Thrombospondin-4, tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14: novel extracellular matrix modulating factors in cardiac remodelling
Mustonen, Erja, Ruskoaho, Heikki, Rysä, Jaana
Published in Annals of medicine (Helsinki) (01.12.2012)
Published in Annals of medicine (Helsinki) (01.12.2012)
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Journal Article
Transcription factor PEX1 modulates extracellular matrix turnover through regulation of MMP-9 expression
Jurado Acosta, Alicia, Rysä, Jaana, Szabo, Zoltan, Moilanen, Anne-Mari, Komati, Hiba, Nemer, Mona, Ruskoaho, Heikki
Published in Cell and tissue research (01.02.2017)
Published in Cell and tissue research (01.02.2017)
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Journal Article
GATA-4 is an angiogenic survival factor of the infarcted heart
Rysä, Jaana, Tenhunen, Olli, Serpi, Raisa, Soini, Ylermi, Nemer, Mona, Leskinen, Hanna, Ruskoaho, Heikki
Published in Circulation. Heart failure (01.05.2010)
Published in Circulation. Heart failure (01.05.2010)
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Stem cells are the most sensitive screening tool to identify toxicity of GATA4- targeted small-molecule compounds
Karhu, Tuuli, Valimaki, Mika, Jumppanen, Mikael, Pohjolainen, Lotta, Leigh, Robert, Foldes, Gabor, Gennas, Gustav Boije Af, Yli-Kauhaluoma, Jari, Ruskoaho, Heikki, Talman, Virpi
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Discovery of Small Molecules Targeting the Synergy of Cardiac Transcription Factors GATA4 and NKX2-5
Ruskoaho, Heikki J, Aro, Jani, Serpi, Raisa, Pohjolainen, Lotta, Talman, Virpi, Poso, Antti, Rysa, Jaana, Kinnunen, Sini, Tolli, Marja, Valimaki, Mika
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Journal Article
Stem cells are the most sensitive screening tool to identify toxicity of GATA4-targeted novel small-molecule compounds
Karhu, S. Tuuli, Välimäki, Mika J., Jumppanen, Mikael, Kinnunen, Sini M., Pohjolainen, Lotta, Leigh, Robert S., Auno, Samuli, Földes, Gábor, Boije af Gennäs, Gustav, Yli-Kauhaluoma, Jari, Ruskoaho, Heikki, Talman, Virpi
Published in Archives of toxicology (01.09.2018)
Published in Archives of toxicology (01.09.2018)
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Increased thrombospondin-2 in human fibrosclerotic and stenotic aortic valves
Pohjolainen, Virva, Mustonen, Erja, Taskinen, Panu, Näpänkangas, Juha, Leskinen, Hanna, Ohukainen, Pauli, Peltonen, Tuomas, Aro, Jani, Juvonen, Tatu, Satta, Jari, Ruskoaho, Heikki, Rysä, Jaana
Published in Atherosclerosis (01.01.2012)
Published in Atherosclerosis (01.01.2012)
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Journal Article
Neuronostatin, a Novel Peptide Encoded by Somatostatin Gene, Regulates Cardiac Contractile Function and Cardiomyocyte Survival
Vainio, Laura, Perjes, Abel, Ryti, Niilo, Magga, Johanna, Alakoski, Tarja, Serpi, Raisa, Kaikkonen, Leena, Piuhola, Jarkko, Szokodi, Istvan, Ruskoaho, Heikki, Kerkelä, Risto
Published in The Journal of biological chemistry (10.02.2012)
Published in The Journal of biological chemistry (10.02.2012)
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Identification of Cell Cycle Regulatory and Inflammatory Genes As Predominant Targets of p38 Mitogen-Activated Protein Kinase in the Heart
Tenhunen, Olli, Rysä, Jaana, Ilves, Mika, Soini, Ylermi, Ruskoaho, Heikki, Leskinen, Hanna
Published in Circulation research (01.09.2006)
Published in Circulation research (01.09.2006)
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Journal Article
Neoplastic extracellular matrix environment promotes cancer invasion in vitro
Sundquist, Elias, Renko, Outi, Salo, Sirpa, Magga, Johanna, Cervigne, Nilva K., Nyberg, Pia, Risteli, Juha, Sormunen, Raija, Vuolteenaho, Olli, Zandonadi, Flávia, Paes Leme, Adriana F., Coletta, Ricardo D., Ruskoaho, Heikki, Salo, Tuula
Published in Experimental cell research (10.06.2016)
Published in Experimental cell research (10.06.2016)
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Abstract 154: Transcriptomic Analysis Reveals Upregulation of The Pro-Apoptotic, Extracellular Matrix-Degrading Granzyme System in Human Aortic Valve Calcification
Ohukainen, Pauli, Peltonen, Tuomas, Näpänkangas, Juha, Taskinen, Panu, Ohtonen, Pasi, Ruskoaho, Heikki, Rysä, Jaana
Published in Circulation research (01.08.2013)
Published in Circulation research (01.08.2013)
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Molecular Heterogeneity Has a Major Impact on the Measurement of Circulating N-Terminal Fragments of A- and B-Type Natriuretic Peptides
Ala-Kopsala, Minna, Magga, Jarkko, Peuhkurinen, Keijo, Leipala, Jaana, Ruskoaho, Heikki, Leppaluoto, Juhani, Vuolteenaho, Olli
Published in Clinical chemistry (Baltimore, Md.) (01.09.2004)
Published in Clinical chemistry (Baltimore, Md.) (01.09.2004)
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Effect of vasoactive peptides in Tetrahymena: chemotactic activities of adrenomedullin, proadrenomedullin N-terminal 20 peptide (PAMP) and calcitonin gene-related peptide (CGRP)
Kőhidai, László, Tóth, Katalin, Samotik, Paul, Ranganathan, Kiran, Láng, Orsolya, Tóth, Miklós, Ruskoaho, Heikki
Published in Molecular and cellular biochemistry (01.01.2016)
Published in Molecular and cellular biochemistry (01.01.2016)
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Journal Article
Expression and Localization of Granzymes and Perforin in Human Calcific Aortic Valve Disease
Ohukainen, Pauli, Näpäkangas, Juha, Ohtonen, Pasi, Ruskoaho, Heikki, Taskinen, Panu, Peltonen, Tuomas, Rysä, Jaana
Published in The Journal of heart valve disease (01.09.2015)
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Published in The Journal of heart valve disease (01.09.2015)
Journal Article
Apelin increases cardiac contractility via protein kinase Cζ- and extracellular signal-regulated kinase-dependent mechanisms
Perjes, Abel, Skoumal, Reka, Tenhunen, Olli, Konyi, Attila, Simon, Mihaly, Horvath, Ivan G, Kerkela, Risto, Ruskoaho, Heikki, Szokodi, Istvan
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Ambulatory Pulse Pressure Predicts the Development of Left Ventricular Diastolic Dysfunction in Over 20 Years of Follow-up
Pääkkö, Tero JW, Renko, Reko J, Perkiömäki, Juha S, Kesäniemi, Y Antero, Ylitalo, Antti S, Lumme, Jarmo A, Huikuri, Heikki V, Ruskoaho, Heikki, Vuolteenaho, Olli, Ukkola, Olavi H
Published in American journal of hypertension (01.10.2017)
Published in American journal of hypertension (01.10.2017)
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