Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria
Brodsky, Robert A., Young, Neal S., Antonioli, Elisabetta, Risitano, Antonio M., Schrezenmeier, Hubert, Schubert, Jörg, Gaya, Anna, Coyle, Luke, de Castro, Carlos, Fu, Chieh-Lin, Maciejewski, Jaroslaw P., Bessler, Monica, Kroon, Henk-André, Rother, Russell P., Hillmen, Peter
Published in Blood (15.02.2008)
Published in Blood (15.02.2008)
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J08 A phase 2 open label study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous ANX005 in patients with, or at risk of, manifest Huntington’s disease (HD)
Kumar, Rajeev, Claassen, Daniel O, Mongan, Ann, Hoehn, Benjamin, Lin, Ping, Cahir-Mcfarland, Ellen, Taylor, Lori, Chandra, Priya, Yednock, Ted, Kroon, Henk-André
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
Published in Journal of neurology, neurosurgery and psychiatry (12.09.2022)
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Safety, Tolerability, and Clinical Pharmacology of ANX009, an Inhibitory Antibody Fab Fragment Against C1q, Administered Subcutaneously to Healthy Volunteers
Grover, Anita, Teigler, Jeffrey, Radomile, Emily, Rose, Shawn, Yednock, Ted, Keswani, Sanjay, Kroon, Henk-Andre
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Classical Complement Activation in Lupus Nephritis Correlates with Disease Biomarkers: Results from Two Observational Studies: SA-PO931
Chang, Edmund, Low, Julian, Yousefpour, Noosha, Bao, Min, Osterloh, Jeannette, Chang, Qing, Artis, Dean R., Kroon, Henk-Andre, Andrews-Zwilling, Yaisa, Dall'Era, Maria, Yednock, Ted, Mongan, Ann
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Results of Single-Arm, Phase 1b Study of Anti-C1q Treatment (ANX009) Show that the Classical Pathway Is a Key Driver of Complement Activation and Consumption in Patients with Active Lupus Nephritis: SA-PO878
Bao, Min, Lichauco, Juan, Chen, Hsiang, Gomez, Harold, Tee, Michael L., Arroyo, Caroline, Lan, Joung-Liang, Fang, Yao-Fan, Chang, Edmund, Yousefpour, Noosha, Low, Julian, Chang, Qing, Osterloh, Jeannette, Manser, Paul, Mongan, Ann, Yednock, Ted, Artis, Dean R., Kroon, Henk-Andre, Andrews-Zwilling, Yaisa, Dall'Era, Maria
Published in Journal of the American Society of Nephrology (01.11.2023)
Published in Journal of the American Society of Nephrology (01.11.2023)
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Journal Article
Disease-Related Symptoms Reported across a Broad Population of Patients with Paroxysmal Nocturnal Hemoglobinuria
Meyers, Gabrielle, Weitz, Ilene, Lamy, Thierry, Cahn, Jean-Yves, Kroon, Henk-André, Severino, Beth, Uranga, Maria Teresa, Alonso, Miguel Sanz, Vela, José Antonio García, Hill, Anita
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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PHASE I INDIVIDUAL DOSE TITRATION TRIAL OF THE HUMAN CORTICOTROPIN-RELEASING FACTOR (HCRF), CORTICORELIN ACETATE INJECTION (XERECEPT) IN PEDIATRIC PATIENTS WITH PERITUMORAL EDEMA OF THE BRAIN
Goldman, S., Fangusaro, J., Lulla, R., Chi, S., Manley, P., Robison, N., Kroon, H.-A., Kieran, M.
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
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COMPOSITIONS AND METHODS FOR TREATING LUPUS NEPHRITIS
YEDNOCK, Ted, KROON, Henk-Andre, ARTIS, Dean, ANDREWS-ZWILLING, Yaisa, MONGAN, Ann, CAHIR-MCFARLAND, Ellen
Year of Publication 07.11.2024
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Year of Publication 07.11.2024
Patent
Effect of the Terminal Complement Inhibitor Eculizumab on Patient Reported Outcomes in Paroxysmal Nocturnal Hemoglobinuria (PNH): Phase III Triumph Study Results
Brodsky, Robert A., Muus, Petra, Dührsen, Ulrich, Hill, Anita, Bessler, Monica, Coutre, Steven, De Paz, Raquel, Moskovits, Tibor, Nakamura, Ryotaro, Van den Neste, Eric, Zanella, Alberto, Quinn-Senger, Kerry, Kroon, Henk-Andre, Cella, David
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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Journal Article
COMPOSITIONS AND METHODS FOR TREATING LUPUS NEPHRITIS
YEDNOCK, Ted, KROON, Henk-Andre, ARTIS, Dean, ANDREWS-ZWILLING, Yaisa, MONGAN, Ann, CAHIR-MCFARLAND, Ellen
Year of Publication 16.11.2023
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Year of Publication 16.11.2023
Patent