Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations
Neumann, Martin, Heesch, Sandra, Schlee, Cornelia, Schwartz, Stefan, Gökbuget, Nicola, Hoelzer, Dieter, Konstandin, Nikola P., Ksienzyk, Bianka, Vosberg, Sebastian, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Raff, Thorsten, Brüggemann, Monika, Hofmann, Wolf-Karsten, Hecht, Jochen, Bohlander, Stefan K., Greif, Philipp A., Baldus, Claudia D.
Published in Blood (06.06.2013)
Published in Blood (06.06.2013)
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FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors
Neumann, Martin, Coskun, Ebru, Fransecky, Lars, Mochmann, Liliana H, Bartram, Isabelle, Sartangi, Nasrin Farhadi, Heesch, Sandra, Gökbuget, Nicola, Schwartz, Stefan, Brandts, Christian, Schlee, Cornelia, Haas, Rainer, Dührsen, Ulrich, Griesshammer, Martin, Döhner, Hartmut, Ehninger, Gerhard, Burmeister, Thomas, Blau, Olga, Thiel, Eckhard, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Baldus, Claudia D
Published in PloS one (24.01.2013)
Published in PloS one (24.01.2013)
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Journal Article
High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia
Kühnl, Andrea, Gökbuget, Nicola, Stroux, Andrea, Burmeister, Thomas, Neumann, Martin, Heesch, Sandra, Haferlach, Torsten, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia D.
Published in Blood (06.05.2010)
Published in Blood (06.05.2010)
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Journal Article
Expression of IGFBP7 in acute leukemia is regulated by DNA methylation
Heesch, Sandra, Bartram, Isabelle, Neumann, Martin, Reins, Jana, Mossner, Maximilian, Schlee, Cornelia, Stroux, Andrea, Haferlach, Torsten, Goekbuget, Nicola, Hoelzer, Dieter, Hofmann, Wolf‐Karsten, Thiel, Eckhard, Baldus, Claudia D.
Published in Cancer science (01.01.2011)
Published in Cancer science (01.01.2011)
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Journal Article
Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia
HEESCH, Sandra, GOEKBUGET, Nicola, HOELZER, Dieter, THIEL, Eckhard, HOFMANN, Wolf-Karsten, BALDUS, Claudia D, STROUX, Andrea, TANCHEZ, Jutta Ortiz, SCHLEE, Cornelia, BURMEISTER, Thomas, SCHWARTZ, Stefan, BLAU, Olga, KEILHOLZ, Ulrich, BUSSE, Antonia
Published in Haematologica (Roma) (01.06.2010)
Published in Haematologica (Roma) (01.06.2010)
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Journal Article
Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization
Heesch, Sandra, Neumann, Martin, Schwartz, Stefan, Bartram, Isabelle, Schlee, Cornelia, Burmeister, Thomas, Hänel, Matthias, Ganser, Arnold, Heuser, Michael, Wendtner, Clemens-Martin, Berdel, Wolfgang E., Gökbuget, Nicola, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia D.
Published in Annals of hematology (01.06.2013)
Published in Annals of hematology (01.06.2013)
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Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
Kranz, Lena M., Diken, Mustafa, Haas, Heinrich, Kreiter, Sebastian, Loquai, Carmen, Reuter, Kerstin C., Meng, Martin, Fritz, Daniel, Vascotto, Fulvia, Hefesha, Hossam, Grunwitz, Christian, Vormehr, Mathias, Hüsemann, Yves, Selmi, Abderraouf, Kuhn, Andreas N., Buck, Janina, Derhovanessian, Evelyna, Rae, Richard, Attig, Sebastian, Diekmann, Jan, Jabulowsky, Robert A., Heesch, Sandra, Hassel, Jessica, Langguth, Peter, Grabbe, Stephan, Huber, Christoph, Türeci, Özlem, Sahin, Ugur
Published in Nature (London) (16.06.2016)
Published in Nature (London) (16.06.2016)
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Journal Article
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
Sahin, Ugur, Derhovanessian, Evelyna, Miller, Matthias, Kloke, Björn-Philipp, Simon, Petra, Löwer, Martin, Bukur, Valesca, Tadmor, Arbel D., Luxemburger, Ulrich, Schrörs, Barbara, Omokoko, Tana, Vormehr, Mathias, Albrecht, Christian, Paruzynski, Anna, Kuhn, Andreas N., Buck, Janina, Heesch, Sandra, Schreeb, Katharina H., Müller, Felicitas, Ortseifer, Inga, Vogler, Isabel, Godehardt, Eva, Attig, Sebastian, Rae, Richard, Breitkreuz, Andrea, Tolliver, Claudia, Suchan, Martin, Martic, Goran, Hohberger, Alexander, Sorn, Patrick, Diekmann, Jan, Ciesla, Janko, Waksmann, Olga, Brück, Alexandra-Kemmer, Witt, Meike, Zillgen, Martina, Rothermel, Andree, Kasemann, Barbara, Langer, David, Bolte, Stefanie, Diken, Mustafa, Kreiter, Sebastian, Nemecek, Romina, Gebhardt, Christoffer, Grabbe, Stephan, Höller, Christoph, Utikal, Jochen, Huber, Christoph, Loquai, Carmen, Türeci, Özlem
Published in Nature (London) (13.07.2017)
Published in Nature (London) (13.07.2017)
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Journal Article
Mutational spectrum of adult T-ALL
Neumann, Martin, Vosberg, Sebastian, Schlee, Cornelia, Heesch, Sandra, Schwartz, Stefan, Gökbuget, Nicola, Hoelzer, Dieter, Graf, Alexander, Krebs, Stefan, Bartram, Isabelle, Blum, Helmut, Brüggemann, Monika, Hecht, Jochen, Bohlander, Stefan K, Greif, Philipp A, Baldus, Claudia D
Published in Oncotarget (20.02.2015)
Published in Oncotarget (20.02.2015)
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Journal Article
Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL
Bartram, Isabelle, Erben, Ulrike, Ortiz-Tanchez, Jutta, Blunert, Katja, Schlee, Cornelia, Neumann, Martin, Heesch, Sandra, Baldus, Claudia D
Published in BMC cancer (08.10.2015)
Published in BMC cancer (08.10.2015)
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Journal Article
MicroRNA profiling reveals aberrant microRNA expression in adult ETP-ALL and functional studies implicate a role for miR-222 in acute leukemia
Coskun, Ebru, Neumann, Martin, Schlee, Cornelia, Liebertz, Frauke, Heesch, Sandra, Goekbuget, Nicola, Hoelzer, Dieter, Baldus, Claudia D
Published in Leukemia research (01.06.2013)
Published in Leukemia research (01.06.2013)
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Journal Article
Acute leukemias of ambiguous lineage in adults: molecular and clinical characterization
Heesch, Sandra, Neumann, Martin, Schwartz, Stefan, Bartram, Isabelle, Schlee, Cornelia, Burmeister, Thomas, Hänel, Matthias, Ganser, Arnold, Heuser, Michael, Wendtner, Clemens-Martin, Berdel, Wolfgang E., Gökbuget, Nicola, Hoelzer, Dieter, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia D.
Published in Annals of hematology (01.06.2013)
Published in Annals of hematology (01.06.2013)
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Journal Article
Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma
Hilf, Norbert, Kuttruff-Coqui, Sabrina, Frenzel, Katrin, Bukur, Valesca, Stevanović, Stefan, Gouttefangeas, Cecile, Platten, Michael, Tabatabai, Ghazaleh, Dutoit, Valerie, van der Burg, Sjoerd H., Straten, Per thor, Martinez-Ricarte, Francisco, Ponsati, Berta, Okada, Hideho, Lassen, Ulrik, Admon, Arie, Ottensmeier, Christian H., Ulges, Alexander, Kreiter, Sebastian, von Deimling, Andreas, Skardelly, Marco, Migliorini, Denis, Kroep, Judith R., Idorn, Manja, Rodon, Jordi, Piro, Jordi, Poulsen, Hans S., Shraibman, Bracha, McCann, Katy, Mendrzyk, Regina, Lower, Martin, Stieglbauer, Monika, Britten, Cedrik M., Capper, David, Welters, Marij J. P., Sahuquillo, Juan, Kiesel, Katharina, Derhovanessian, Evelyna, Rusch, Elisa, Bunse, Lukas, Song, Colette, Heesch, Sandra, Wagner, Claudia, Kemmer-Bruck, Alexandra, Ludwig, Jorg, Castle, John C., Schoor, Oliver, Tadmor, Arbel D., Green, Edward, Fritsche, Jens, Meyer, Miriam, Pawlowski, Nina, Dorner, Sonja, Hoffgaard, Franziska, Rossler, Bernhard, Maurer, Dominik, Weinschenk, Toni, Reinhardt, Carsten, Huber, Christoph, Rammensee, Hans-Georg, Singh-Jasuja, Harpreet, Sahin, Ugur, Dietrich, Pierre-Yves, Wick, Wolfgang
Published in Nature (London) (01.02.2019)
Published in Nature (London) (01.02.2019)
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Journal Article
Low Expression Of BCL11B Predicts Poor Overall Survival In Adult Standard Risk T-ALL
Bartram, Isabelle, Gökbuget, Nicola, Schlee, Cornelia, Heesch, Sandra, Fransecky, Lars, Schwartz, Stefan, Hoelzer, Dieter, Neumann, Martin, Baldus, Claudia D.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia
Kühnl, Andrea, Kaiser, Martin, Neumann, Martin, Fransecky, Lars, Heesch, Sandra, Radmacher, Michael, Marcucci, Guido, Bloomfield, Clara D, Hofmann, Wolf-Karsten, Thiel, Eckhard, Baldus, Claudia D
Published in Leukemia research (01.12.2011)
Published in Leukemia research (01.12.2011)
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Journal Article
Abstract CT020: MERIT: introducing individualized cancer vaccines for the treatment of TNBC - a phase I trial
Heesch, Sandra, Bukur, Valesca, Buck, Janina, Diekmann, Jan, Diken, Mustafa, Ewen, Kerstin, Haas, Heinrich, Kemmer-Brueck, Alexandra, Kloke, Björn-Philipp, Kreiter, Sebastian, Kuhn, Andreas N., Kuehlcke, Klaus, Loewer, Martin, Paruzynski, Anna, Schultheiß, Kathrin, Schwarck, Doreen, Schmidt, Marcus, André, Fabrice, De Greve, Jacques, Kuendig, Thomas, Lindman, Henrik, Pascolo, Steve, Sjöblom, Tobias, Thielemans, Kris, Zitvogel, Laurence, Türeci, Özlem, Sahin, Ugur
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract CT022: IVAC® MUTANOME - A first-in-human phase I clinical trial targeting individual mutant neoantigens for the treatment of melanoma
Miller, Matthias, Loquai, Carmen, Kloke, Björn-Philipp, Attig, Sebastian, Bidmon, Nicole, Bolte, Stefanie, Bukur, Valesca, Derhovanessian, Evelyna, Diekmann, Jan, Filbry, Angela, Heesch, Sandra, Hoeller, Christoph, Kuehlcke, Klaus, Langer, David, Loewer, Martin, Mueller, Felicitas, Ortseifer, Inga, Otte, Burkhard, Paruzynski, Anna, Rae, Richard, Schroers, Barbara, Seck, Christine, Spiess, Kristina, Tadmor, Arbel D., Vogler, Isabel, Vormehr, Mathias, Kemmer-Brueck, Alexandra, Kuhn, Andreas N., Luxemburger, Ulrich, Kreiter, Sebastian, Utikal, Jochen, Grabbe, Stephan, Tuereci, Oezlem, Sahin, Ugur
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients
Bartram, Isabelle, Gökbuget, Nicola, Schlee, Cornelia, Heesch, Sandra, Fransecky, Lars, Schwartz, Stefan, Stuhlmann, Reingard, Schäfer-Eckhart, Kerstin, Starck, Michael, Reichle, Albrecht, Hoelzer, Dieter, Baldus, Claudia D, Neumann, Martin
Published in Journal of hematology and oncology (15.07.2014)
Published in Journal of hematology and oncology (15.07.2014)
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Journal Article
Abstract CT201: The Mutanome Engineered RNA Immuno-Therapy (MERIT) project
Heesch, Sandra, Britten, Cedrik M., Bukur, Valesca, Buck, Janina, Castle, John, Diekmann, Jan, Diken, Mustafa, Frenzel, Katrin, Kreiter, Sebastian, Kuhn, Andreas N., Kuehlcke, Klaus, Loewer, Martin, Haas, Heinrich, Kemmer-Brueck, Alexandra, Kloke, Bjoern-Philipp, Otte, Burkhard, Paruzynski, Anna, Petri, Sebastian, Schwarck-Kokarakis, Doreen, Schmidt, Marcus, André, Fabrice, De Greve, Jacques, Kuendig, Thomas, Lindman, Henrik, Pascolo, Steve, Sjöblom, Tobias, Thielemans, Kris, Zitvogel, Laurence, Tuereci, Oezlem, Sahin, Ugur
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract CT202: IVAC MUTANOME: Individualized vaccines for the treatment of cancer
Kloke, Bjoern-Philipp, Britten, Cedrik M., Loquai, Carmen, Löwer, Martin, Attig, Sebastian, Bukur, Valesca, Bidmon, Nicole, Derhovanessian, Evelyna, Diekmann, Jan, Diken, Mustafa, Filbry, Angela, Grabbe, Stephan, Heesch, Sandra, Hoeller, Christoph, Langer, David, Luxemburger, Uli, Miller, Matthias, Mueller, Felicitas, Mueller-Brenne, Tina, Ortseifer, Inga, Otte, Burkhard, Paruzynski, Anna, Petri, Sebastian, Rae, Richard, Seck, Christine, Spieß, Kristina, Tadmor, Arbel D., Utikal, Jochen, Kuehlke, Klaus, Castle, John, Kemmer-Brueck, Alexandra, Vogler, Isabel, Kuhn, Andreas N., Kreiter, Sebastian, Tuereci, Oezlem, Sahin, Ugur
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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