Interaction with the 5D3 Monoclonal Antibody Is Regulated by Intramolecular Rearrangements but Not by Covalent Dimer Formation of the Human ABCG2 Multidrug Transporter
Özvegy-Laczka, Csilla, Laczkó, Rozália, Hegedűs, Csilla, Litman, Thomas, Várady, György, Goda, Katalin, Hegedűs, Tamás, Dokholyan, Nikolay V., Sorrentino, Brian P., Váradi, András, Sarkadi, Balázs
Published in The Journal of biological chemistry (19.09.2008)
Published in The Journal of biological chemistry (19.09.2008)
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Journal Article
Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites
Telbisz, Ágnes, Hegedüs, Csilla, Váradi, András, Sarkadi, Balázs, Özvegy-Laczka, Csilla
Published in Drug metabolism and disposition (01.04.2014)
Published in Drug metabolism and disposition (01.04.2014)
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Journal Article
Lipid Regulation of the ABCB1 and ABCG2 Multidrug Transporters
Hegedüs, Csilla, Telbisz, Ágnes, Hegedűs, Tamás, Sarkadi, Balázs, Özvegy-Laczka, Csilla
Published in ABC Transporters and Cancer (2015)
Published in ABC Transporters and Cancer (2015)
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Book Chapter
Journal Article
A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial
Petak, Istvan, Kamal, Maud, Dirner, Anna, Bieche, Ivan, Doczi, Robert, Mariani, Odette, Filotas, Peter, Salomon, Anne, Vodicska, Barbara, Servois, Vincent, Varkondi, Edit, Gentien, David, Tihanyi, Dora, Tresca, Patricia, Lakatos, Dora, Servant, Nicolas, Deri, Julia, du Rusquec, Pauline, Hegedus, Csilla, Bello Roufai, Diana, Schwab, Richard, Dupain, Celia, Valyi-Nagy, Istvan T., Le Tourneau, Christophe
Published in NPJ precision oncology (23.06.2021)
Published in NPJ precision oncology (23.06.2021)
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Journal Article
Major Clinical Response to Afatinib Monotherapy in Lung Adenocarcinoma Harboring EGFR Exon 20 Insertion Mutation
Urbán, László, Dóczi, Róbert, Vodicska, Barbara, Tihanyi, Dóra, Horváth, Magdolna, Kormos, Dóra, Takács, István, Pápai-Székely, Zsolt, Póka-Farkas, Zsuzsanna, Várkondi, Edit, Schwáb, Richárd, Hegedüs, Csilla, Vályi-Nagy, István, Peták, István
Published in Clinical lung cancer (01.01.2021)
Published in Clinical lung cancer (01.01.2021)
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Journal Article
Application of fluorescent dye substrates for functional characterization of ABC multidrug transporters at a single cell level
Nerada, Zsuzsanna, Hegyi, Zoltán, Szepesi, Áron, Tóth, Szilárd, Hegedüs, Csilla, Várady, György, Matula, Zsolt, Homolya, László, Sarkadi, Balázs, Telbisz, Ágnes
Published in Cytometry. Part A (01.09.2016)
Published in Cytometry. Part A (01.09.2016)
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Journal Article
Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?
Brózik, Anna, Hegedüs, Csilla, Erdei, Zsuzsa, Hegedus, Tamás, Özvegy-Laczka, Csilla, Szakács, Gergely, Sarkadi, Balázs
Published in Expert opinion on drug metabolism & toxicology (01.05.2011)
Published in Expert opinion on drug metabolism & toxicology (01.05.2011)
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Journal Article
Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter
Telbisz, Ágnes, Hegedüs, Csilla, Özvegy-Laczka, Csilla, Goda, Katalin, Várady, György, Takáts, Zoltán, Szabó, Eszter, Sorrentino, Brian P., Váradi, András, Sarkadi, Balázs
Published in European journal of pharmaceutical sciences (23.01.2012)
Published in European journal of pharmaceutical sciences (23.01.2012)
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Journal Article
Evaluation of a computational decision support system for molecularly targeted treatment planning by the clinical outcome data of the randomized trial SHIVA01
Dirner, Anna, Doczi, Robert, Filotas, Peter, Vodicska, Barbara, Varkondi, Edit, Tihanyi, Dora, Dupain, Célia, Servant, Nicolas, Kamal, Maud, Hegedűs, Csilla, Schwab, Richárd, Le Tourneau, Christophe, Valyi-Nagy, Istvan T., Peták, István
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Driver-target-drug algorithm in the interpretation of molecular cancer profiles
Petak, Istvan, Schwab, Richard, Binder, Zsofia, Kocsis, Eva, Hegedűs, Csilla, Magyari, Zselyke, Kohanka, Andrea, Keri, Gyorgy
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
Global collaborative software solution to match patients to trials and real-time sharing of clinical experience
Rolfo, Christian Diego, Lengyel, Csongor, Hegedus, Csilla, Binder, Zsofia, Peeters, Marc, Petak, Istvan
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Pharmacological and therapeutic relevance of BRCA1 and BRCA2 variants in solid tumors
Petak, Istvan, Deri, Julia, Kanta, Eszter, Maczak-Gyongy, Agnes, Hegedus, Csilla, Varkondi, Edit, Mathiasz, Dora, Schwab, Richard, Valyi-Nagy, Istvan T.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter
Gál, Zita, Hegedüs, Csilla, Szakács, Gergely, Váradi, András, Sarkadi, Balázs, Özvegy-Laczka, Csilla
Published in Biochimica et biophysica acta (01.02.2015)
Published in Biochimica et biophysica acta (01.02.2015)
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Journal Article
Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: Implications for the emergence and reversal of cancer drug resistance
Hegedüs, Csilla, Truta-Feles, Krisztina, Antalffy, Géza, Várady, György, Német, Katalin, Özvegy-Laczka, Csilla, Kéri, György, Őrfi, László, Szakács, Gergely, Settleman, Jeffrey, Váradi, András, Sarkadi, Balázs
Published in Biochemical pharmacology (01.08.2012)
Published in Biochemical pharmacology (01.08.2012)
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Journal Article
PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter
Hegedüs, Csilla, Truta-Feles, Krisztina, Antalffy, Géza, Brózik, Anna, Kasza, Ildikó, Német, Katalin, Orbán, Tamás I., Özvegy-Laczka, Csilla, Váradi, András, Sarkadi, Balázs
Published in Biochemical and biophysical research communications (20.04.2012)
Published in Biochemical and biophysical research communications (20.04.2012)
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Journal Article
Ins and outs of the ABCG2 multidrug transporter : An update on in vitro functional assays: The Role of Human ABC Transporter ABCG2 (BCRP) in Pharmacotherapy
HEGEDÜS, Csilla, SZAKACS, Gergely, HOMOLYA, Laszlo, ORBAN, Tamas I, TELBISZ, Agnes, JANI, Marton, SARKADI, Balazs
Published in Advanced drug delivery reviews (2009)
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Published in Advanced drug delivery reviews (2009)
Journal Article
AI oncology algorithm and dynamic real-world learning health care system for precision oncology
Petak, Istvan, Hegedus, Csilla, Tihanyi, Dora, Doczi, Robert, Filotas, Peter, Mate, Attila, Bacskai, Miklos, Schwab, Richard, Valyi-Nagy, Istvan T.
Published in Journal of global oncology (07.10.2019)
Published in Journal of global oncology (07.10.2019)
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Journal Article
Major Clinical Response to Afatinib Monotherapy in Lung Adenocarcinoma Harboring EGFR Exon 20 Insertion Mutation
Urbán, László, Dóczi, Róbert, Vodicska, Barbara, Tihanyi, Dóra, Horváth, Magdolna, Kormos, Dóra, Takács, István, Pápai-Székely, Zsolt, Póka-Farkas, Zsuzsanna, Várkondi, Edit, Schwáb, Richárd, Hegedüs, Csilla, Vályi-Nagy, István, Peták, István
Published in Clinical lung cancer (01.01.2021)
Published in Clinical lung cancer (01.01.2021)
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