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Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives
Cao, Xuefei, Coyle, Jayme P., Xiong, Rui, Wang, Yiying, Heflich, Robert H., Ren, Baiping, Gwinn, William M., Hayden, Patrick, Rojanasakul, Liying
Published in In vitro cellular & developmental biology. Animal (01.02.2021)
Published in In vitro cellular & developmental biology. Animal (01.02.2021)
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Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing
Marchetti, Francesco, Cardoso, Renato, Chen, Connie L., Douglas, George R., Elloway, Joanne, Escobar, Patricia A., Harper Jr, Tod, Heflich, Robert H., Kidd, Darren, Lynch, Anthony M., Myers, Meagan B., Parsons, Barbara L., Salk, Jesse J., Settivari, Raja S., Smith-Roe, Stephanie L., Witt, Kristine L., Yauk, Carole, Young, Robert R., Zhang, Shaofei, Minocherhomji, Sheroy
Published in Nature reviews. Drug discovery (01.03.2023)
Published in Nature reviews. Drug discovery (01.03.2023)
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Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7th International Workshop on Genotoxicity Testing (IWGT)
Pfuhler, Stefan, van Benthem, Jan, Curren, Rodger, Doak, Shareen H., Dusinska, Maria, Hayashi, Makoto, Heflich, Robert H., Kidd, Darren, Kirkland, David, Luan, Yang, Ouedraogo, Gladys, Reisinger, Kerstin, Sofuni, Toshio, van Acker, Frédérique, Yang, Ying, Corvi, Raffaella
Published in Mutation Research/Genetic Toxicology and Environmental Mutagenesis (01.02.2020)
Published in Mutation Research/Genetic Toxicology and Environmental Mutagenesis (01.02.2020)
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The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup
Gollapudi, B. Bhaskar, Lynch, Anthony M., Heflich, Robert H., Dertinger, Stephen D., Dobrovolsky, Vasily N., Froetschl, Roland, Horibata, Katsuyoshi, Kenyon, Michelle O., Kimoto, Takafumi, Lovell, David P., Stankowski, Leon F., White, Paul A., Witt, Kristine L., Tanir, Jennifer Y.
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.05.2015)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.05.2015)
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Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing ( IWGT )
Dertinger, Stephen D., Li, Dingzhou, Beevers, Carol, Douglas, George R., Heflich, Robert H., Lovell, David P., Roberts, Daniel J., Smith, Robert, Uno, Yoshifumi, Williams, Andrew, Witt, Kristine L., Zeller, Andreas, Zhou, Changhui
Published in Environmental and molecular mutagenesis (26.05.2023)
Published in Environmental and molecular mutagenesis (26.05.2023)
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Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-related impurity
Robison, Timothy W., Heflich, Robert H., Manjanatha, Mugimane G., Elespuru, Rosalie, Atrakchi, Aisar, Mei, Nan, Ding, Wei
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.08.2021)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.08.2021)
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Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay
Li, Yan, Chen, David H., Yan, Jian, Chen, Ying, Mittelstaedt, Roberta A., Zhang, Yongbin, Biris, Alexandru S., Heflich, Robert H., Chen, Tao
Published in Mutation research (14.06.2012)
Published in Mutation research (14.06.2012)
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Pig‐a gene mutation database
Shemansky, Jennifer M., McDaniel, Lea Patrice, Klimas, Christopher, Dertinger, Stephen D., Dobrovolsky, Vasily N., Kimoto, Takafumi, Horibata, Katsuyoshi, Polli, James E., Heflich, Robert H.
Published in Environmental and molecular mutagenesis (01.10.2019)
Published in Environmental and molecular mutagenesis (01.10.2019)
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Transgenic Animal Models in Toxicology: Historical Perspectives and Future Outlook
Boverhof, Darrell R., Chamberlain, Mark P, Elcombe, Clifford R., Gonzalez, Frank J., Heflich, Robert H., Hernández, Lya G., Jacobs, Abigail C., Jacobson-Kram, David, Luijten, Mirjam, Maggi, Adriana, Manjanatha, Mugimane G., Benthem, Jan van, Gollapudi, B. Bhaskar
Published in Toxicological sciences (01.06.2011)
Published in Toxicological sciences (01.06.2011)
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The Genotoxicity of Acrylamide and Glycidamide in Big Blue Rats
Mei, Nan, McDaniel, Lea P., Dobrovolsky, Vasily N., Guo, Xiaoqing, Shaddock, Joseph G., Mittelstaedt, Roberta A., Azuma, Mizuo, Shelton, Sharon D., McGarrity, Lynda J., Doerge, Daniel R., Heflich, Robert H.
Published in Toxicological sciences (01.06.2010)
Published in Toxicological sciences (01.06.2010)
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Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes
Kimoto, Takafumi, Chikura, Satsuki, Suzuki, Kumiko, Kobayashi, Xiao mei, Itano, Yasuhiro, Horibata, Katsuyoshi, Honma, Masamitsu, Dobrovolsky, Vasily N., Heflich, Robert H., Miura, Daishiro, Kasahara, Yoshinori
Published in Environmental and molecular mutagenesis (01.12.2011)
Published in Environmental and molecular mutagenesis (01.12.2011)
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In vivo genotoxicity of furan in F344 rats at cancer bioassay doses
Ding, Wei, Petibone, Dayton M., Latendresse, John R., Pearce, Mason G., Muskhelishvili, Levan, White, Gene A., Chang, Ching-Wei, Mittelstaedt, Roberta A., Shaddock, Joseph G., McDaniel, Lea P., Doerge, Daniel R., Morris, Suzanne M., Bishop, Michelle E., Manjanatha, Mugimane G., Aidoo, Anane, Heflich, Robert H.
Published in Toxicology and applied pharmacology (01.06.2012)
Published in Toxicology and applied pharmacology (01.06.2012)
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Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines
Ali, Rahat, Mittelstaedt, Roberta A., Shaddock, Joseph G., Ding, Wei, Bhalli, Javed A., Khan, Qaiser M., Heflich, Robert H.
Published in Mutation research (14.07.2011)
Published in Mutation research (14.07.2011)
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International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories
Dertinger, Stephen D., Phonethepswath, Souk, Weller, Pamela, Nicolette, John, Murray, Joel, Sonders, Paul, Vohr, Hans-Werner, Shi, Jing, Krsmanovic, Ljubica, Gleason, Carol, Custer, Laura, Henwood, Andrew, Sweder, Kevin, Stankowski Jr, Leon F., Roberts, Daniel J., Giddings, Amanda, Kenny, Julia, Lynch, Anthony M., Defrain, Céline, Nesslany, Fabrice, van der Leede, Bas-jan M., Van Doninck, Terry, Schuermans, Ann, Tanaka, Kentaro, Hiwata, Yoshie, Tajima, Osamu, Wilde, Eleanor, Elhajouji, Azeddine, Gunther, William C., Thiffeault, Catherine J., Shutsky, Thomas J., Fiedler, Ronald D., Kimoto, Takafumi, Bhalli, Javed A., Heflich, Robert H., MacGregor, James T.
Published in Environmental and molecular mutagenesis (01.12.2011)
Published in Environmental and molecular mutagenesis (01.12.2011)
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