Muscle Weakness in Myositis: MicroRNA‐Mediated Dystrophin Reduction in a Myositis Mouse Model and Human Muscle Biopsies
Kinder, Travis B., Heier, Christopher R., Tully, Christopher B., Van der Muelen, Jack H., Hoffman, Eric P., Nagaraju, Kanneboyina, Fiorillo, Alyson A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2020)
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Journal Article
TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy
Fiorillo, Alyson A., Heier, Christopher R., Novak, James S., Tully, Christopher B., Brown, Kristy J., Uaesoontrachoon, Kitipong, Vila, Maria C., Ngheim, Peter P., Bello, Luca, Kornegay, Joe N., Angelini, Corrado, Partridge, Terence A., Nagaraju, Kanneboyina, Hoffman, Eric P.
Published in Cell reports (Cambridge) (08.09.2015)
Published in Cell reports (Cambridge) (08.09.2015)
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Journal Article
Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs
Fiorillo, Alyson A, Heier, Christopher R, Huang, Yu-Fang, Tully, Christopher B, Punga, Tanel, Punga, Anna Rostedt
Published in Frontiers in immunology (21.02.2020)
Published in Frontiers in immunology (21.02.2020)
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Journal Article
The glucocorticoid receptor acts locally to protect dystrophic muscle and heart during disease
Oliver, Trinitee, Nguyen, Nhu Y, Tully, Christopher B, McCormack, Nikki M, Sun, Christina M, Fiorillo, Alyson A, Heier, Christopher R
Published in Disease models & mechanisms (01.05.2024)
Published in Disease models & mechanisms (01.05.2024)
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Journal Article
The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models
Gogliotti, Rocky G, Cardona, Herminio, Singh, Jasbir, Bail, Sophie, Emery, Carina, Kuntz, Nancy, Jorgensen, Michael, Durens, Madel, Xia, Bing, Barlow, Courtenay, Heier, Christopher R, Plasterer, Heather L, Jacques, Vincent, Kiledjian, Megerditch, Jarecki, Jill, Rusche, James, DiDonato, Christine J
Published in Human molecular genetics (15.10.2013)
Published in Human molecular genetics (15.10.2013)
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Journal Article
VBP15, a novel anti‐inflammatory and membrane‐stabilizer, improves muscular dystrophy without side effects
Heier, Christopher R., Damsker, Jesse M., Yu, Qing, Dillingham, Blythe C., Huynh, Tony, Van der Meulen, Jack H., Sali, Arpana, Miller, Brittany K., Phadke, Aditi, Scheffer, Luana, Quinn, James, Tatem, Kathleen, Jordan, Sarah, Dadgar, Sherry, Rodriguez, Olga C., Albanese, Chris, Calhoun, Michael, Gordish‐Dressman, Heather, Jaiswal, Jyoti K., Connor, Edward M., McCall, John M., Hoffman, Eric P., Reeves, Erica K. M., Nagaraju, Kanneboyina
Published in EMBO molecular medicine (01.10.2013)
Published in EMBO molecular medicine (01.10.2013)
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Journal Article
The X‐linked Becker muscular dystrophy (bmx) mouse models Becker muscular dystrophy via deletion of murine dystrophin exons 45–47
Heier, Christopher R., McCormack, Nikki M., Tully, Christopher B., Novak, James S., Newell‐Stamper, Breanne L., Russell, Alan J., Fiorillo, Alyson A.
Published in Journal of cachexia, sarcopenia and muscle (01.04.2023)
Published in Journal of cachexia, sarcopenia and muscle (01.04.2023)
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Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children
Hathout, Yetrib, Conklin, Laurie S., Seol, Haeri, Gordish-Dressman, Heather, Brown, Kristy J., Morgenroth, Lauren P., Nagaraju, Kanneboyina, Heier, Christopher R., Damsker, Jesse M., van den Anker, John N., Henricson, Erik, Clemens, Paula R., Mah, Jean K., McDonald, Craig, Hoffman, Eric P.
Published in Scientific reports (17.08.2016)
Published in Scientific reports (17.08.2016)
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Journal Article
Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits
Heier, Christopher R, Guerron, Alfredo D, Korotcov, Alexandru, Lin, Stephen, Gordish-Dressman, Heather, Fricke, Stanley, Sze, Raymond W, Hoffman, Eric P, Wang, Paul, Nagaraju, Kanneboyina
Published in PloS one (12.11.2014)
Published in PloS one (12.11.2014)
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Journal Article
VBP15, a Novel Anti-Inflammatory, is Effective at Reducing the Severity of Murine Experimental Autoimmune Encephalomyelitis
Dillingham, Blythe C., Knoblach, Susan M., Many, Gina M., Harmon, Brennan T., Mullen, Amanda M., Heier, Christopher R., Bello, Luca, McCall, John M., Hoffman, Eric P., Connor, Edward M., Nagaraju, Kanneboyina, Reeves, Erica K. M., Damsker, Jesse M.
Published in Cellular and molecular neurobiology (01.04.2015)
Published in Cellular and molecular neurobiology (01.04.2015)
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Journal Article
Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice
Heier, Christopher R., Satta, Rosalba, Lutz, Cathleen, DiDonato, Christine J.
Published in Human molecular genetics (15.10.2010)
Published in Human molecular genetics (15.10.2010)
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Journal Article
Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction
Gogliotti, Rocky G, Quinlan, Katharina A, Barlow, Courtenay B, Heier, Christopher R, Heckman, C J, Didonato, Christine J
Published in The Journal of neuroscience (14.03.2012)
Published in The Journal of neuroscience (14.03.2012)
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Journal Article
Serum miRNAs Are Pharmacodynamic Biomarkers Associated With Therapeutic Response in Pediatric Inflammatory Bowel Disease
Batra, Suruchi K, Heier, Christopher R, Diaz-Calderon, Lina, Tully, Christopher B, Fiorillo, Alyson A, van den Anker, John, Conklin, Laurie S
Published in Inflammatory bowel diseases (01.10.2020)
Published in Inflammatory bowel diseases (01.10.2020)
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Journal Article
Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping
McCormack, Nikki M., Calabrese, Kelsey A., Sun, Christina M., Tully, Christopher B., Heier, Christopher R., Fiorillo, Alyson A.
Published in Molecular therapy. Nucleic acids (10.09.2024)
Published in Molecular therapy. Nucleic acids (10.09.2024)
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Journal Article
Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone
Fiorillo, Alyson A, Tully, Christopher B, Damsker, Jesse M, Nagaraju, Kanneboyina, Hoffman, Eric P, Heier, Christopher R
Published in Physiological genomics (01.09.2018)
Published in Physiological genomics (01.09.2018)
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Journal Article
Identification of Pathway-Specific Serum Biomarkers of Response to Glucocorticoid and Infliximab Treatment in Children with Inflammatory Bowel Disease
Heier, Christopher R, Fiorillo, Alyson A, Chaisson, Ellen, Gordish-Dressman, Heather, Hathout, Yetrib, Damsker, Jesse M, Hoffman, Eric P, Conklin, Laurie S
Published in Clinical and translational gastroenterology (01.09.2016)
Published in Clinical and translational gastroenterology (01.09.2016)
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Journal Article
Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy
Heier, Christopher R, Yu, Qing, Fiorillo, Alyson A, Tully, Christopher B, Tucker, Asya, Mazala, Davi A, Uaesoontrachoon, Kitipong, Srinivassane, Sadish, Damsker, Jesse M, Hoffman, Eric P, Nagaraju, Kanneboyina, Spurney, Christopher F
Published in Life science alliance (01.02.2019)
Published in Life science alliance (01.02.2019)
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