
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Published in Structure (London) (10.03.2010)
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Bovine antibody-enriched whey to aid in the prevention of a relapse of Clostridium difficile-associated diarrhoea: preclinical and preliminary clinical data
van Dissel, Jaap T, de Groot, Nanda, Hensgens, Charles MH, Numan, Sandra, Kuijper, Ed J, Veldkamp, Peter, van 't Wout, Jan
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Controlling the Substrate Selectivity of Deacetoxycephalosporin/deacetylcephalosporin C Synthase
Lloyd, Matthew D., Lipscomb, Sarah J., Hewitson, Kirsty S., Hensgens, Charles M.H., Baldwin, Jack E., Schofield, Christopher J.
Published in The Journal of biological chemistry (09.04.2004)
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Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase
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Published in Protein engineering, design and selection (01.05.2004)
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X-ray analysis of two antibiotic-synthesizing bacterial ester hydrolases: preliminary results
Barends, Thomas R. M., Hensgens, Charles M. H., Polderman-Tijmes, Jolanda J., Jekel, Peter A., De Vries, Erik, Janssen, Dick B., Dijkstra, Bauke W.
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2003)
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2003)
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Purification, crystallization and preliminary X-ray diffraction of Cys103Ala acyl coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum
Hensgens, Charles M. H., Kroezinga, Els A., Van Montfort, Bart A., Van Der Laan, Jan-Metske, Sutherland, John D., Dijkstra, Bauke W.
Published in Acta crystallographica. Section D, Biological crystallography. (01.04.2002)
Published in Acta crystallographica. Section D, Biological crystallography. (01.04.2002)
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Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation
ROACH, P. L, CLIFTON, I. J, HENSGENS, C. M. H, SHIBATA, N, SCHOFIELD, C. J, HAJDU, J, BALDWIN, J. E
Published in Nature (London) (19.06.1997)
Published in Nature (London) (19.06.1997)
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The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases
Barends, Thomas R M, Polderman-Tijmes, Jolanda J, Jekel, Peter A, Hensgens, Charles M H, de Vries, Erik J, Janssen, Dick B, Dijkstra, Bauke W
Published in The Journal of biological chemistry (20.06.2003)
Published in The Journal of biological chemistry (20.06.2003)
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The Sequence and Crystal Structure of the α-Amino Acid Ester Hydrolase from Xanthomonas citri Define a New Family of β-Lactam Antibiotic Acylases
Thomas R. M. Barends, Jolanda J. Polderman-Tijmes, Peter A. Jekel, Charles M. H. Hensgens, Erik J. de Vries, Dick B. Janssen, Bauke W. Dijkstra
Published in The Journal of biological chemistry (20.06.2003)
Published in The Journal of biological chemistry (20.06.2003)
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An approach to prevent aggregation during the purification and crystallization of wild type acyl coenzyme A: Isopenicillin N acyltransferase from Penicillium chrysogenum
Yoshida, Hiromi, Hensgens, Charles M.H., van der Laan, Jan Metske, Sutherland, John D., Hart, Darren J., Dijkstra, Bauke W.
Published in Protein expression and purification (01.05.2005)
Published in Protein expression and purification (01.05.2005)
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