Lipoprotein lipase is active as a monomer
Beigneux, Anne P., Allan, Christopher M., Sandoval, Norma P., Cho, Geoffrey W., Heizer, Patrick J., Jung, Rachel S., Stanhope, Kimber L., Havel, Peter J., Birrane, Gabriel, Meiyappan, Muthuraman, Gill, John E., Murakami, Masami, Miyashita, Kazuya, Nakajima, Katsuyuki, Ploug, Michael, Fong, Loren G., Young, Stephen G.
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2019)
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Journal Article
An absence of lamin B1 in migrating neurons causes nuclear membrane ruptures and cell death
Chen, Natalie Y., Yang, Ye, Weston, Thomas A., Belling, Jason N., Heizer, Patrick, Tu, Yiping, Kim, Paul, Edillo, Lovelyn, Jonas, Steven J., Weiss, Paul S., Fong, Loren G., Young, Stephen G.
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2019)
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Journal Article
Increased expression of LAP2β eliminates nuclear membrane ruptures in nuclear lamin–deficient neurons and fibroblasts
Chen, Natalie Y., Kim, Paul H., Tu, Yiping, Yang, Ye, Heizer, Patrick J., Young, Stephen G., Fong, Loren G.
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (22.06.2021)
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Journal Article
Macrophages release plasma membrane-derived particles rich in accessible cholesterol
He, Cuiwen, Hu, Xuchen, Weston, Thomas A., Jung, Rachel S., Sandhu, Jaspreet, Huang, Song, Heizer, Patrick, Kim, Jason, Ellison, Rochelle, Xu, Jiake, Kilburn, Matthew, Bensinger, Steven J., Riezman, Howard, Tontonoz, Peter, Fong, Loren G., Jiang, Haibo, Young, Stephen G.
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (04.09.2018)
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Journal Article
Release of cholesterol-rich particles from the macrophage plasma membrane during movement of filopodia and lamellipodia
Hu, Xuchen, Weston, Thomas A, He, Cuiwen, Jung, Rachel S, Heizer, Patrick J, Young, Brian D, Tu, Yiping, Tontonoz, Peter, Wohlschlegel, James A, Jiang, Haibo, Young, Stephen G, Fong, Loren G
Published in eLife (05.09.2019)
Published in eLife (05.09.2019)
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Journal Article
Deficiency in ZMPSTE24 and resulting farnesyl–prelamin A accumulation only modestly affect mouse adipose tissue stores[S]
Heizer, Patrick J., Yang, Ye, Tu, Yiping, Kim, Paul H., Chen, Natalie Y., Hu, Yan, Yoshinaga, Yuko, de Jong, Pieter J., Vergnes, Laurent, Morales, Jazmin E., Li, Robert L., Jackson, Nicholas, Reue, Karen, Young, Stephen G., Fong, Loren G.
Published in Journal of lipid research (01.03.2020)
Published in Journal of lipid research (01.03.2020)
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Journal Article
Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding
Allan, Christopher M., Jung, Cris J., Larsson, Mikael, Heizer, Patrick J., Tu, Yiping, Sandoval, Norma P., Dang, Tiffany Ly P., Jung, Rachel S., Beigneux, Anne P., de Jong, Pieter J., Fong, Loren G., Young, Stephen G.
Published in Journal of lipid research (01.07.2017)
Published in Journal of lipid research (01.07.2017)
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Journal Article
Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure
Larsson, Mikael, Allan, Christopher M., Heizer, Patrick J., Tu, Yiping, Sandoval, Norma P., Jung, Rachel S., Walzem, Rosemary L., Beigneux, Anne P., Young, Stephen G., Fong, Loren G.
Published in Journal of lipid research (01.04.2018)
Published in Journal of lipid research (01.04.2018)
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Journal Article
Nuclear membrane ruptures underlie the vascular pathology in a mouse model of Hutchinson-Gilford progeria syndrome
Kim, Paul H, Chen, Natalie Y, Heizer, Patrick J, Tu, Yiping, Weston, Thomas A, Fong, Jared L-C, Gill, Navjot Kaur, Rowat, Amy C, Young, Stephen G, Fong, Loren G
Published in JCI insight (23.08.2021)
Published in JCI insight (23.08.2021)
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Journal Article
A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency
Allan, Christopher M., Tran, Deanna, Tu, Yiping, Heizer, Patrick J., Young, Lorraine C., Fong, Loren G., Beigneux, Anne P., Young, Stephen G.
Published in Experimental dermatology (01.11.2017)
Published in Experimental dermatology (01.11.2017)
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Journal Article
Palmoplantar keratoderma in Slurp1/Slurp2 double-knockout mice
Allan, Christopher M., Heizer, Patrick J., Jung, Cris J., Tu, Yiping, Tran, Deanna, Young, Lorraine C., Fong, Loren G., de Jong, Pieter J., Beigneux, Anne P., Young, Stephen G.
Published in Journal of dermatological science (01.01.2018)
Published in Journal of dermatological science (01.01.2018)
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Journal Article
An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner[S]
Allan, Christopher M., Heizer, Patrick J., Tu, Yiping, Sandoval, Norma P., Jung, Rachel S., Morales, Jazmin E., Sajti, Eniko, Troutman, Ty D., Saunders, Thomas L., Cusanovich, Darren A., Beigneux, Anne P., Romanoski, Casey E., Fong, Loren G., Young, Stephen G.
Published in Journal of lipid research (01.04.2019)
Published in Journal of lipid research (01.04.2019)
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Journal Article
GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients
Hu, Xuchen, Matsumoto, Ken, Jung, Rachel S, Weston, Thomas A, Heizer, Patrick J, He, Cuiwen, Sandoval, Norma P, Allan, Christopher M, Tu, Yiping, Vinters, Harry V, Liau, Linda M, Ellison, Rochelle M, Morales, Jazmin E, Baufeld, Lynn J, Bayley, Nicholas A, He, Liqun, Betsholtz, Christer, Beigneux, Anne P, Nathanson, David A, Gerhardt, Holger, Young, Stephen G, Fong, Loren G, Jiang, Haibo
Published in eLife (06.06.2019)
Published in eLife (06.06.2019)
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Journal Article
Cultured macrophages transfer surplus cholesterol into adjacent cells in the absence of serum or high-density lipoproteins
He, Cuiwen, Jiang, Haibo, Song, Wenxin, Riezman, Howard, Tontonoz, Peter, Weston, Thomas A., Guagliardo, Paul, Kim, Paul H., Jung, Rachel, Heizer, Patrick, Fong, Loren G., Young, Stephen G.
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2020)
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Journal Article
NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes
He, Cuiwen, Weston, Thomas A., Jung, Rachel S., Heizer, Patrick, Larsson, Mikael, Hu, Xuchen, Allan, Christopher M., Tontonoz, Peter, Reue, Karen, Beigneux, Anne P., Ploug, Michael, Holme, Andrea, Kilburn, Matthew, Guagliardo, Paul, Ford, David A., Fong, Loren G., Young, Stephen G., Jiang, Haibo
Published in Cell metabolism (01.05.2018)
Published in Cell metabolism (01.05.2018)
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Journal Article
Disrupting the LINC complex in smooth muscle cells reduces aortic disease in a mouse model of Hutchinson-Gilford progeria syndrome
Kim, Paul H, Luu, Jennings, Heizer, Patrick, Tu, Yiping, Weston, Thomas A, Chen, Natalie, Lim, Christopher, Li, Robert L, Lin, Po-Yu, Dunn, James C Y, Hodzic, Didier, Young, Stephen G, Fong, Loren G
Published in Science translational medicine (26.09.2018)
Published in Science translational medicine (26.09.2018)
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Journal Article
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures
Song, Wenxin, Yang, Ye, Heizer, Patrick, Tu, Yiping, Weston, Thomas A, Kim, Joonyoung R, Munguia, Priscilla, Jung, Hyesoo, Fong, Jared L-C, Tran, Caitlyn, Ploug, Michael, Beigneux, Anne P, Young, Stephen G, Fong, Loren G
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (21.02.2023)
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Journal Article
NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes
He, Cuiwen, Hu, Xuchen, Weston, Thomas A., Jung, Rachel S., Heizer, Patrick, Tu, Yiping, Ellison, Rochelle, Matsumoto, Ken, Gerhardt, Holger, Tontonoz, Peter, Fong, Loren G., Young, Stephen G., Jiang, Haibo
Published in Biochemical and biophysical research communications (12.10.2018)
Published in Biochemical and biophysical research communications (12.10.2018)
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Journal Article
The Accumulation of Progerin Underlies the Loss of Aortic Smooth Muscle Cells in Hutchinson-Gilford Progeria Syndrome
Kim, Paul H, Kim, Joonyoung R, Heizer, Patrick J, Jung, Hyesoo, Tu, Yiping, Presnell, Ashley, Scheithauer, Julia, Yu, Rachel G, Young, Stephen G, Fong, Loren G
Published in bioRxiv (03.11.2024)
Published in bioRxiv (03.11.2024)
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