DNA topoisomerase I and DNA gyrase as targets for TB therapy
Nagaraja, Valakunja, Godbole, Adwait A., Henderson, Sara R., Maxwell, Anthony
Published in Drug discovery today (01.03.2017)
Published in Drug discovery today (01.03.2017)
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Journal Article
Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase
Henderson, Sara R, Stevenson, Clare E M, Malone, Brandon, Zholnerovych, Yelyzaveta, Mitchenall, Lesley A, Pichowicz, Mark, McGarry, David H, Cooper, Ian R, Charrier, Cedric, Salisbury, Anne-Marie, Lawson, David M, Maxwell, Anthony
Published in Journal of antimicrobial chemotherapy (01.10.2020)
Published in Journal of antimicrobial chemotherapy (01.10.2020)
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Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa
Cotman, Andrej Emanuel, Durcik, Martina, Benedetto Tiz, Davide, Fulgheri, Federica, Secci, Daniela, Sterle, Maša, Možina, Štefan, Skok, Žiga, Zidar, Nace, Zega, Anamarija, Ilaš, Janez, Peterlin Mašič, Lucija, Tomašič, Tihomir, Hughes, Diarmaid, Huseby, Douglas L., Cao, Sha, Garoff, Linnéa, Berruga Fernández, Talía, Giachou, Paraskevi, Crone, Lisa, Simoff, Ivailo, Svensson, Richard, Birnir, Bryndis, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., de la Cruz, Mercedes, Glinghammar, Björn, Lenhammar, Lena, Henderson, Sara R., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel
Published in Journal of medicinal chemistry (26.01.2023)
Published in Journal of medicinal chemistry (26.01.2023)
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The crystal structure of mycobacterial epoxide hydrolase A
Schulz, Eike C, Henderson, Sara R, Illarionov, Boris, Crosskey, Thomas, Southall, Stacey M, Krichel, Boris, Uetrecht, Charlotte, Fischer, Markus, Wilmanns, Matthias
Published in Scientific reports (06.10.2020)
Published in Scientific reports (06.10.2020)
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Exploring the interaction of N-(benzothiazol-2-yl)pyrrolamide DNA gyrase inhibitors with the GyrB ATP-binding site lipophilic floor: A medicinal chemistry and QTAIM study
Zidar, Nace, Emanuel Cotman, Andrej, Sinnige, Wessel, Benek, Ondrej, Barančokova, Michaela, Zega, Anamarija, Peterlin Mašič, Lucija, Tomašič, Tihomir, Ilaš, Janez, Henderson, Sara R., Mundy, Julia E.A., Maxwell, Anthony, Stevenson, Clare E.M., Lawson, David M., Jan Sterk, Geert, Tosso, Rodrigo, Gutierrez, Lucas, Enriz, Ricardo D., Kikelj, Danijel
Published in Bioorganic & medicinal chemistry (15.07.2024)
Published in Bioorganic & medicinal chemistry (15.07.2024)
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Journal Article
OXA-66 structure and oligomerisation of OXAAb enzymes
Takebayashi, Yuiko, Henderson, Sara R., Chirgadze, Dimitri Y., Warburton, Philip J., Evans, Benjamin A.
Published in Access microbiology (28.10.2022)
Published in Access microbiology (28.10.2022)
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Journal Article
Exploring the 5‑Substituted 2‑Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens
Sterle, Maša, Durcik, Martina, Stevenson, Clare E. M., Henderson, Sara R., Szili, Petra Eva, Czikkely, Marton, Lawson, David M., Maxwell, Anthony, Cahard, Dominique, Kikelj, Danijel, Zidar, Nace, Pal, Csaba, Mašič, Lucija Peterlin, Ilaš, Janez, Tomašič, Tihomir, Cotman, Andrej Emanuel, Zega, Anamarija
Published in ACS omega (11.07.2023)
Published in ACS omega (11.07.2023)
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