GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme
Sherpa, Dawafuti, Chrustowicz, Jakub, Qiao, Shuai, Langlois, Christine R., Hehl, Laura A., Gottemukkala, Karthik Varma, Hansen, Fynn M., Karayel, Ozge, von Gronau, Susanne, Prabu, J. Rajan, Mann, Matthias, Alpi, Arno F., Schulman, Brenda A.
Published in Molecular cell (03.06.2021)
Published in Molecular cell (03.06.2021)
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Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5
Hehl, Laura A., Horn-Ghetko, Daniel, Prabu, J. Rajan, Vollrath, Ronnald, Vu, D. Tung, Pérez Berrocal, David A., Mulder, Monique P. C., van der Heden van Noort, Gerbrand J., Schulman, Brenda A.
Published in Nature chemical biology (01.02.2024)
Published in Nature chemical biology (01.02.2024)
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Journal Article
Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies
Chrustowicz, Jakub, Sherpa, Dawafuti, Li, Jerry, Langlois, Christine R., Papadopoulou, Eleftheria C., Vu, D. Tung, Hehl, Laura A., Karayel, Özge, Beier, Viola, von Gronau, Susanne, Müller, Judith, Prabu, J. Rajan, Mann, Matthias, Kleiger, Gary, Alpi, Arno F., Schulman, Brenda A.
Published in Molecular cell (18.01.2024)
Published in Molecular cell (18.01.2024)
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A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity
Pérez Berrocal, David A., Vishwanatha, Thimmalapura M., Horn‐Ghetko, Daniel, Botsch, J. Josephine, Hehl, Laura A., Kostrhon, Sebastian, Misra, Mohit, Ðikić, Ivan, Geurink, Paul P., Dam, Hans, Schulman, Brenda A., Mulder, Monique P. C.
Published in Angewandte Chemie International Edition (07.08.2023)
Published in Angewandte Chemie International Edition (07.08.2023)
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Journal Article
A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity
Pérez Berrocal, David A., Vishwanatha, Thimmalapura M., Horn‐Ghetko, Daniel, Botsch, J. Josephine, Hehl, Laura A., Kostrhon, Sebastian, Misra, Mohit, Ðikić, Ivan, Geurink, Paul P., Dam, Hans, Schulman, Brenda A., Mulder, Monique P. C.
Published in Angewandte Chemie (07.08.2023)
Published in Angewandte Chemie (07.08.2023)
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Journal Article
miR-92b-3p modulates apoptosis in vascular smooth muscle cells by regulating BCL2L11, suggesting innovative therapeutic approaches for atherosclerosis
Kalies, Katrin, Köster, Jan Michael, Hehl, Laura, Daniel, Fiene, Boettcher, Solveig, Sedding, Daniel
Published in Atherosclerosis (01.08.2024)
Published in Atherosclerosis (01.08.2024)
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Journal Article
miR-127-3p modulates inflammation in injury-driven vascular remodeling and cellular senescence in vascular smooth muscle cells
Daniel, Fiene, Kalies, Katrin, Hehl, Laura, Gürlach, Simon, Köster, Jan Michael, Dutzmann, Jochen, Sedding, Daniel
Published in Atherosclerosis (01.08.2024)
Published in Atherosclerosis (01.08.2024)
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Journal Article
miR-148a-3p: A novel therapeutic candidate modulating angiogenesis and senescence for enhanced myocardial infarction recovery – experimental insights and targets explored
Hehl, Laura, Kalies, Katrin, Daniel, Fiene, Köster, Jan Michael, Gürlach, Simon, Knöpp, Kai, Dutzmann, Jochen, Hinkel, Rabea, Sedding, Daniel
Published in Atherosclerosis (01.08.2024)
Published in Atherosclerosis (01.08.2024)
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Journal Article
Abstract P3043: Mir92b-3p: A Key Regulator In Vascular Homeostasis And Remodelling
Köster, Jan Michael, Kalies, Katrin, Boettcher, Solveig, Daniel, Fiene, Hehl, Laura, Guerlach, Simon, Knoepp, Kai, Dutzmann, Jochen, SEDDING, Daniel
Published in Circulation research (04.08.2023)
Published in Circulation research (04.08.2023)
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Abstract P3046: The Effect Of MicroRNA-367-3p And MicroRNA-148a-3p On Vascular Endothelial Cells In Context Of Senescence And Infarct Healing
Hehl, Laura, Kalies, Katrin, Daniel, Fiene, Knoepp, Kai, Dutzmann, Jochen, SEDDING, Daniel, Köster, Jan Michael, Guerlach, Simon, Boettcher, Solveig
Published in Circulation research (04.08.2023)
Published in Circulation research (04.08.2023)
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Journal Article
Abstract P3044: MicroRNA-127-3p Regulates Inflammatory Response In Injury-induced Vascular Remodeling And Cellular Senescence In Vascular Smooth Muscle Cells
Daniel, Fiene, Kalies, Katrin, Hehl, Laura, Guerlach, Simon, Köster, Jan Michael, Boettcher, Solveig, Knoepp, Kai, Dutzmann, Jochen, SEDDING, Daniel
Published in Circulation research (04.08.2023)
Published in Circulation research (04.08.2023)
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Abstract P3045: MicroRNA-31-5p Is Upregulated During Neointima Formation And Promotes Smooth Muscle Cell Proliferation And Migration By Regulating Krüppel-like Factor 4 (KLF4)
Gürlach, Simon, Kalies, Katrin, Daniel, Fiene, Köster, Jan Michael, Boettcher, Solveig, Hehl, Laura, Knoepp, Kai, Dutzmann, Jochen, Daniel, Jan-Marcus, Sedding, Daniel
Published in Circulation research (04.08.2023)
Published in Circulation research (04.08.2023)
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