Gastrointestinal behavior of nano- and microsized fenofibrate: In vivo evaluation in man and in vitro simulation by assessment of the permeation potential
Hens, Bart, Brouwers, Joachim, Corsetti, Maura, Augustijns, Patrick
Published in European journal of pharmaceutical sciences (18.09.2015)
Published in European journal of pharmaceutical sciences (18.09.2015)
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Journal Article
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2–infected hamsters, whereas hydroxychloroquine lacks activity
Kaptein, Suzanne J. F., Jacobs, Sofie, Langendries, Lana, Seldeslachts, Laura, ter Horst, Sebastiaan, Liesenborghs, Laurens, Hens, Bart, Vergote, Valentijn, Heylen, Elisabeth, Barthelemy, Karine, Maas, Elke, De Keyzer, Carolien, Bervoets, Lindsey, Rymenants, Jasper, Van Buyten, Tina, Zhang, Xin, Abdelnabi, Rana, Pang, Juanita, Williams, Rachel, Thibaut, Hendrik Jan, Dallmeier, Kai, Boudewijns, Robbert, Wouters, Jens, Augustijns, Patrick, Verougstraete, Nick, Cawthorne, Christopher, Breuer, Judith, Solas, Caroline, Weynand, Birgit, Annaert, Pieter, Spriet, Isabel, Velde, Greetje Vande, Neyts, Johan, Rocha-Pereira, Joana, Delang, Leen
Published in Proceedings of the National Academy of Sciences - PNAS (27.10.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (27.10.2020)
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The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group
Koziolek, Mirko, Alcaro, Stefano, Augustijns, Patrick, Basit, Abdul W., Grimm, Michael, Hens, Bart, Hoad, Caroline L., Jedamzik, Philipp, Madla, Christine M., Maliepaard, Marc, Marciani, Luca, Maruca, Annalisa, Parrott, Neil, Pávek, Petr, Porter, Christopher J.H., Reppas, Christos, van Riet-Nales, Diana, Rubbens, Jari, Statelova, Marina, Trevaskis, Natalie L., Valentová, Kateřina, Vertzoni, Maria, Čepo, Dubravka Vitali, Corsetti, Maura
Published in European journal of pharmaceutical sciences (15.06.2019)
Published in European journal of pharmaceutical sciences (15.06.2019)
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Journal Article
Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs
Hens, Bart, Tsume, Yasuhiro, Bermejo, Marival, Paixao, Paulo, Koenigsknecht, Mark J, Baker, Jason R, Hasler, William L, Lionberger, Robert, Fan, Jianghong, Dickens, Joseph, Shedden, Kerby, Wen, Bo, Wysocki, Jeffrey, Loebenberg, Raimar, Lee, Allen, Frances, Ann, Amidon, Greg, Yu, Alex, Benninghoff, Gail, Salehi, Niloufar, Talattof, Arjang, Sun, Duxin, Amidon, Gordon L
Published in Molecular pharmaceutics (04.12.2017)
Published in Molecular pharmaceutics (04.12.2017)
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A Mechanistic Physiologically-Based Biopharmaceutics Modeling (PBBM) Approach to Assess the In Vivo Performance of an Orally Administered Drug Product: From IVIVC to IVIVP
Bermejo, Marival, Hens, Bart, Dickens, Joseph, Mudie, Deanna, Paixão, Paulo, Tsume, Yasuhiro, Shedden, Kerby, Amidon, Gordon L
Published in Pharmaceutics (17.01.2020)
Published in Pharmaceutics (17.01.2020)
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Journal Article
Haematoma evacuation in cerebellar intracerebral haemorrhage: systematic review
Singh, Sanjula Dhillon, Brouwers, Hens Bart, Senff, Jasper Rudolf, Pasi, Marco, Goldstein, Joshua, Viswanathan, Anand, Klijn, Catharina J M, Rinkel, Gabriël Johannes Engelmundus
Published in Journal of neurology, neurosurgery and psychiatry (01.01.2020)
Published in Journal of neurology, neurosurgery and psychiatry (01.01.2020)
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Journal Article
Bile Salt Micelles and Phospholipid Vesicles Present in Simulated and Human Intestinal Fluids: Structural Analysis by Flow Field–Flow Fractionation/Multiangle Laser Light Scattering
Elvang, Philipp A., Hinna, Askell H., Brouwers, Joachim, Hens, Bart, Augustijns, Patrick, Brandl, Martin
Published in Journal of pharmaceutical sciences (01.09.2016)
Published in Journal of pharmaceutical sciences (01.09.2016)
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Journal Article
Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate–CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical Significance
Al-Gousous, Jozef, Sun, Kathy X, McNamara, Daniel P, Hens, Bart, Salehi, Niloufar, Langguth, Peter, Bermejo, Marival, Amidon, Gregory E, Amidon, Gordon L
Published in Molecular pharmaceutics (05.11.2018)
Published in Molecular pharmaceutics (05.11.2018)
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Journal Article
Measuring the Impact of Gastrointestinal Variables on the Systemic Outcome of Two Suspensions of Posaconazole by a PBPK Model
Hens, Bart, Talattof, Arjang, Paixão, Paulo, Bermejo, Marival, Tsume, Yasuhiro, Löbenberg, Raimar, Amidon, Gordon L.
Published in The AAPS journal (29.03.2018)
Published in The AAPS journal (29.03.2018)
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Journal Article
Gastric emptying and intestinal appearance of nonabsorbable drugs phenol red and paromomycin in human subjects: A multi-compartment stomach approach
Paixão, Paulo, Bermejo, Marival, Hens, Bart, Tsume, Yasuhiro, Dickens, Joseph, Shedden, Kerby, Salehi, Niloufar, Koenigsknecht, Mark J., Baker, Jason R., Hasler, William L., Lionberger, Robert, Fan, Jianghong, Wysocki, Jeffrey, Wen, Bo, Lee, Allen, Frances, Ann, Amidon, Gregory E., Yu, Alex, Benninghoff, Gail, Löbenberg, Raimar, Talattof, Arjang, Sun, Duxin, Amidon, Gordon L.
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2018)
Published in European journal of pharmaceutics and biopharmaceutics (01.08.2018)
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Measurement of fasted state gastric antral motility before and after a standard bioavailability and bioequivalence 240 mL drink of water: Validation of MRI method against concomitant perfused manometry in healthy participants
Heissam, Khaled, Abrehart, Nichola, Hoad, Caroline L, Wright, Jeff, Menys, Alex, Murray, Kathryn, Glover, Paul M, Hebbard, Geoffrey, Gowland, Penny A, Baker, Jason, Hasler, William L, Spiller, Robin C, Corsetti, Maura, Brasseur, James G, Hens, Bart, Shedden, Kerby, Dickens, Joseph, Mudie, Deanna M, Amidon, Greg E, Amidon, Gordon L, Marciani, Luca
Published in PloS one (11.11.2020)
Published in PloS one (11.11.2020)
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Journal Article
Application of the Gastrointestinal Simulator (GIS) Coupled with In Silico Modeling to Measure the Impact of Coca-Cola® on the Luminal and Systemic Behavior of Loratadine (BCS Class 2b)
Hens, Bart, Bermejo, Marival, Augustijns, Patrick, Cristofoletti, Rodrigo, Amidon, Gregory, Amidon, Gordon
Published in Pharmaceutics (18.06.2020)
Published in Pharmaceutics (18.06.2020)
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Journal Article
Biopredictive in vitro testing methods to assess intestinal drug absorption from supersaturating dosage forms
Hens, Bart, Kataoka, Makoto, Ueda, Keisuke, Gao, Ping, Tsume, Yasuhiro, Augustijns, Patrick, Kawakami, Kohsaku, Yamashita, Shinji
Published in Journal of drug delivery science and technology (01.04.2020)
Published in Journal of drug delivery science and technology (01.04.2020)
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Journal Article
An In Vivo Predictive Dissolution Methodology (iPD Methodology) with a BCS Class IIb Drug Can Predict the In Vivo Bioequivalence Results: Etoricoxib Products
Gonzalez-Alvarez, Isabel, Bermejo, Marival, Tsume, Yasuhiro, Ruiz-Picazo, Alejandro, Gonzalez-Alvarez, Marta, Hens, Bart, Garcia-Arieta, Alfredo, Amidon, Greg E, Amidon, Gordon L
Published in Pharmaceutics (07.04.2021)
Published in Pharmaceutics (07.04.2021)
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Journal Article
Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses
Bermejo, Marival, Kuminek, Gislaine, Al-Gousous, Jozef, Ruiz-Picazo, Alejandro, Tsume, Yasuhiro, Garcia-Arieta, Alfredo, González-Alvarez, Isabel, Hens, Bart, Amidon, Gregory E, Rodriguez-Hornedo, Nair, Amidon, Gordon L, Mudie, Deanna
Published in Pharmaceutics (15.03.2019)
Published in Pharmaceutics (15.03.2019)
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