A Genetic Map of the Response to DNA Damage in Human Cells
Olivieri, Michele, Cho, Tiffany, Álvarez-Quilón, Alejandro, Li, Kejiao, Schellenberg, Matthew J., Zimmermann, Michal, Hustedt, Nicole, Rossi, Silvia Emma, Adam, Salomé, Melo, Henrique, Heijink, Anne Margriet, Sastre-Moreno, Guillermo, Moatti, Nathalie, Szilard, Rachel K., McEwan, Andrea, Ling, Alexanda K., Serrano-Benitez, Almudena, Ubhi, Tajinder, Feng, Sumin, Pawling, Judy, Delgado-Sainz, Irene, Ferguson, Michael W., Dennis, James W., Brown, Grant W., Cortés-Ledesma, Felipe, Williams, R. Scott, Martin, Alberto, Xu, Dongyi, Durocher, Daniel
Published in Cell (23.07.2020)
Published in Cell (23.07.2020)
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Journal Article
RIF1 promotes replication fork protection and efficient restart to maintain genome stability
Mukherjee, Chirantani, Tripathi, Vivek, Manolika, Eleni Maria, Heijink, Anne Margriet, Ricci, Giulia, Merzouk, Sarra, de Boer, H. Rudolf, Demmers, Jeroen, van Vugt, Marcel A. T. M., Ray Chaudhuri, Arnab
Published in Nature communications (23.07.2019)
Published in Nature communications (23.07.2019)
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Journal Article
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity
Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Published in Nature communications (09.01.2019)
Published in Nature communications (09.01.2019)
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Journal Article
Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells
Schoonen, Pepijn M., Talens, Francien, Stok, Colin, Gogola, Ewa, Heijink, Anne Margriet, Bouwman, Peter, Foijer, Floris, Tarsounas, Madalena, Blatter, Sohvi, Jonkers, Jos, Rottenberg, Sven, van Vugt, Marcel A. T. M.
Published in Nature communications (17.07.2017)
Published in Nature communications (17.07.2017)
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Journal Article
Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51
Heijink, Anne Margriet, Stok, Colin, Porubsky, David, Manolika, Eleni Maria, de Kanter, Jurrian K., Kok, Yannick P., Everts, Marieke, de Boer, H. Rudolf, Audrey, Anastasia, Bakker, Femke J., Wierenga, Elles, Tijsterman, Marcel, Guryev, Victor, Spierings, Diana C. J., Knipscheer, Puck, van Boxtel, Ruben, Ray Chaudhuri, Arnab, Lansdorp, Peter M., van Vugt, Marcel A. T. M.
Published in Nature communications (07.11.2022)
Published in Nature communications (07.11.2022)
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Journal Article
A haploid genetic screen identifies the G₁/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
Heijink, Anne Margriet, Blomen, Vincent A., Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel A. T. M.
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
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Journal Article
Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity
Heijink, Anne Margriet, Everts, Marieke, Honeywell, Megan E., Richards, Ryan, Kok, Yannick P., de Vries, Elisabeth G.E., Lee, Michael J., van Vugt, Marcel A.T.M.
Published in Cell reports (Cambridge) (27.08.2019)
Published in Cell reports (Cambridge) (27.08.2019)
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Journal Article
Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells
van den Boom, Vincent, Rozenveld-Geugien, Marjan, Bonardi, Francesco, Malanga, Donatella, van Gosliga, Djoke, Heijink, Anne Margriet, Viglietto, Giuseppe, Morrone, Giovanni, Fusetti, Fabrizia, Vellenga, Edo, Schuringa, Jan Jacob
Published in Blood (28.03.2013)
Published in Blood (28.03.2013)
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Journal Article
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
Kato, Masato, Han, Tina W., Xie, Shanhai, Shi, Kevin, Du, Xinlin, Wu, Leeju C., Mirzaei, Hamid, Goldsmith, Elizabeth J., Longgood, Jamie, Pei, Jimin, Grishin, Nick V., Frantz, Douglas E., Schneider, Jay W., Chen, She, Li, Lin, Sawaya, Michael R., Eisenberg, David, Tycko, Robert, McKnight, Steven L.
Published in Cell (11.05.2012)
Published in Cell (11.05.2012)
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Journal Article
The DNA damage response during mitosis
Heijink, Anne Margriet, Krajewska, Małgorzata, van Vugt, Marcel A T M
Published in Mutation research (01.10.2013)
Published in Mutation research (01.10.2013)
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Journal Article
TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells
van Gijn, Stephanie E., Wierenga, Elles, van den Tempel, Nathalie, Kok, Yannick P., Heijink, Anne Margriet, Spierings, Diana C. J., Foijer, Floris, van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Published in Oncogene (01.02.2019)
Published in Oncogene (01.02.2019)
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Journal Article
Abstract 1409: Analysis of 16,172 patient-derived tumor samples indicate TPX2 as being essential for survival of genomically instable cancer cells
Gijn, Stephanie E. van, Wierenga, Elles, Heijink, Anne Margriet, Fehrmann, Rudolf S., Vugt, Marcel A. van
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract LB-C23: A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
Heijink, Anne Margriet, Blomen, Vincent, Degener, Fabian, Matsushita, Felipe Yu, Foijer, Floris, Van Vugt, Marcel A.
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
A haploid genetic screen identifies the G^sub 1^/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
Heijink, Anne Margriet, Blomen, Vincent A, Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel ATM
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
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Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
Journal Article
A haploid genetic screen identifies the G 1 /S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
Heijink, Anne Margriet, Blomen, Vincent A., Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel A. T. M.
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2015)
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Journal Article
A haploid genetic screen identifies the G sub( 1)/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity
Heijink, Anne Margriet, Blomen, Vincent A, Bisteau, Xavier, Degener, Fabian, Matsushita, Felipe Yu, Kaldis, Philipp, Foijer, Floris, van Vugt, Marcel ATM
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.2015)
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Published in Proceedings of the National Academy of Sciences - PNAS (01.12.2015)
Journal Article
Sister chromatid exchanges induced by perturbed replication are formed independently of homologous recombination factors
Heijink, Anne Margriet, Stok, Colin, Porubsky, David, Manolika, Eleni M, Kok, Yannick P, Everts, Marieke, De Boer, H Rudolf, Anastasia Audrey, Wierenga, Elles, Guryev, Victor, Spierings, Diana Cj, Puck Knipscheer, Chaudhuri, Arnab Ray, Lansdorp, Peter M, Marcel Atm Van Vugt
Published in bioRxiv (18.09.2021)
Published in bioRxiv (18.09.2021)
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